TITLE

Eicosanoid mediator expression in mononuclear and polymorphonuclear cells in normal subjects and patients with atopic asthma and cystic fibrosis

AUTHOR(S)
Kuitert, L. M.; Newton, R.; Barnes, N. C.; Adcock, I. M.; Barnes, P. J.
PUB. DATE
December 1996
SOURCE
Thorax;Dec1996, Vol. 51 Issue 12, p1223
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
66084909

 

Related Articles

  • Production of TNF-α by Peripheral Blood Mononuclear Cells through Activation of Nuclear Factor κΒ by Specific Allergen Stimulation in Patients with Atopic Asthma. Mitsuta, Kazuko; Matsuse, Hiroto; Fukushima, Chizu; Kawano, Tetsuya; Tomari, Shinya; Obase, Yasushi; Goto, Shinji; Urata, Yoshishige; Shimoda, Terufumi; Kondo, Takahito; Kohno, Shigeru // Allergy & Asthma Proceedings;Jan/Feb2003, Vol. 24 Issue 1, p19 

    Stimulation by specific allergens induces inflammatory cytokine production, from peripheral blood mononuclear cells (PBMCs) in patients with atopic asthma, but the mechanism remains unknown. PBMCs were collected from six patients with atopic asthma with an immunoglobulin E-radioallergosorbent...

  • Association of Cystic Fibrosis with Abnormalities in Fatty Acid Metabolism. Freedman, Steven D.; Blanco, Paola G.; Zaman, Munir M.; Shea, Julie C.; Ollero, Mario; Hopper, Isabel K.; Weed, Deborah A.; Gelrud, Andres; Regan, Meredith M.; Laposata, Michael; Alvarez, Juan G.; O'Sullivan, Brian P. // New England Journal of Medicine;2/5/2004, Vol. 350 Issue 6, p560 

    Background: Patients with cystic fibrosis have altered levels of plasma fatty acids. We previously demonstrated that arachidonic acid levels are increased and docosahexaenoic acid levels are decreased in affected tissues from cystic fibrosis–knockout mice. In this study we determined...

  • RANTES Gene Promoter Polymorphisms Are Associated with Bronchial Hyperresponsiveness in Korean Children with Asthma. Myung Hyun Sohn; Seung-Hyun Kim; Kyung-Won Kim; Hye Mi Jee; Hae-Sim Park; Kyu-Earn Kim // Lung;Jan/Feb2008, Vol. 186 Issue 1, p37 

    Regulated upon activation in normal T cells, expressed, and secreted (RANTES) protein is abundantly expressed during atopic asthma, suggesting that it is an important mediator of this disease. The aim of this study was to evaluate the possible role of RANTES promoter polymorphisms in children...

  • Mucin Gene Expression (MUC1, MUC2, and MUC5/5AC) in Nasal Epithelial Cells of Cystic Fibrosis... Voynow, J.A.; Selby, D.M.; Rose, M.C. // Lung;1998, Vol. 176 Issue 5, p345 

    Studies mucin gene expression in nasal epithelial cells of cystic fibrosis, allergic rhinitis and normal individuals. Morbidity and mortality in cystic fibrosis; Mucin transcript levels in nasal epithelium.

  • Significant Changes of 5-Hydroxytriptamine 3A Receptor Gene Expression in Peripheral Blood Mononuclear Cells of Allergic Asthmatic Patients. Amirabad, Leila Mohammadi; Ahangari, Ghasem; Deilami, Gholamreza Derakhshan // Iranian Journal of Allergy, Asthma & Immunology;Feb2014, Vol. 13 Issue 1, p33 

    Asthma is a chronic inflammatory disorder of the airways. The stress is a factor for asthma which indicates a disorder in the function of communicational mediators of nervous and immunological systems such as neurotransmitters. A study indicated that blood serotonin concentration increases in...

  • Local and systemic immunological parameters associated with remission of asthma symptoms in children. Waserman, Susan; Nair, Parameswaran; Snider, Denis; Conway, Mary; Jayaram, Lata; McCleary, Lynn M.; Dolovich, Jerry; Hargreave, Frederick E.; Marshall, Jean S. // Allergy, Asthma & Clinical Immunology;2012, Vol. 8 Issue 1, p1 

    The immunological and clinical parameters that are associated with asthma remission are poorly understood. The cytokine and local mediator changes associated with the resolution of asthma symptoms were examined in three groups of subjects 12-18 years of age (n = 15 in each group): (a) continuing...

  • A defective type 1 response to rhinovirus in atopic asthma. Papadopoulos, N. G.; Stanciu, L. A.; Papi, A.; Holgate, S. T.; Johnston, S. L. // Thorax;Apr2002, Vol. 57 Issue 4, p328 

    Background: Rhinoviruses (RVs) ore the most frequent precipitants of the common cold and asthma exacerbations, but little is known about the immune response to these viruses and its potential implications in the pathogenesis of asthma. Methods: Peripheral blood mononuclear cells (PBMC) from...

  • A Lipid Mediator Hepoxilin A3 Is a Natural Inducer of Neutrophil Extracellular Traps in Human Neutrophils. Douda, David N.; Grasemann, Hartmut; Pace-Asciak, Cecil; Palaniyar, Nades // Mediators of Inflammation;2/16/2015, Vol. 2015, p1 

    Pulmonary exacerbations in cystic fibrosis airways are accompanied by inflammation, neutrophilia, and mucous thickening. Cystic fibrosis sputum contains a large amount of uncleared DNA contributed by neutrophil extracellular trap (NET) formation from neutrophils. The exact mechanisms of the...

  • Intracellular (polymorphonuclear) magnesium content in patients with bronchial asthma between attacks. Fantidis, Panayotis; Ruiz Cacho, Jesús; Marín, Mercedes; Madero Jarabo, Rosario; Solera, Jesús; Herrero, Elisa // Journal of the Royal Society of Medicine;Aug1995, Vol. 88 Issue 8, p441 

    Previous studies have demonstrated the role of polymorphonuclears in asthma, the importance of increases in intracellular concentrations of ionized calcium in the release of chemical mediators, the role of magnesium as natural calcium channel blocker, and the importance of magnesium deficiency...

  • Muscling into cystic Fibrosis airways. Sutcliffe, A. M.; Knox, A. J. // Thorax;Mar2005, Vol. 60 Issue 3, p181 

    The article focuses on cystic fibrosis that develop progressive airflow obstruction. Pathological studies of the lungs of patients obtained either at necropsy or transplantation or lobectomy showed an increase in smooth muscle area compared with healthy controls or patients with chronic...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics