Interleukin 10 (IL-10) regulation of tumour necrosis factor alpha (TNF-alpha) from human alveolar macrophages and peripheral blood monocytes

Armstrong, L.; Jordan, N.; Millar, A.
February 1996
Thorax;Feb1996, Vol. 51 Issue 2, p143
Academic Journal
No abstract available.


Related Articles

  • Increased interleukin-13 expression in patients with sarcoidosis. Hauber H-P; Gholami D; Meyer A; Pforte A // Thorax;Jun2003, Vol. 58 Issue 6, p519 

    BACKGROUND: Sarcoidosis is a systemic granulomatous disorder of unknown origin. Lymphocytic inflammation is dominated by expression of Th1 type cytokines such as tumour necrosis factor alpha (TNFalpha). Interleukin 13 (IL-13) is a Th2 cytokine which is expressed by CD4+ T cells and has been...

  • Enhanced Production of Tumor Necrosis Factor-alpha and Interleukin-6 Due to Prolonged Response to Lipopolysaccharide in Human Macrophages Infected In Vitro with Human Immunodeficiency Virus Type 1. Bergamini, Alberto; Faggioli, Emanuela; Bolacchi, Francesca; Gessani, Sandra; Cappannoli, Luisa; Uccella, Ilaria; Demin, Flavio; Capozzi, Marcella; Cicconi, Rosella; Placido, Roberto; Vendetti, Silvia; Mancino, Giorgio; Colizzi, Vittorio; Rocchi, Giovanni // Journal of Infectious Diseases;4/1/99, Vol. 179 Issue 4 

    Examines the elevation of circulating tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 in HIV type-1 infection. Contribution of the overproduction of cytokines to AIDS pathogenesis; Expression of TNF-alpha and IL-6 in human macrophages; Response of TNF-alpha and IL-6 to...

  • Cigarette smoke impairs cytokine responses and BCG containment in alveolar macrophages. van Zyl-Smit, Richard N.; Binder, Anke; Meldau, Richard; Semple, Patricia L.; Evans, Alicia; Smith, Peter; Bateman, Eric D.; Dheda, Keertan // Thorax;Apr2014, Vol. 69 Issue 4, p363 

    Background: There is a strong epidemiological link between smoking and tuberculosis (TB), but the association is confounded by socioeconomic and other factors. A direct relationship between cigarette smoke and poor treatment-related outcomes in patients with TB is therefore questionable. We...

  • Possible Impact of Microglial Cells and the Monocyte-Macrophage System on Suicidal Behavior. Steiner, Johann; Gos, Tomasz; Bogerts, Bernhard; Bielau, Hendrik; Drexhage, Hemmo A.; Bernstein, Hans-Gert // CNS & Neurological Disorders - Drug Targets;Nov2013, Vol. 12 Issue 7, p971 

    Immune dysfunction, including monocytosis, increased blood levels of interleukin-1 (IL-1), interleukin-6 (IL- 6) and tumor necrosis factor-alpha (TNF-alpha), as well as an increased microglial density in certain brain areas, have been described in schizophrenia and depression. Interestingly,...

  • Influence of Phthalates on in vitro Innate and Adaptive Immune Responses. Hansen, Juliana Frohnert; Nielsen, Claus Henrik; Brorson, Marianne Møller; Frederiksen, Hanne; Hartoft-Nielsen, Marie-Louise; Rasmussen, Åse Krogh; Bendtzen, Klaus; Feldt-Rasmussen, Ulla // PLoS ONE;Jun2015, Vol. 10 Issue 6, p1 

    Phthalates are a group of endocrine disrupting chemicals, suspected to influence the immune system. The aim of this study was to investigate the influence of phthalates on cytokine secretion from human peripheral blood mononuclear cells. Escherichia coli lipopolysaccharide and...

  • Suppressive activity of a macrolide antibiotic, roxithromycin, on pro-inflammatory cytokine production in vitro and in vivo. Suzaki, H.; Asano, K.; Ohki, S.; Kanai, K.; Mizutani, T.; Hisamitsu, T. // Mediators of Inflammation;Aug99, Vol. 8 Issue 4/5, p199 

    THIS study was designed to examine the influence of a macrolide antibiotic, roxithromycin (RXM), on the production of pro-inflammatory cytokines, interleukin (IL)-1 beta and tumor necrosis factor (TNF)-alpha. In the first experiments, we examined the effect of RXM on in vitro cytokine production...

  • Regulation of TNF-α by 1α,25-dihydroxyvitamin D[sub3] in human macrophages from CAPD patients. Cohen, Merav Lahav; Doudevani, Amos; Chaimovitz, Cidio; Shany, Shraga // Kidney International;Jan2001, Vol. 59 Issue 1, p69 

    Analyzes the regulation of tumor necrosis factor (TNF)-alpha by dihydroxyvitamin in human macrophages from patients with continuous ambulatory peritoneal dialysis. Expression of TNF in messenger RNA; Determination on the bactericidal activity of peritoneal macrophages.

  • Non-infected preterm parturition is related to increased concentrations of IL-6, IL-8 and MCP-1 in human cervix. Törnblom, Susanne Abelin; Klimaviciute, Aurelija; Byström, Birgitta; Chromek, Milan; Brauner, Annelie; Ekman-Ordeberg, Gunvor // Reproductive Biology & Endocrinology;2005, Vol. 3, p39 

    Background: Human cervical ripening is an inflammatory process. In labour at term the mRNA-levels and protein concentrations for interleukin-6 (IL-6) and IL-8 in cervix significantly increase. The aim of this study was to investigate if there are differences in the inflammatory process of...

  • Effect of homocysteine on cytokine production by human endothelial cells and monocytes. Dalal, S; Parkin, SM; Homer-Vanniasinkam, S; Nicolaou, A // Annals of Clinical Biochemistry;Sep2003, Vol. 40 Issue 5, p534 

    Background: Hyperhomocysteinaemia is an independent risk factor in the development of cardiovascular disease. Although homocysteine has been shown to affect endothelial cell function, the mechanisms by which it induces disease states are still poorly understood. Here, we report the ability of...

  • Responses of Murine and Human Macrophages to Leptospiral Infection: A Study Using Comparative Array Analysis. Xue, Feng; Zhao, Xinghui; Yang, Yingchao; Zhao, Jinping; Yang, Yutao; Cao, Yongguo; Hong, Cailing; Liu, Yuan; Sun, Lan; Huang, Minjun; Gu, Junchao // PLoS Neglected Tropical Diseases;Oct2013, Vol. 7 Issue 10, p1 

    Leptospirosis is a re-emerging tropical infectious disease caused by pathogenic Leptospira spp. The different host innate immune responses are partially related to the different severities of leptospirosis. In this study, we employed transcriptomics and cytokine arrays to comparatively calculate...


Read the Article


Sign out of this library

Other Topics