Peripheral nerve functions in chronic alcoholic patients on disulfiram: a six month follow up

Palliyath, S K; Schwartz, B D; Gant, L
March 1990
Journal of Neurology, Neurosurgery & Psychiatry;Mar1990, Vol. 53 Issue 3, p227
Academic Journal
journal article
No abstract available.


Related Articles

  • A Case of Psychosis in Disulfiram Treatment for Alcoholism. de Melo, Raquel Calvão; Lopes, Rui; Alves, José Carlos // Case Reports in Psychiatry;2014, p1 

    Background. Disulfiram, a drug used in the treatment of alcohol dependence, is an inhibitor of dopamine-β-hydroxylase causing an increase in the concentration of dopamine in the mesolimbic system. In addition to the physical symptoms associated with concomitant use of alcohol, disulfiram may...

  • Disulfiram Treatment of Alcoholism. Chick, Jonathan; Gough, Kevin; Falkowski, Wojciech; Kershaw, Peter; Hore, Brian; Mehta, Brij; Ritson, Bruce; Ropner, Richard; Torley, Denis // British Journal of Psychiatry;Jul92, Vol. 161, p84 

    To assess the efficacy of supervised disulfiram as an adjunct to out-patient treatment of alcoholics, a randomised, partially blind, six-month follow-up study was conducted in which 126 patients received 200 mg disulfiram or 100 mg vitamin C under the supervision of a nominated informant. In the...

  • Disulfiram.  // Reactions Weekly;9/1/2007, Issue 1167, p13 

    The article presents a case study of a 57-year-old man with a history of chronic alcoholism who developed hepatitis while receiving disulfiram as an adjunct for maintaining alcohol abstinence. The patient started receiving disulfiram after a relapse following 12 years of sobriety. Eight months...

  • Disulfiram Implantation Critically Evaluated. Malcolm, M. T.; Madden, J. S.; Williams, A. E. // British Journal of Psychiatry;Nov74, Vol. 125, p485 

    The article presents a study on the use of disulfiram implantation as a method of treatment for some alcoholics. The purpose of oral disulfiram therapy is to cause an unpleasant reaction to alcohol in which the patient will be forced to stop drinking. In this study, about sixty-two alcoholic...

  • A ONE-YEAR PRAGMATIC TRIAL OF NALTREXONE VS DISULFIRAM IN THE TREATMENT OF ALCOHOL DEPENDENCE. de Sousa, Alan; de Sousa, Avinash // Alcohol & Alcoholism;Nov/Dec2004, Vol. 39 Issue 6, p528 

    Aims: To compare the efficacy of naltrexone and disulfirain in preventing an alcoholic relapse in routine clinical practice in an Indian metropolis. Methods: Hundred alcohol-dependent men, for whom a family member would accompany the patient to follow-up appointments, were randomly allocated to...

  • Safety issues concerning the use of disulfiram in treating alcohol dependence. Chick, J. // Drug Safety;May1999, Vol. 20 Issue 5, p427 

    Disulfiram is known to cause hepatitis, which is sometimes fatal. The best estimate of the frequency of disulfiram-induced fatal hepatitis is 1 case in 30,000 patients treated/year. Its appears to be more common in patients given disulfiram for the treatment of nickel sensitivity. Frequent blood...

  • Mesenchymal stem cells in iatrogenic facial nerve paralysis: a possible role in the future. Caylan, Refik; Bektas, Devrim; Dikmen, Tamer; Bektas, Ozlen; Omay, Serdar; Ovali, Ercument // European Archives of Oto-Rhino-Laryngology;Oct2006, Vol. 263 Issue 10, p963 

    Iatrogenic facial nerve paralysis is one of the major and drastic complications of ear surgery. We report a case of a 20-year-old female patient with simple chronic otitis media who underwent mastoidectomy and tympanoplasty. During the mastoidectomy process the facial nerve was unintentionally...

  • Platelet Function in Alcoholics Treated with Disulfiram. Randi, Maria Luigia; Zanella, Ilia; Pujatti, Piero; Soini, Barbara; Girolami, Antonio // Clinical & Applied Thrombosis/Hemostasis;Winter1996, Vol. 2 Issue 1, p51 

    Disulfiram is usually used in alcoholics as aversion therapy. It binds to various enzymes and proteins in blood and in tissues. In particular, it inhibits the thromboxane synthetase in human platelets and, for this reason, it has been surmised that disulfiram has a possible effect on platelet...

  • Disulfiram.  // Reactions Weekly;3/3/2012, Issue 1391, p20 

    The article describes the case of a 46-year-old patient who developed optic neuropathy after receiving disulfiram for chronic alcoholism.

  • Peripheral neuropathy as initial manifestation of primary systemic vasculitides. Wolf, Joachim; Schmitt, Verena; Palm, Frederic; Grau, Armin; Bergner, Raoul // Journal of Neurology;Apr2013, Vol. 260 Issue 4, p1061 

    Peripheral neuropathies are well-known complications of primary systemic vasculitides. In rare cases, peripheral neuropathies are among the first symptoms of these diseases. In this prospective study, 89 consecutive adult patients with newly diagnosed primary systemic vasculitis were screened,...


Read the Article


Sign out of this library

Other Topics