TITLE

Lower motor neuron degeneration and familial predisposition to colonic neoplasia in two adult siblings

AUTHOR(S)
Shaw, P J; Ince, P G; Slade, J; Burn, J; Cartlidge, N E
PUB. DATE
November 1991
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Nov1991, Vol. 54 Issue 11, p993
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
No abstract available.
ACCESSION #
66023675

 

Related Articles

  • reaction of degeneration.  // Taber's Cyclopedic Medical Dictionary;2005, p1856 

    A definition of the term "reaction of degeneration" is presented. It refers to a change or process in muscle reactivity to electricity that is seen in lower motor neuron paralysis.

  • familial cancer syndrome.  // Taber's Cyclopedic Medical Dictionary;2005, p776 

    A definition of the medical term "family cancer syndrome" is presented. Family cancer syndrome refers to any genetic predisposition to cancer that is found in several generations of kindred. Some of the recognized cancer syndromes that recur in families include the multiple endocrine neoplasias,...

  • A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques. Moreno, Fermin; Rabinovici, Gil D.; Karydas, Anna; Miller, Zachary; Sandy Chan Hsu; Legati, Andrea; Jamie Fong; Schonhaut, Daniel; Esselmann, Hermann; Watson, Christa; Stephens, Melanie L.; Kramer, Joel; Wiltfang, Jens; Seeley, William W.; Miller, Bruce L.; Coppola, Giovanni; Grinberg, Lea Tenenholz // Acta Neuropathologica Communications;9/5/2015, Vol. 3 Issue 1, p1 

    Introduction: Although TDP-43 is the main constituent of the ubiquitinated cytoplasmic inclusions in the most common forms of frontotemporal lobar degeneration, TARDBP mutations are not a common cause of familial frontotemporal dementia, especially in the absence of motor neuron disease....

  • TDP-43 in differential diagnosis of motor neuron disorders. Dickson, Dennis; Josephs, Keith; Amador-Ortiz, Catalina // Acta Neuropathologica;Jul2007, Vol. 114 Issue 1, p71 

    Motor neuron disorders are clinically and pathologically heterogeneous. They can be classified into those that affect primarily upper motor neurons, lower motor neurons or both. The most common disorder to affect both upper and lower motor neurons is amyotrophic lateral sclerosis (ALS). Some...

  • ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Greenway, Matthew J.; Andersen, Peter M.; Russ, Carsten; Ennis, Sean; Cashman, Susan; Donaghy, Colette; Patterson, Victor; Swingler, Robert; Kieran, Dairin; Prehn, Jochen; Morrison, Karen E.; Green, Andrew; Acharya, K. Ravi; Brown Jr., Robert H.; Hardiman, Orla // Nature Genetics;Apr2006, Vol. 38 Issue 4, p411 

    We recently identified angiogenin (ANG) as a candidate susceptibility gene for amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder characterized by adult-onset loss of motor neurons. We now report the finding of seven missense mutations in 15 individuals, of whom four had familial...

  • Amyotrophic Lateral Sclerosis.  // Encyclopedic Reference of Molecular Pharmacology;2004, p32 

    The article presents an encyclopedia entry for amyotrophic lateral sclerosis. It is a disease of motor neurons, in which both the upper motor neurons in the cortex and the lower motor neuron in the brain stem and spinal cord degenerate progressively, leading to neurogenic atrophy of muscle...

  • Testing for Colon Neoplasia Susceptibility Variants at the Human COX2 Locus. Wiesner, Georgia L.; Platzer, Petra; Buxbaum, Sarah; Lewis, Susan; MacMillen, Mellissa; Olechnowicz, Joseph; Willis, Joseph; Chakravarti, Aravinda; Elston, Robert C.; Markowitz, Sanford D. // JNCI: Journal of the National Cancer Institute;04/18/2001, Vol. 93 Issue 8, p635 

    Examines whether the human cyclooxygenase 2 (COX2) locus may be linked to colon neoplasia in humans. Use of affected sibling-pair method to test for linkage of the human COX2 locus to colon neoplasia; Evaluation of COX2 susceptibility alleles in subpopulations of sibships with colon neoplasia.

  • Pathological involvement of the motor neuron system and hippocampal formation in motor neuron disease-inclusion dementia. Toyoshima, Yasuko; Piao, Yue-Shan; Tan, Chun-Feng; Morita, Masahiro; Tanaka, Masaharu; Oyanagi, Kiyomitsu; Okamoto, Koichi; Takahashi, Hitoshi // Acta Neuropathologica;Jul2003, Vol. 106 Issue 1, p50 

    We report two patients with motor neuron disease-inclusion dementia, with special reference to the pathology of the motor neuron system and hippocampal formation. The ages of the patients at death were 55 and 62 years, and the disease durations were 8 and 3 years, respectively. The two patients...

  • Virtual Screening for Colon Polyps. Shirley, Heather // Journal of Dental Hygiene;Winter2004, Vol. 78 Issue 1, p6 

    Focuses on the recommendation of the American Cancer Society on the screening of colorectal neoplasia for adults over the age of 50 and for young people with a family history or other risk factors. Traditional screening methods for colon polyps; Characterization of colorectal neoplasia; Number...

  • Drosophila Motor Neuron Retraction during Metamorphosis Is Mediated by Inputs from TGF-β/BMP Signaling and Orphan Nuclear Receptors. Boulanger, Ana; Farge, Morgane; Ramanoudjame, Christophe; Wharton, Kristi; Dura, Jean-Maurice // PLoS ONE;Jul2012, Vol. 7 Issue 7, p1 

    Larval motor neurons remodel during Drosophila neuro-muscular junction dismantling at metamorphosis. In this study, we describe the motor neuron retraction as opposed to degeneration based on the early disappearance of β-Spectrin and the continuing presence of Tubulin. By blocking cell...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics