TITLE

Correlation between cerebral tissue and central venous oxygen saturation during off-pump coronary bypass graft surgery

AUTHOR(S)
Harilall, Yakeen; Adam, Jamila K; Biccard, Bruce M; Reddi, Anu
PUB. DATE
March 2011
SOURCE
Perfusion;Mar2011, Vol. 26 Issue 2, p83
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We compared simultaneous regional cerebral oxygen saturation and central venous oxygen saturation at different time periods in 20 adult patients (median age, 57.9; range, 35 to 76 years) undergoing off-pump coronary artery bypass (OPCAB) graft surgery (n= 20). Mean arterial pressure (MAP), partial pressure of carbon dioxide (PcvCO2), heart rate, haematocrit (Hct), lactate and patient oxygen saturation (SpO2) were also recorded as a secondary analysis to determine independent predictors of cerebral desaturation and interactions between predictors.The cross-sectional analysis performed at each time point showed several significant moderate to strong positive correlations between central venous oxygen saturation and both right and left cerebral oxygen saturations; however, right cerebral saturations correlated better with central venous saturations than left cerebral saturation. Partial pressure of carbon dioxide (PcvCO2) was identified as a major predictor of cerebral saturation 0.59 (p < 0.001). Central venous saturation can be used as a surrogate measure of cerebral oxygen saturation during OPCAB surgery.
ACCESSION #
65974267

 

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