TITLE

Hemocompatibility of a coaxial pump catheter for less invasive heart surgery

AUTHOR(S)
Mueller, Xavier M; Augstburger, Monique; Boone, Yves; von Segesser, Ludwig K
PUB. DATE
January 2002
SOURCE
Perfusion;Jan2002, Vol. 17 Issue 1, p3
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Off-pump coronary artery bypass (OPCAB) requires heart manipulation during exposure of the lateral and posterior walls of the heart, which may cause hemodynamic instability, mainly through right ventricular dysfunction. A coaxial atrial cannula connected to a minicentrifugal pump was developed to bypass the right heart. This study was designed to test the hemocompatibility of this pump ongoing for 6 h. In five calves (bodyweight, 70.3 ± 4.2 kg), the pump was inserted and set to its maximal motor speed of 7000 rpm. Blood samples were taken for blood gas analyses, hematology and chemistry on an hourly basis. ANOVA was used for statistical analysis. During the 6-h run, hematocrit and red blood cell count were stable (p = 0.77 and 0.87, respectively). Platelet count was not significantly altered (p = 0.55). LDH was stable (p = 0.61) and plasma free hemoglobin remained below 100 mg/l throughout the experiment. Adequate tissue perfusion was maintained as reflected by the stable mixed venous oxygen saturation (baseline, 72.5 ± 2%, and 6 h, 65.6 ± 3.4%) and no defect of any pump system was detected during this 6-h testing. This right heart minipump appears to have a minimal impact on red cells and platelets when set at its maximal speed for 6 h, underlining the hematological safety of the system.
ACCESSION #
6567716

 

Related Articles

  • Hemodynamic changes during off-pump CABG surgery Do, Quoc-Bao; Goyer, Caroline; Chavanon, Olivier; Couture, Pierre; Denault, André; Cartier, Raymond // European Journal of Cardio-Thoracic Surgery;Mar2002, Vol. 21 Issue 3, p385 

    Objectives: The purpose of this study was to assess the patients'' hemodynamics during off-pump coronary artery bypass graft (OPCABG) surgery. Methods: Continuous monitoring of the mean systemic arterial pressure (SAP), mean pulmonary arterial pressure (PAP), mixed venous oxygen saturation...

  • Measurement of Myocardial Fractional Flow Reserve is a Cost-effective Way to Identify Coronary Artery Lesions of Indeterminate Severity that Warrant Revascularisation Trivedi, Shailendra; Aroney, Constantine N.; Walters, Darren L.; Bett, John Hugh Nicholas // Heart, Lung & Circulation;Dec2005, Vol. 14 Issue 4, p239 

    Background: The RADIâ„¢ pressure wire may be used in stenotic coronary arteries to calculate myocardial fractional flow reserve (FFRmyo), the ratio between distal hyperaemic coronary pressure and aortic pressure. A ratio less than 0.75 categorises lesions of haemodynamic significance for...

  • Anaesthesia for off-pump coronary artery surgery. Hett, David A. // Continuing Education in Anaesthesia, Critical Care & Pain;Apr2006, Vol. 6 Issue 2, p60 

    The article provides information on off-pump coronary artery bypass (OPCAB) surgery technique. The effective local cardiac wall stabilization to allow anastomotic suturing is said to be the key to successful OPCAB surgery. It presents the anaesthetic goals of management of OPCAB surgery which...

  • Prophylactic milrinone during OPCAB of posterior vessels: implication in angina patients taking β-blockers Kim, Jin-Hee; Ham, Byung Moon; Kim, Yong Lak; Bahk, Jae-Hyon; Ryu, Ho-Geol; Jeon, Yoon-Seok; Kim, Ki-Bong // European Journal of Cardio-Thoracic Surgery;Nov2003, Vol. 24 Issue 5, p770 

    Objective: To determine whether a phosphodiesterase type 3 inhibitor can improve hemodynamics during off-pump coronary artery bypass grafting (OPCAB) of posterior vessels in patients on β1-adrenoreceptor blockers. Methods: Thirty patients scheduled for OPCAB of the obtuse marginal artery...

  • Cardiac compression following cardiac surgery due to unrecognised hiatus hernia Devbhandari, Mohan P.; Khan, Mohammad Aamir; Hooper, Timothy L. // European Journal of Cardio-Thoracic Surgery;Nov2007, Vol. 32 Issue 5, p813 

    Abstract: A 76-year-old man who had undergone a routine coronary artery bypass grafting operation developed severe haemodynamic instability in the early postoperative period in spite of multiple inotropic supports. Due to persistent instability of haemodynamics and worsening acidosis his chest...

  • Numerical investigation and identification of susceptible sites of atherosclerotic lesion formation in a complete coronary artery bypass model. Jun-Mei Zhang; Leok Poh Chua; Ghista, Dhanjoo N.; Simon Ching Man Yu; Yong Seng Tan // Medical & Biological Engineering & Computing;Jul2008, Vol. 46 Issue 7, p689 

    As hemodynamics is widely believed to correlate with anastomotic stenosis in coronary bypass surgery, this paper investigates the flow characteristics and distributions of the hemodynamic parameters (HPs) in a coronary bypass model (which includes both proximal and distal anastomoses), under...

  • Effects of preoperative magnesium therapy on arrhythmias and myocardial ischemia during off-pump coronary surgery. Beşoğul, Yavuz; Gemalmaz, Hüseyin; Aslan, Recep // Annals of Thoracic Medicine;Jul2009, Vol. 4 Issue 3, p137 

    BACKGROUND: Heart manipulation during off-pump coronary artery bypass surgery may cause hemodynamic instability, and temporary coronary arterial occlusion may lead to myocardial ischemia. To reduce this, perioperative β-blocking agents or calcium antagonists can be administrated. The effects...

  • Trans-esophageal echocardiography in off-pump coronary artery bypass grafting. Kapoor, Poonam Malhotra; Chowdhury, Ujjwal; Mandal, Banashree; Kiran, Usha; Karnatak, Rajendra // Annals of Cardiac Anaesthesia;Jul2009, Vol. 12 Issue 2, following p176 

    Two features of off-pump coronary artery bypass (OPCAB) can lead to hemodynamic instability: transient occlusion of coronary arteries during distal anastomosis construction and displacement of the heart to provide access to distal coronary arteries. The position of the heart during OPCAB...

  • Life-saving percutaneous coronary intervention in acute occlusion of two saphenous vein grafts. Tomulić, Vjekoslav; Jakljević, Tomislav // Cardiologia Croatica;Mar/Apr2013, Vol. 8 Issue 3/4, p139 

    Introduction: ST elevation myocardial infarction (STEMI in patients after coronary bypass artery graft (CABG) surgery is evenly caused by acute saphenous vein graft (SVG) occlusion (~50%) or native vessel occlusion (~50%). Acute SVG occlusion is infrequent event accounting for 2-3% of primary...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics