TITLE

Body Composition and Coronary Heart Disease Mortality-- An Obesity or a Lean Paradox?

AUTHOR(S)
LAVIE, CARL J.; DE SCHUTTER, ALBAN; PATEL, DHARMENDRA KUMAR; ARTHAM, SURYA M.; MILANI, RICHARD V.
PUB. DATE
September 2011
SOURCE
Mayo Clinic Proceedings;Sep2011, Vol. 86 Issue 9, p857
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVE: To determine the combined effects of body mass Index (BMI) and body fat (BF) on prognosis In coronary heart disease (CHD) to better understand the obesity paradox. PATIENTS AND METHODS: We studied 581. patients with CHD between January 1, 2000, and July 31, 2005, who were divided Into low (<25) and high BM1 (≥25), as well as iow (≥25% men and ≥35% women) and high BF (>25% in men and >35% in women). Four groups were analyzed by total mortailty during the 3-year follow-up by National Death Index: low BF/iow BMI (n=il9), high BF/low BMI (n26), low BF/hlgh BMI (n=125), and high BF/high BMI (n=311). RESULTS: During the 3-year follow-up, mortality was highest In the low BF/low BMI group (11%), which was significantly (P<.001) higher than that in the other 3 groups (3.9%, 3.2%, and 2.6%, re- spectIvely); using the high BF/high BM1 group as a reference, the low BF/low BMI group had a 4.24-fold increase in mortality (con- fidence interval [Cl], 1.76-10.23; P=.001). in multivariate logistic regression for mortality, when entered Individually, both high BMI (odds ratio [OR], 0.79; Cl, 0.69-0.90) and high BF (OR, 0.89; Cl, 0.82-0.95) as continuous variables were Independent predictors of better survival, whereas low BMI (OR, 3.60; Cl, 1.37.9.47) and iow BF (OR, 3.52; Cl, 1.34-9.23) as categorical variables were independent predictors of higher mortality. CONCLUSION: Although both low BF and low BMI are independent predictors of mortality in patients with CHD, only patients with combined iow BF/low BMI appear to be at particularly high risk of mortality during follow-up. Studies are needed to determine optimal body composition in the secondary prevention of CHD.
ACCESSION #
65538139

 

Related Articles

  • The childhood obesity epidemic and coronary artery disease risk.  // Heart;Apr2008, Vol. 94 Issue 4, p536 

    The article focuses on the increasing childhood obesity epidemic and its associated risk, which is the coronary heart disease (CHD). It states that it has been shown that overweight children have risk factors for CHD such as dyslipidaemia, hypertension, impaired glucose tolerance and vascular...

  • Childhood Obesity -- A Looming Disaster. Abrams, Jonathan // Travel Medicine Advisor;Mar2008, Vol. 18 Issue 3, p15 

    This remarkable study is a population analysis of a huge cohort of children in Denmark who were followed, since 1930 or later, for the presence of coronary heart disease (CHD), and had all mandatory annual examinations at schools in Copenhagen. The study analyzed data from 277,000 children, aged...

  • True and true, but not a paradox. Stovitz, Steven D. // Heart;Nov2015, Vol. 101 Issue 22, p1850 

    A letter to the editor is presented regarding the articles published about meta-analysis and a commentary on the relation of mortality and obesity in patients with coronary heart disease (CHD).

  • The State of Obesity Management for Women Giving Birth in Atlantic Canada. Kirk, Sara F. L.; Price, Sheri L.; Penney, Tarra L.; Jarvie, Lorraine; Power, Hilda; Cramm, C. Lisa // Maternal & Child Health Journal;May2010, Vol. 14 Issue 3, p453 

    Objectives The purpose of this survey was to gain insight into the status of birthing facilities across Atlantic Canada regarding obesity management. Specifically, we were interested in learning about the reported number of obese women entering birthing facilities, if body mass index (BMI) was...

  • Body Composition and Abdominal Obesity in Patients With and Without Coronary Heart Disease. Rahmani, Aasghar; Ahmadi, Mohammadreza Hafezi; Misgavam, Samira; Farhadi, Farbod; Shariatpanahi, Zahra Vahdat // Cardiology Research;2014, Vol. 5 Issue 2, p68 

    Background: The body fat and its distribution is an important risk factor for coronary artery diseases. The aim of this study was to evaluate the relationship between body composition and abdominal obesity in patients with and without coronary involvement in stable angina. Methods: One hundred...

  • Childhood obesity predicts cardiovascular disease in adults. Silverstein, Janet H. // Cardiology Today;Jun2008, Vol. 11 Issue 6, p34 

    The article reports that 2 studies demonstrated early coronary artery disease in young adults who had been overweight as adolescents, including the Bogalusa Heart Study and the Cardiovascular Risk In Young Finns study. The first study revealed a correlation between high childhood body mass index...

  • Cross-Sectional Comparisons of BMI and Waist Circumference in British Children: Mixed Public Health Messages. Griffiths, Claire; Gately, Paul; Marchant, Paul R.; Cooke, Carlton B. // Obesity (19307381);Jun2012, Vol. 20 Issue 6, p1258 

    Research suggests that there has been a leveling off in obesity prevalence occurring in the child population. However, a concern with the evidence base is that all of the studies have relied upon the use of BMI. The purpose of this study was to compare waist circumference (WC), BMI, and...

  • BMI Faulted as Obesity Gauge.  // Tufts University Health & Nutrition Letter;Nov2006, Vol. 24 Issue 9, p1 

    The article looks at studies which cast doubt on the reliability of Body Mass Index (BMI), the most common measure of overweight, obesity, and underweight. BMI does not differentiate between body fat and muscle mass. It also does not account for the location of body fat, and studies have show...

  • Image quality and diagnostic accuracy of 16-slice multidetector computed tomography for the detection of coronary artery disease in obese patients. Burgstahler, C.; Beck, T.; Kuettner, A.; Reimann, A.; Kopp, A. F.; Heuschmid, M.; Claussen, C. D.; Schroeder, S. // International Journal of Obesity;Mar2006, Vol. 30 Issue 3, p569 

    Background:Cardiac multislice spiral computed tomography (MSCT) scanners permit visualization of the coronary arteries with an overall good sensitivity (sens) and specificity (spec). However, in obese patients (pts), who are at higher risk to develop coronary artery disease (CAD), image quality...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics