September 2011
American Journal of Health-System Pharmacy;9/1/2011, Vol. 68 Issue 17, p1563
Academic Journal
The article presents clinical updates. The necessity of providing high dosages to treat troublesome pathogens is discussed as standard dosages of antimicrobials fail to provide optimal bactericidal activity against Pseudomonas aeruginosa. A study shows that using warfarin and concomitant ceftriaxone elevated international normalized ratio (INR) values. Aminoglycoside pharmacokinetics may occur in patients with chronic spinal cord injury due to which patient-specific monitoring is recommended.


Related Articles

  • Moxifloxacin--acetaminophen--warfarin interaction during bacille Calmette-Guérin treatment for bladder cancer. Lee, Roy; Wen, Alice; Berube, Caroline // American Journal of Health-System Pharmacy;5/1/2011, Vol. 68 Issue 9, p814 

    Purpose. The case of a patient receiving long-term anticoagulation with warfarin who had supratherapeutic International Normalized Ratios (INRs) after receiving concomitant acetaminophen and moxifloxacin as prophylaxis with bacille Calmette-Guérin (BCG) therapy for bladder cancer is reported....

  • The "Masculine Hormone"- and SCI (Part 1). JOHNSTON, S. LAURANCE // PN;Aug2011, Vol. 65 Issue 8, p24 

    The article offers information on the masculine hormone testosterone and testosterone replacement therapy (TRT). It mentions several aspects concerning testosterone including its production, its transport to target tissues, and the significant levels and level-contributing factors. Furthermore,...

  • Do spinal cord injury patients always get the best treatment for neuropathic bladder after discharge from regional spinal injuries centre? Vaidyanathan, S.; Singh, G.; Soni, B. M.; Hughes, P. L.; Mansour, Paul; Oo, T.; Bingley, J.; Sett, P. // Spinal Cord;Aug2004, Vol. 42 Issue 8, p438 

    OBJECTIVE:: To draw attention to inadequate care received by some spinal cord injury patients after discharge from the regional spinal injury center. SETTING:: Regional Spinal Injuries Centre, Southport, UK. METHODS:: Presence of the urethral stricture was not recognised in a 69-year-old male...

  • Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice.  // Journal of Neuroinflammation;2012, Vol. 9 Issue 1, p40 

    The article presents information on a study conducted on the role of a blockade of interleukin-6 signaling in promoting an alternative pathway of macrophage activation after spinal cord injury (SCI) in mice. In the study, IL-6R monoclonal antibody (MR16-1) antibodies were administered...

  • Ludwig Guttmann and the Paralympic Games. WHITE, EDWARD // Wounds UK;Sep2015, Vol. 11 Issue 3, p109 

    The article focuses on German-born neurologist Professor Sir Ludwig Guttmann and his role in the creation of the Paralympic Games. Guttman is also credited with the establishment of the National Spinal Injuries Centre (NSIC) at Stoke Mandeville in Buckinghamshire, England. The Stoke Mandeville...

  • Elevated International Normalized Ratio values associated with concomitant use of warfarin and ceftriaxone. Clark, Thomas Ross; Burns, Stephanie // American Journal of Health-System Pharmacy;9/1/2011, Vol. 68 Issue 17, p1603 

    Purpose. The case of a patient receiving long-term warfarin therapy who experienced elevated International Normalized Ratio (INR) values on two occasions after injections of ceftriaxone is reported. Summary. An elderly woman (age, 67 years) with multiple comorbidities who had been receiving...

  • Survey on antimicrobial residues in raw milk and antimicrobial use in dairy farms in the Emilia-Romagna region, Italy. Serraino, Andrea; Giacometti, Federica; Marchetti, Giacomo; Zambrini, Angelo V.; Zanirato, Giampaolo; Fustini, Mattia; Rosmini, Roberto // Italian Journal of Animal Science;2013, Vol. 12 Issue 3, p422 

    This survey investigated the antimicrobials most commonly used in dairy herds and antimicrobial residues most frequently detected in milk to evaluate the suitability of rapid screening tests to determine antimicrobial residues in milk. The investigation was carried out in 45 dairy herds...

  • Antibiotics 1973. Plotkin, Stanley A. // Clinical Pediatrics;Nov1973, Vol. 12 Issue 11, p663 

    Discusses the development of new cephalosporins and aminoglycosides in the U.S. Four new licensed cephalosporins; Important antibiotic in the treatment of yeast infections; Other antibiotic introduced.

  • Pharmacodynamic evaluation of i.v. antimicrobials against Pseudomonas aeruginosa samples collected from U.S. hospitals. Keel, Rebecca A.; Kuti, Joseph L.; Sahm, Daniel F.; Nicolau, David P. // American Journal of Health-System Pharmacy;9/1/2011, Vol. 68 Issue 17, p1619 

    Purpose. Selected i.v. antimicrobials were evaluated against Pseudomonas aeruginosa isolates collected from U.S. hospitals to predict the likelihood of achieving maximal bactericidal activity. Methods. The pharmacodynamic profiles of ceftazidime, doripenem, imipenem-cilastatin, levofloxacin,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics