2011 - Candesartan did not improve clinical or functional outcomes in patients with acute stroke and elevated BP
Related Articles
- 2011 - Candesartan did not improve clinical or functional outcomes in patients with acute stroke and elevated BP. Frieden, Rick // ACP Journal Club;6/21/2011, Vol. 154 Issue 6, p4
Question Does candesartan improve clinical or functional outcomes in patients with acute stroke and elevated blood pressure (BP)? Methods Design Randomized placebo-controlled trial (Scandinavian Candesartan Acute Stroke Trial [SCAST]). ClinicalTrials.gov NCT00120003, Current Controlled Trials...
- Management of Hypertension in the Acute Phase of Stroke. Bornes, Troy D.; Butcher, Ken S. // Current Hypertension Reviews;2009, Vol. 5 Issue 1, p24
An increase in arterial blood pressure (BP) is common following the onset of stroke. Although there is evidence suggesting that this acute elevation of BP is associated with a poor clinical outcome in both ischemic and hemorrhagic stroke patients, optimal treatment strategies are currently...
- Management of acute stroke in the elderly: follow-up of a controlled trial. Garraway, W.M.; Akhtar, A.J.; Hockey, L.; Prescott, R.J. // British Medical Journal;9/27/1980, Vol. 281 Issue 6244, p827
Assesses the management of acute stroke in the elderly patients. Factors contributing to the functional outcome; Improvement in the functional outcome in the patients; Continuance of stroke rehabilitation after the acute phase.
- Candesartan not beneficial in patients with acute stroke and raised BP. // Australian Journal of Pharmacy;Aug2011, Vol. 92 Issue 1095, p83
The article reports on a study to evaluate the benefit of angiotensin-receptor blocker candesartan in patients with acute stroke and raised blood pressure (BP). It references "The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled,...
- Blood Pressure and Acute Ischemic Stroke. Hill, Michael D. // Canadian Journal of Neurological Sciences;Mar2011, Vol. 38 Issue 2, p187
The author reflects on the treatment of acute hypertension in patients with acute ischemic stroke, in which limited guidance is available to justify treatment. He cites the study of J. Zhang and colleagues which shows that acute blood pressure (BP) is associated with the clinical outcome. He...
- Induced hypertension for the treatment of acute MCA occlusion beyond the thrombolysis window: case report. Bogoslovsky, Tanya; H�pp�l�, Olli; Salonen, Oili; Lindsberg, Perttu J. // BMC Neurology;2006, Vol. 6, p46
Background: A minority of stroke patients is eligible for thrombolytic therapy. Small pilot case series have hinted that elevation of incident arterial blood pressure might be associated with a favorable prognosis either in acute or subacute stroke. However, these patients were not considered...
- Statin pre-treatment is associated with lower platelet activity and favorable outcome in patients with acute non-cardio-embolic ischemic stroke. // Critical Care;2011, Vol. 15 Issue 3, p303
The article presents a study which analyses the effect of prior statin treatment in reducing neurologic deterioration and functional outcome in acute ischemic stroke patients. The study uses flow cytometry to measure platelet activation markers at different time points after the occurrence of...
- Twenty four hour pulse pressure predicts long term recurrence in acute stroke patients. Tsivgoulis, G.; Spengos, K.; Zakopoulos, N.; Manios, E.; Xinos, K.; Vassilopoulos, D.; Vemmos, K. N. // Journal of Neurology, Neurosurgery & Psychiatry;Oct2005, Vol. 76 Issue 10, p1360
Objectives: The impact of different blood pressure (BP) components during the acute stage of stroke on the risk of recurrent stroke is controversial. The present study aimed to investigate by 24 hour BP monitoring a possible association between acute BP values and long term recurrence. Methods:...
- Blood Pressure and Early Clinical Outcome Among Acute Ischemic Stroke Patients. Jintao Zhang; Ying Peng; Huanqing Fan; Mei Chen; Xu, Tan; Yonghong Zhang // Canadian Journal of Neurological Sciences;Mar2011, Vol. 38 Issue 2, p225
Objectives: The association between blood pressure (BP) and short-term clinical outcome of acute ischemic stroke is inconclusive. We investigated the association between BP in the first 72 hours following admission and death in-hospital and neurologic deficiency at discharge among patients with...


