TITLE

Mosquitocidal properties of nereistoxin against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae)

AUTHOR(S)
Samidurai, Kaliyaperumal; Saravanakumar, Ayyappan
PUB. DATE
October 2011
SOURCE
Parasitology Research;Oct2011, Vol. 109 Issue 4, p1107
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Emergence of resistance among mosquitoes is a recent problem. Safe and eco-friendly agents from biological origins are the need of the hour. Nereistoxin, a naturally occurring substance, was first isolated from the marine annelid Lumbriconereis heteropoda and stored in the freezer. In the present study, the toxicity of nereistoxin was evaluated against vector mosquitoes. The larvicidal, ovicidal and adulticidal activities of nereistoxin were assayed for their toxicity against three important vector mosquitoes, viz., Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae). The nereistoxin was inversely proportional to the concentration and directly proportional to the mosquitoes. The larvicidal activity after 24 h LC value was observed at 0.467, 0.535 and 0.601 ppm for A. stephensi, A. aegypti and C. quinquefasciatus, respectively. The ovicidal activity after 120 h zero percentage of egg hatchability was observed at a concentration of 0.8 ppm for A. stephensi and 1.0 ppm for A. aegypti and C. quinquefasciatus. The results of the adulticidal activity after 24 h LD value were observed at 0.022, 0.028 and 0.034 ppm for A. stephensi, A. aegypti and C. quinquefasciatus, respectively. The extracted nereistoxin was characterized and identified by ultraviolet, infrared, nuclear magnetic resonance, mass spectroscopic methods and high pressure liquid chromatography. These results clearly reveal that the nereistoxin served as a potential larvicidal, ovicidal and adulticidal activity against vector mosquitoes.
ACCESSION #
65454771

 

Related Articles

  • Intricacies, Complexities, and Limitations of Research on Autism Treatments: An Examination of Seven Treatment Approaches. Seitler, Burton Norman // Ethical Human Psychology & Psychiatry;2011, Vol. 13 Issue 2, p155 

    Part 1 of this article, published in Volume 12, Issue 2, probed factors associated with autism. Many of those factors had to do with how toxic substances are polluting our environment. Investigative chicanery involving one neurotoxic agent in particular (thimerosal) was uncovered. The...

  • Human Ntera2 cells as a predictive in vitro test system for developmental neurotoxicity. Stern, Michael; Gierse, Andrea; Tan, Saime; Bicker, Gerd // Archives of Toxicology;Jan2014, Vol. 88 Issue 1, p127 

    Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the '3Rs' (reduction, replacement, and refinement) of animal testing,...

  • Effect of Nitrate, Ammonium and Urea on Growth and Pinnatoxin G Production of Vulcanodinium rugosum. Abadie, Eric; Kaci, Lamia; Berteaux, Tom; Hess, Philipp; Sechet, Véronique; Masseret, Estelle; Rolland, Jean Luc; Laabir, Mohamed // Marine Drugs;2015, Vol. 13 Issue 9, p5642 

    Vulcanodinium rugosum, a recently described dinoflagellate species producing a potent neurotoxin (pinnatoxin G), has been identified in French Mediterranean lagoons and was responsible for recurrent episodes of shellfish toxicity detected by mouse bioassay. Until now, the biology and physiology...

  • Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model. Wang, Min S.; Boddapati, Shanta; Emadi, Sharareh; Sierks, Michael R. // BMC Neuroscience;2010, Vol. 11, p57 

    Background: Overexpression and abnormal accumulation of aggregated a-synuclein (aS) have been linked to Parkinson's disease (PD) and other synucleinopathies. aS can misfold and adopt a variety of morphologies but recent studies implicate oligomeric forms as the most cytotoxic species. Both...

  • Functionally Relevant Domains of the Prion Protein Identified In Vivo. Baumann, Frank; Pahnke, Jens; Radovanovic, Ivan; Rülicke, Thomas; Bremer, Juliane; Tolnay, Markus; Aguzzi, Adriano // PLoS ONE;2009, Vol. 4 Issue 9, p1 

    The prion consists essentially of PrPSc, a misfolded and aggregated conformer of the cellular protein PrPC. Whereas PrPC deficient mice are clinically healthy, expression of PrPC variants lacking its central domain (PrPΔCD), or of the PrP-related protein Dpl, induces lethal neurodegenerative...

  • Chapter 16: Synthesis of New Reactivators of Cholinesterase. Petrova, Iskra; Samnaliev, Ivan; Dishovsky, Christophor // Journal of Medical Chemical, Biological & Radiological Defense;2010, Vol. 8, p115 

    Irrespective of the fact that the main mechanism of toxicity of the nerve agents (tabun, sarin, soman, cyclosarin, VX) - inhibition of acetylcholinesterse (AChE) in peripheral and central nervous systems is very well known there are some unresolved problems related to the antidote treatment of...

  • LEAD POISONING. Rizescu, Cristiana; Cirstea, Elena // Metalurgia International;2008, Vol. 13 Issue 4, p56 

    Lead is a chemical element in the periodic table that has the symbol Pb (Latin: plumbum) and atomic number 82. A soft, heavy, toxic and malleable poor metal, lead is bluish white when freshly cut but tarnishes to dull gray when exposed to air. Lead is used in building construction, lead-acid...

  • Developmental Neurotoxicity of Perfluorinated Chemicals Modeled in Vitro. Slotkin, Theodore A.; MacKillop, Emiko A.; Melnick, Ronald L.; Thayer, Kristina A.; Seidler, Frederic J. // Environmental Health Perspectives;Jun2008, Vol. 116 Issue 6, p716 

    BACKGROUND: The widespread detection of perfluoroalkyl acids and their derivatives in wildlife and humans, and their entry into the immature brain, raise increasing concern about whether these agents might be developmental neurotoxicants. OBJECTIVES: We evaluated perfluorooctane sulfonate...

  • In Vitro Techniques for the Assessment of Neurotoxicity. Harry, G. Jean; Billingsley, Melvin; Bruinink, Arend; Campbell, Iain L.; Classen, Werner; Dorman, David C.; Galli, Corrado; Ray, David; Smith, Robert A.; Tilson, Hugh A. // Environmental Health Perspectives Supplements;Feb98 Supplement 1, Vol. 106, p131 

    Presents a study on in vitro techniques for the assessment of neurotoxicity. Discussion of the strengths and limitations of techniques in their usefulness to identify hazards and the subsequent dose-response assessment; Selection and evaluation of end points used to determine potential...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics