New Findings Detail How a Virus Prepares to Infect Cells

July 2011
International Journal of Virology;2011, Vol. 7 Issue 2, p65
Academic Journal
No abstract available.


Related Articles

  • Target Cell Cyclophilins Facilitate Human Papillomavirus Type 16 Infection. Bienkowska-Haba, Malgorzata; Patel, Hetalkumar D.; Sapp, Martin // PLoS Pathogens;Jul2009, Vol. 5 Issue 7, p1 

    Following attachment to primary receptor heparan sulfate proteoglycans (HSPG), human papillomavirus type 16 (HPV16) particles undergo conformational changes affecting the major and minor capsid proteins, L1 and L2, respectively. This results in exposure of the L2 N-terminus, transfer to uptake...

  • Viral security proteins: counteracting host defences. Agol, Vadim I.; Gmyl, Anatoly P. // Nature Reviews Microbiology;Dec2010, Vol. 8 Issue 12, p867 

    Interactions with host defences are key aspects of viral infection. Various viral proteins perform counter-defensive functions, but a distinct class, called security proteins, is dedicated specifically to counteracting host defences. Here, the properties of the picornavirus security proteins L...

  • Vaccinia Protein F12 Has Structural Similarity to Kinesin Light Chain and Contains a Motor Binding Motif Required for Virion Export. Morgan, Gareth W.; Hollinshead, Michael; Ferguson, Brian J.; Murphy, Brendan J.; Carpentier, David C. J.; Smith, Geoffrey L. // PLoS Pathogens;Feb2010, Vol. 6 Issue 2, p1 

    Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that binds cargo. F12 and KLC share similar size, pI,...

  • Distinct cellular receptor interactions in poliovirus and rhinoviruses. Li Xing; Tjarnlund, Karin; Lindqvist, Birgitta; Kaplan, Gerardo G.; Feigelstock, Dino; Cheng, R. Holland; Casasnovas, Jos� M. // EMBO Journal;3/15/2000, Vol. 19 Issue 6, p1207 

    Receptor binding to human pollovirus type 1 (PV1/M) and the major group of human rhinoviruses (HRV) was studied comparatively to uncover the evolution of receptor recognition in picornaviruses. Surface plasmon resonance showed receptor binding to PV1/M with faster association and dissociation...

  • Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcÉ›RI. Holdom, Mary D.; Davies, Anna M.; Nettleship, Joanne E.; Bagby, Sarah C.; Dhaliwal, Balvinder; Girardi, Enrico; Hunt, James; Gould, Hannah J.; Beavil, Andrew J.; McDonnell, James M.; Owens, Ray J.; Sutton, Brian J. // Nature Structural & Molecular Biology;May2011, Vol. 18 Issue 5, p571 

    Among antibody classes, IgE has a uniquely slow dissociation rate from, and high affinity for, its cell surface receptor FcɛRI. We show the structural basis for these key determinants of the ability of IgE to mediate allergic hypersensitivity through the 3.4-Å-resolution crystal...

  • Roles for accessory molecules in microbial recognition by Toll-like receptors. Miyake, Kensuke // Journal of Endotoxin Research;2006, Vol. 12 Issue 4, p195 

    The Toll family of receptors recognizes a variety of microbial products and triggers immune responses. Recent progress has revealed a requirement for accessory molecules in microbial recognition by Toll-like receptors. Lipopolysaccharide (LPS) recognition requires LPS binding protein (LBP),...

  • Transferrin Receptor. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p658 

    A definition of "transferrin receptor" is presented. It refers to cell membrane receptors for transferrin. They have a role in iron uptake by the cell and are highly expressed in proliferating cells.

  • 823. SLC350F2 Transporter Protein Is the Receptor Targeted by a Library-Selected Retroviral Envelope. Sarangi, Anindita; Bupp, Keith; Roth, Monica J. // Molecular Therapy;Jun2006, Vol. 13, pS319 

    A major limitation of gene therapy is the inability for specific cell types to be targeted for infection by viral vectors. This study shows the first identification of a new retroviral receptor protein, SLC35F2, selected by screening a random library of retroviral Envelope proteins for...

  • A nexus for receptor recycling. Pfeffer, Suzanne R. // Nature Cell Biology;May2013, Vol. 15 Issue 5, p446 

    Sorting nexin proteins (SNXs) and the cargo-selective retromer complex play key roles in receptor recycling from endosomes to the cell surface. A global proteomics analysis reveals a collection of cell surface proteins that rely on SNX27 and the retromer complex for their cell surface...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics