TITLE

Antibiotic resistance in ocular bacterial pathogens

AUTHOR(S)
Sharma, S
PUB. DATE
July 2011
SOURCE
Indian Journal of Medical Microbiology;Jul2011, Vol. 29 Issue 3, p218
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Bacterial infections of the eye are common and ophthalmologists are spoilt for choice with a variety of antibiotics available in the market. Antibiotics can be administered in the eye by a number of routes; topical, subconjunctival, subtenon and intraocular. Apart from a gamut of eye drops available, ophthalmologists also have the option of preparing fortified eye drops from parenteral formulations, thereby, achieving high concentrations; often much above the minimum inhibitory concentration (MIC), of antibiotics in ocular tissues during therapy. Antibiotic resistance among ocular pathogens is increasing in parallel with the increase seen over the years in bacteria associated with systemic infections. Although it is believed that the rise in resistant ocular bacterial isolates is linked to the rise in resistant systemic pathogens, recent evidence has correlated the emergence of resistant bacteria in the eye to prior topical antibiotic therapy. One would like to believe that either of these contributes to the emergence of resistance to antibiotics among ocular pathogens. Until recently, ocular pathogens resistant to fluoroquinolones have been minimal but the pattern is currently alarming. The new 8-fluoroquinolone on the scene-besifloxacin, is developed exclusively for ophthalmic use and it is hoped that it will escape the selective pressure for resistance because of lack of systemic use. In addition to development of new antibacterial agents, the strategies to halt or control further development of resistant ocular pathogens should always include judicious use of antibiotics in the treatment of human, animal or plant diseases.
ACCESSION #
65286914

 

Related Articles

  • Risk Factors for Late-Onset Group B Streptococcal Disease Before and After Implementation of Universal Screening and Intrapartum Antibiotic Prophylaxis. Pintye, Jillian; Saltzman, Babette; Wolf, Elizabeth; Crowell, Claudia S. // Journal of the Pediatric Infectious Diseases Society;Dec2016, Vol. 5 Issue 4, p431 

    Background. It is unclear whether risk factors for late-onset Group B Streptococcus disease (LOD) have changed since the introduction of universal screening and treatment in 2002. Methods. We conducted a case-control study using linked birth certificates and hospital discharge records. All...

  • Physical compatibility of 4% sodium citrate with selected antimicrobial agents. Dotson, Bryan; Lynn, Scarlett; Savakis, Katherine; Churchwell, Mariann D. // American Journal of Health-System Pharmacy;7/15/2010, Vol. 67 Issue 14, p1195 

    Purpose. The physical compatibility of 4% sodium citrate with vancomycin, gentamicin, tobramycin, daptomycin, and linezolid was evaluated. Methods. Admixtures were prepared by mixing 4% sodium citrate with clinically relevant concentrations of antimicrobial agents (vancomycin 5 mg/mL, vancomycin...

  • Antibacterial Effect of Honey on Staphylococci Species Isolated from Animals and Humans. Fiţ, Nicodim; Răpuntean, Gheorghe; Pantrea, Stanca Lucia; Nadăţ, George; Chirilă, Flore; Roba, Dana; Ştefan, Andrei; Criste, Adriana // Bulletin of the University of Agricultural Sciences & Veterinary;2009, Vol. 66 Issue 1, p302 

    The inhibitory and bactericide effect of 4 sort of honey (forest honey, poly-flower honey, linden tree honey and acacia honey) on some staphylococci species (Staphylococcus aureus 4 strains, Staphylococcus intermedius, Staphylococcus xilosus, Staphylococcus hominis, Staphylococcus chromogenes...

  • Preseptal cellulitis caused by Acinetobacter lwoffi. Mathews, Divya; Mathews, John P.; Kwartz, Jeff; Inkster, Clare // Indian Journal of Ophthalmology;Sep2005, Vol. 53 Issue 3, p213 

    Presents a letter to the editor about the treatment of a patient with Acinetobacter Lwoffi causing preseptal cellulitis.

  • Asymptomatic bacteriuria in elderly persons: treat or do not treat? Boscia, Jerome A.; Abrutyn, Elias; Kaye, Donald; Boscia, J A; Abrutyn, E; Kaye, D // Annals of Internal Medicine;May87, Vol. 106 Issue 5, p764 

    Discusses an epidemiologic study of bacteriuria in an elderly population. Complications of bacteriuria; Association between bacteriuria and decreased survival in elderly persons; Efficacy of antimicrobial therapy for asymptomatic bacteriuria.

  • Antibiyotiklerde direnç sorunu. Somer, Ayper // Turkish Pediatrics Archive / Turk Pediatri Arsivi;jun2010 supplement, Vol. 45, p45 

    The treatment of bacterial infections is very complicated by the ability of bacteria to develop resistance to antimicrobial agents. Bacterial resistance results in treatment failure, inadequate empiric antibacterial therapy, the spread of resistant bacteria within the hospital and community,...

  • Science, Control, and the Seemingly Uncontrollable. Bush, Laura // BioPharm International;Aug2006, Vol. 19 Issue 8, p12 

    The article offers information on phage therapy, and discusses its challenges in the present time. Phage Therapy is the therapeutic use of lytic bacteriophages to treat pathogenic bacterial infections. It is an alternative to antibiotics, being developed for clinical use by many western research...

  • Levofloxacin: A Review of its Use in the Treatment of Bacterial Infections in the United States. Croom, Katherine F.; Goa, Karen L. // Drugs;2003, Vol. 63 Issue 24, p2769 

    Levofloxacin (Levaquin[sup ®]) is a fluoroquinolone antibacterial agent with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and atypical respiratory pathogens. It is active against both penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae....

  • Varicella-Related Hospitalization In Children: A Retrospective Study In The Pre-Vaccine Era In Ankara, Turkey. Belet, Nurşen; Tapısız, Anıl; Çiftçi, Ergin; İnce, Erdal; Doğru, Ülker // Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi;Mar2009, Vol. 3 Issue 1, p1 

    Aim: Varicella is predominantly a childhood disease in non-vaccinated populations. The purpose of the study is to evaluate the indications of hospital admissions, complications of varicella infection and their clinical characteristics among previously healthy and children. with underlying...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics