Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function

January 2011
Retrovirology;2011, Vol. 8 Issue 1, p60
Academic Journal
The article presents information on a method to explore proteome that is associated with the nuclear HIV-1 RNAs. The core of the method is generation of cell lines with an integrated provirus that carry RNA binding sites for MS2 bacteriophage protein. The study exploited a method to identify MATR3 as cellular cofactor of Rev activity.


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