TITLE

Altered placental development in undernourished rats: role of maternal glucocorticoids

PUB. DATE
January 2011
SOURCE
Proteome Science;2011, Vol. 9 Issue 1, p105
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports on a study on the role of maternal stress-induced glucocorticoids (GCs) in fetal intrauterine growth restriction (IUGR) and the ensuing risk of adult metabolic syndrome. It also focuses on the placental responses to maternal undernutrition (MUN)-induced maternal stress, which during pregnancy may lead to fetal intrauterine growth restriction (IUGR). The results show that MUN dams displayed significantly increased plasma corticosterone levels compared to control dams.
ACCESSION #
65255421

 

Related Articles

  • A Calcium-Deficient Diet in Rat Dams during Gestation and Nursing Affects Hepatic 11β-hydroxysteroid dehydrogenase-1 Expression in the Offspring. Takaya, Junji; Yamanouchi, Sohsaku; Kaneko, Kazunari // PLoS ONE;Jan2014, Vol. 9 Issue 1, p1 

    Background: Prenatal malnutrition can affect the phenotype of offspring by changing epigenetic regulation of specific genes. Several lines of evidence demonstrate that calcium (Ca) plays an important role in the pathogenesis of insulin resistance syndrome. We hypothesized that pregnant female...

  • Nutrition and growth before birth. Harding, J. E. // Asia Pacific Journal of Clinical Nutrition;2003 Supplement, Vol. 12, pS28 

    Background - It has long been known that babies born small are at increased risk of dying before or immediately after birth. They are also at high risk of infection, lung disease and poor growth, and of adverse developmental outcomes. We now know that these small babies are also at increased...

  • The Role of Maternal Dietary Proteins in Development of Metabolic Syndrome in Offspring. Jahan-Mihan, Alireza; Rodriguez, Judith; Christie, Catherine; Sadeghi, Marjan; Zerbe, Tara // Nutrients;2015, Vol. 7 Issue 11, p9185 

    The prevalence of metabolic syndrome and obesity has been increasing. Pre-natal environment has been suggested as a factor influencing the risk of metabolic syndrome in adulthood. Both observational and experimental studies showed that maternal diet is a major modifier of the development of...

  • Complicaciones maternas y neonatales en una mujer gestante con derivación biliopancreática. Ocón, J.; Sallán, L. // Nutricion Hospitalaria;ene/feb2010, Vol. 25 Issue 1, p120 

    Biliopancreatic diversion (BPD) is a bariatric technique which can lead to the development of nutritional complications such as protein-calorie malnutrition and deficiencies in fat-soluble vitamins. Many women in childbearing age undergone DBP, pregnancy frequently occurs afterwards. Vitamin A...

  • Excessive glucocorticoid exposure during late intrauterine development modulates the expression of cardiac uncoupling proteins in adult hypertensive male offspring. Langdown, Maria L.; Smith, Nicholas D.; Sugden, Mary C.; Holness, Mark J. // Pflugers Archiv European Journal of Physiology;May2001, Vol. 442 Issue 2, p248 

    We investigated the impact of intrauterine growth retardation and fetal programming of hypertension by maternal dexamethasone treatment on cardiac uncoupling protein (UCP) expression during development and in adulthood in the rat. Dexamethasone administered via an indwelling osmotic pump (100...

  • Alteraciones en la nutrición fetal y en las etapas tempranas de la vida. Su repercusión sobre la salud en edades posteriores. Perea-Martínez, Arturo; López-Navarrete, Gloria Elena; Carbajal-Rodríguez, Luis; Rodríguez-Herrera, Raymundo; Zarco-Román, Jorge; Loredo-Abdalá, Arturo // Acta Pediatrica de Mexico;ene/feb2012, Vol. 33 Issue 1, p26 

    Obesity is a universal problema which affects all ages. It increases signigicantly in pregnant women. There is consistent epidemiological evidence that some adverse perinatal conditions are associated to a high risk for a future metabolic syndrome and related problems. Fetal programming and...

  • Neuronal Plasticity in the Entorhinal Cortex. Chapman, C. Andrew; Jones, Roland S. G.; Min Jung // Neural Plasticity;2008, Vol. 2008, Special section p1 

    The article discusses various reports published within the issue, including one by Li Ma et al on the mechanisms of long-term synaptic plasticity and another one by Alejandro Hernández et al on the effect of prenatal malnutrition on the capacity of the entorhinal cortex (EC) to express...

  • Pregnancy in the underweight woman.  // British Medical Journal;5/10/1980, Vol. 280 Issue 6224, p1154 

    Focuses on the maternal and fetal outcome of pregnancy of an underweight woman. Risk of giving birth to an underweight infant; Inadequacy of the infant growth with evidence of delayed neurological development; Importance of the nutritional state of the mother for the health of the infant.

  • Rodzinny niedobór glikokortykosteroidów. Mazur, Artur; Ostański, Mariusz; Kalina, Maria // Pediatric Endocrinology, Diabetes & Metabolism;2007, Vol. 13 Issue 2, p91 

    Familial glucocorticoid deficiency (FOD) is a rare autosomal recessive disorder, in 40% of patients caused by mutation in the ACTH receptor gene. In the remaining affected persons most probably mutation refers to regulatory region of ACTH receptor or other factors responsible for differentiation...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics