TITLE

A model for the Escherichia coli FtsB/FtsL/FtsQ cell division complex

PUB. DATE
January 2011
SOURCE
BMC Structural Biology;2011, Vol. 11 Issue 1, p28
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study developing a structural model of the periplasmic part of the Escherichia coli FtsB/FtsL/FtsQ complex by using bioinformatics tools and experimental data which have been reported in the medical literature. The study found that due to the stability and the important number of hydrophobic residues accessible at the surfaces exposed to the solvent, the proposed FtsB/FtsL/FtsQ complex models are plausible.
ACCESSION #
65255362

 

Related Articles

  • Structural basis for the topological specificity function of MinE. King, Glenn F.; Shih, Yu-Ling; Maciejewski, Mark W.; Bains, Naresh P.S.; Pan, Borlan; Rowland, Susan L.; Mullen, Gregory P.; Rothfield, Lawrence I. // Nature Structural Biology;Nov2000, Vol. 7 Issue 11, p1013 

    Correct positioning of the division septum in Escherichia coli depends on the coordinated action of the MinC, MinD and MinE proteins. Topological specificity is conferred on the MinCD division inhibitor by MinE, which counters MinCD activity only in the vicinity of the preferred midcell division...

  • The Min system is not required for precise placement of the midcell Z ring in Bacillus subtilis. Migocki, Margaret D.; Freeman, Marcelle K.; Wake, R. Gerry; Harry, Elizabeth J. // EMBO Reports;Dec2002, Vol. 3 Issue 12, p1163 

    In bacteria, the Min system plays a role in positioning the midcell division site by inhibiting the formation of the earliest precursor of cell division, the Z ring, at the cell poles. However, whether the Min system also contributes to establishing the precise placement of the midcell Z ring is...

  • Cell Division Gene Cluster in Spiroplasma kunkelii: Functional Characterization of ftsZ and the First Report of ftsA in Mollicutes. Yan Zhao; Hammond, Rosemarie W.; Ing-Ming Lee; Roe, Bruce A.; Shaoping Lin; Davis, Robert E. // DNA & Cell Biology;Feb2004, Vol. 23 Issue 2, p127 

    Spiroplasma kunkelii is a helical, wall-less bacterium that causes corn stunt disease. In adaptation to its phloem-inhabiting parasitic lifestyle, the bacterium has undergone a reductive evolutionary process and, as a result, possesses a compact genome with a gene set approaching the minimal...

  • Colicin A binds to a novel binding site of TolA in the Escherichia coli periplasm. Penfold, Christopher N.; Chan Li; Ying Zhang; Vankemmelbeke, Mireille; James, Richard // Biochemical Society Transactions;Dec2012, Vol. 40 Issue 6, p1469 

    Colicins are protein antibiotics produced by Escherichia coli to kill closely related non-identical competing species. They have taken advantage of the promiscuity of several proteins in the cell envelope for entry into the bacterial cell. The Tol-Pal system comprises one such ensemble of...

  • Selected Amplification of the Cell Division Genes ftsQ-ftsA-ftsZ in Escherichia coli. Vinella, Daniel; Cashel, Michael // Genetics;Dec2000, Vol. 156 Issue 4, p1483 

    Examines the selected amplification of cell division genes in Escherichia coli. Restoration of division in the absence of penicillin-binding protein 2 activity; Identification of operon regulators among mecillinam-resistant mutants; Cause and production of gene duplication and genetic...

  • Characterization of the Porphyromonas gingivalis FtsZ Containing a Novel GTPase Activity. Akifusa, Sumio; Ansai, Toshihiro; Yu, Weixian; Wachi, Masaaki; Nagai, Kazuo; Takehara, Tadamichi // Current Microbiology;Apr2002, Vol. 44 Issue 4, p267 

    The FtsZ protein is a GTPase that is essential for cell division. We have cloned, sequenced, and expressed the FtsZ (PgFtsZ) gene from the Porphyromonas gingivalis, an oral, anaerobic, rod-shaped bacterium implicated in progressive periodontal disease. The PgFtsZ gene consisted of 1374 bp and...

  • Effects of disruption of heat shock genes on susceptibility of Escherichia coli to fluoroquinolones. Yamaguchi, Yuko; Tomoyasu, Toshifumi; Takaya, Akiko; Morioka, Mizue; Yamamoto, Tomoko // BMC Microbiology;2003, Vol. 3, p1 

    Background: It is well known that expression of certain bacterial genes responds rapidly to such stimuli as exposure to toxic chemicals and physical agents. It is generally believed that the proteins encoded in these genes are important for successful survival of the organism under the hostile...

  • A genetic bistable switch utilizing nonlinear protein degradation. Huang, Daniel; Holtz, William J; Maharbiz, Michel M // Journal of Biological Engineering;2012, Vol. 6 Issue 1, p9 

    Background: Bistability is a fundamental property in engineered and natural systems, conferring the ability to switch and retain states. Synthetic bistable switches in prokaryotes have mainly utilized transcriptional components in their construction. Using both transcriptional and enzymatic...

  • Single-cell time-lapse analysis of depletion of the universally conserved essential protein YgjD. Bergmiller, Tobias; Peña-Miller, Rafael; Boehm, Alexander; Ackermann, Martin // BMC Microbiology;2011, Vol. 11 Issue 1, p118 

    Background: The essential Escherichia coli gene ygjD belongs to a universally conserved group of genes whose function has been the focus of a number of recent studies. Here, we put ygjD under control of an inducible promoter, and used time-lapse microscopy and single cell analysis to investigate...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics