Use of Metformin in the Setting of Mild-to-Moderate Renal Insufficiency

June 2011
Diabetes Care;Jun2011, Vol. 34 Issue 6, p1431
Academic Journal
The article offers information on the use of metformin in patients with renal insufficiency. It cites the advantages of metformin including reduced cardiovascular morbidity and total mortality in newly diagnosed type 2 diabetic patients. Metformin was developed for lowering glucose in the 1950s and belongs to the biguanide drug class. Also included are clinical practice guidelines, its pharmacokinetics, the use of metformin in chronic kidney disease (CKD), and progression of CKD in diabetics.


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