TITLE

Clinical Features of Ocular Toxoplasmosis in Korean Patients

AUTHOR(S)
Young-Hoon Park; Jae-Hyung Han; Ho-Woo Nam
PUB. DATE
June 2011
SOURCE
Korean Journal of Parasitology;Jun2011, Vol. 49 Issue 2, p167
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5± 13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retino-choroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.
ACCESSION #
64754397

 

Related Articles

  • Study the Anti-Toxoplasma Antibodies (IgG and IgM) in Hemodialysis Patients of Abadan and Khoramshahr Cities Southwest Iran in 2011 using ELISA. Maraghi, Sharif; Yadyad, Mohammad Jafar; Sheikhi, Marjan; Shamakhteh, Fatemeh; Latifi, Seyed Mahmood // Jundishapur Journal of Microbiology;Sep2013, Vol. 6 Issue 7, p1 

    Background: Toxoplasmosis is a worldwide disease caused by an obligate intracellular protozoan, Toxoplasma gondii and can cause severe infections in immune- compromised individuals. Objectives: The aim of this study was to determinate the anti- Toxoplasma antibodies in hemodialysis patients of...

  • Toxoplasma gondii and schizophrenia. Mokhtari, Mojgan; Mokhtari, Mohammadreza // Annals of General Psychiatry;2006 Supplement 1, Vol. 5, pS169 

    A conference paper on the relation between schizophrenia and toxoplasma gondii in Iranian patients is presented. Serum samples of 230 cases of schizophrenia and 230 of a matched control group were examined for Toxoplasma antibodies by enzyme-linked immunosorbent assay method. Results reveal that...

  • Toxoplasmosis Can Test Diagnostic Skills. Wertheim, Michael S.; Smith, Justine R.; Cunningham Jr., Emmett T.; Regillo, Carl // Review of Ophthalmology;Oct2004, Vol. 11 Issue 10, p140 

    The article reports that both the diagnosis and treatment options of Toxoplasmosis is a test for clinicians. Toxoplasmosis is an infection caused by the parasite toxoplasma gondii, which exists in three major forms: the oocyst, the tachyzoite or infectious form, and the tissue cyst or latent...

  • Ocular Toxoplasmosis in the United States: Recent and Remote Infections. Jones, Jeffrey L.; Bonetti, Valerie; Holland, Gary N.; Press, Cindy; Sanislo, Steven R.; Khurana, Rahul N.; Montoya, Jose G. // Clinical Infectious Diseases;Jan2015, Vol. 60 Issue 2, p271 

    We tested all samples from patients with ocular toxoplasmosis sent to the Palo Alto Medical Foundation Toxoplasma Reference Laboratory from June 2004 through August 2010 for serologic evidence of recent Toxoplasma gondii infection. Of 205 patients aged 10–96 years, 11.7% had recent...

  • Seroepidemiology of toxoplasma gondii in pregnant women: An empirical investigation. Ghanbari Andarieh, Maryam // HealthMed;2014, Vol. 8 Issue 4, p540 

    Toxoplasma is an intracellular protozoan which exists common in both humans and animals. Toxoplasma gondii infection in individuals with healthy immune systems is asymptomatic or with minor symptoms causing permanent immunity against infection. However, it can be transmitted to the fetus through...

  • Antibody response of HIV-infected patients to latent, cerebral and recently acquired toxoplasmosis. Machala, L.; Malý, M.; Hrdá, Š.; Rozsypal, H.; Staňková, M.; Kodym, P. // European Journal of Clinical Microbiology & Infectious Diseases;Feb2009, Vol. 28 Issue 2, p179 

    The aim of this longitudinal study with 626 HIV-infected patients was to evaluate the capability of serological tests in diagnosing the presence of Toxoplasma gondii infection in HIV-infected patients, as well as the potential impact of various treatment regimes on serological results. Low IgG...

  • TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients. Mahner, Sven; Woelber, Linn; Eulenburg, Christine; Schwarz, Joerg; Carney, Walter; Jaenicke, Fritz; Milde-Langosch, Karin; Mueller, Volkmar // BMC Cancer;2010, Vol. 10, p139 

    Background: Angiogenesis appears to play an important role in ovarian cancer. Vascular endothelial growth factor (VEGF) has recently been implicated as a therapeutic target in ovarian cancer. The tissue inhibitor of metalloproteinase 1 (TIMP-1) is involved in tissue invasion and angiogenesis....

  • The Rate of Helicobacter pylori Seropositivity in a Group of Korean Patients with HLA-B27-Associated Acute Anterior Uveitis. Bae, Jeong Hun; Kim, Joon Mo // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1 

    Purpose: To investigate an association between Helicobacter pylori seropositivity and HLA-B27-positive acute anterior uveitis (AAU) in Korean patients. Methods: Retrospective analysis was performed with data from 106 patients previously diagnosed with AAU without clinical evidence of...

  • A protein microarray immunoassay for the serological evaluation of the antibody response in vertically transmitted infections. Ardizzoni, A.; Capuccini, B.; Baschieri, M.; Orsi, C.; Rumpianesi, F.; Peppoloni, S.; Cermelli, C.; Meacci, M.; Crisanti, A.; Steensgaard, P.; Blasi, E. // European Journal of Clinical Microbiology & Infectious Diseases;Sep2009, Vol. 28 Issue 9, p1067 

    The detection of specific serum antibodies is mainly achieved by enzyme-linked immunosorbent assay (ELISA). Here, we describe the setting up of a microarray-based serological assay to screen for IgG and IgM against vertically transmitted pathogens ( Toxoplasma gondii, rubella virus,...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics