Determinants of the DNA-Binding Specificity of the Avian Homeodomain Protein, AKR
- Expression of Ceruloplasmin Pseudogene in Cultured Human Cells. Vasin, A. V.; Platonova, N. A.; Klotchenko, S. A.; Tsymbalenko, N. V.; Puchkova, L. V. // Doklady Biochemistry & Biophysics;Jul/Aug2004, Vol. 397 Issue 1-6, p254
Presents a study which examined the expression of ceruloplasmin (Cp) pseudogene in cultured human cells. Purpose and function of Cp in the body; Information on the process of transporting iron in cell compartments; Analysis of Cp-like protein in mammalian mitochondria.
- ESCRTing intraluminal vesicle formation. Chenette, Emily J. // Nature Cell Biology;May2014, Vol. 16 Issue 5, p400
The article presents information on a study conducted on endosomal sorting complex required for transport (ESCRT) proteins involved in the formation of intraluminal vesicles (ILVs), which states that ESCRT-III proteins wrap around the forming ILVs to facilitate membrane scission.
- TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration. Rousseau, Adrien; McEwen, Alastair G.; Poussin-Courmontagne, Pierre; Rognan, Didier; Nominé, Yves; Rio, Marie-Christine; Tomasetto, Catherine; Alpy, Fabien // PLoS Biology;Dec2013, Vol. 11 Issue 12, p1
: The cancer-associated TRAF4 protein has a TRAF domain that is a bona fide phosphoinositide-binding domain and involved in the modulation of tight junctions and cell migration.
- Probing the importance and potential roles of the binding of the PH-domain protein Boi1 to acidic phospholipids. Hallett, Mark A.; Lo, H. Shuen; Bender, Alan // BMC Cell Biology;2002, Vol. 3, p16
Background: The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src homology 3) domain. Previously, we gained evidence that a PH domain-bearing segment of Boi1, which we call Boi1-PH, is sufficient and...
- The many faces of filamin: A versatile molecular scaffold for cell motility and signalling. Yuanyi Feng; Walsh, Christopher A. // Nature Cell Biology;Nov2004, Vol. 6 Issue 11, p1034
Filamins were discovered as the first family of non-muscle actin-binding protein. They are lage cytoplasmic proteins that cross-link cortical actin into a dynamic three-dimensional structure. Filamins have also been reported to interact with a large number of cellular proteins of great...
- Differential Regulation of Adhesion Complex Turnover by ROCK1 and ROCK2. Lock, Frances E.; Ryan, Katie R.; Poulter, Natalie S.; Parsons, Maddy; Hotchin, Neil A. // PLoS ONE;Feb2012, Vol. 7 Issue 2, p1
Background: ROCK1 and ROCK2 are serine/threonine kinases that function downstream of the small GTP-binding protein RhoA. Rho signalling via ROCK regulates a number of cellular functions including organisation of the actin cytoskeleton, cell adhesion and cell migration. Methodology/Principal...
- CELL BIOLOGY - IMMUNOLOGY - PATHOLOGY The roles of IGF-I and IGFBP-3 in the regulation of proximal tubule, and renal cell carcinoma cell proliferation. Cheung, Catherine W.; Vesey, David A.; Nicol, David L.; Johnson, David W. // Kidney International;Apr2004, Vol. 65 Issue 4, p1272
The roles of IGF-I and IGFBP -3 in the regulation of proximal tubule, and renal cell carcinoma cell proliferation. Background. Insulin-like growth factor I (IGF-I), a potent proximal tubule cell (PTC) mitogen, has been implicated in the progression of many human cancers. Our previous work on...
- HISTOPATHOLOGICAL AND CYTOLOGICAL ANALYSIS OF TRANSMISSIBLE VENEREAL TUMOR IN DOGS AFTER TWO TREATMENT PROTOCOLS. Aguena Sales Lapa, Fabiana; Franco Andrade, Silvia; Gervazoni, Eduardo Roberto; Massumi Kaneko, Vanessa; Carvalho Sanches, Osimar; Almeida Gabriel Filho, Luis Roberto // Colloquium Agrariae;jan-jun2012, Vol. 8 Issue 1, p36
The transmissible venereal tumor (TVT) is a contagious neoplasm of round cells that frequently affect dogs. The treatment consists of chemotherapy being more effective the vincristine alone, however the resistance emergence to this agent due multidrug resistance of the P-glycoprotein (P-gp), a...
- Localization of selenium-binding protein at the tips of rapidly extending protrusions. Miyaguchi, Katsuyuki // Histochemistry & Cell Biology;May2004, Vol. 121 Issue 5, p371
Cell protrusive motility underlies cell fundamental biological processes such as cell growth, locomotion, and migration. Here I showed that selenium-binding protein (SBP) was exclusively located at the leading edges of rapidly growing protrusions in newly plated T98G glioma cells, and at the...