Growth Arrest of Melanoma Cells Is Differentially Regulated by Contact Inhibition and Serum Deprivation
- Evaluation of Albuminated Curcumin as Soluble Drug Form to Control Growth of Cancer Cells in Vitro. Thomas, Christina; Pillai, Lakshmi Sreedharan; Krishnan, Lissy // Journal of Cancer Therapy;Jun2014, Vol. 5 Issue 7, p723
Curcumin (Curc) is well known for its anticancer activity, but its poor solubility in aqueous medium is a major concern for little therapeutic outcome. Therefore, the effort to improve its bioavailability is a major research interest. The current study aimed at conjugation of Curc to serum...
- Modification of MCF-10A Cells with Pioglitazone and Serum-Rich Growth Medium Increases Soluble Factors in the Conditioned Medium, Likely Reducing BT-474 Cell Growth. Khoo, Boon Yin; Miswan, Noorizan; Balaram, Prabha; Nadarajan, Kalpanah; Elstner, Elena // International Journal of Molecular Sciences;May2012, Vol. 13 Issue 5, p5607
In the present study, we aimed to preincubate MCF-10A cells with pioglitazone and/or serum-rich growth media and to determine adhesive and non-adhesive interactions of the preincubated MCF-10A cells with BT-474 cells. For this purpose, the MCF-10A cells were preincubated with pioglitazone and/or...
- Inhibition effects of protein-conjugated amorphous zinc sulfide nanoparticles on tumor cells growth. Cao, Ying; Wang, Hua-Jie; Cao, Cui; Sun, Yuan-Yuan; Yang, Lin; Wang, Bao-Qing; Zhou, Jian-Guo // Journal of Nanoparticle Research;Jul2011, Vol. 13 Issue 7, p2759
In this article, a facile and environmentally friendly method was applied to fabricate BSA-conjugated amorphous zinc sulfide (ZnS) nanoparticles using bovine serum albumin (BSA) as the matrix. Transmission electron microscopy analysis indicated that the stable and well-dispersed nanoparticles...
- Tumour cells can mend their ways. Mozdy, Amy Davis // New Scientist;04/12/97, Vol. 154 Issue 2077, p17
Reveals that cancerous cells can be forced to behave like normal cells by fine-tuning their chemical communication with the environment. Implications for breast cancer research; Results of study conducted Mina Bissel and Valerie Weaver of the Lawrence Berkeley National Laboratory in California.
- Vegetables and fruits are good for you! // Countryside & Small Stock Journal;Nov/Dec2000, Vol. 84 Issue 6, p112
Features a study by the University of Wisconsin-Madison on the effects of the small concentrations of plant compounds on the growth of human cancer cells.
- Breast cancer update: Reducing your risk. Kuzemchak, Sally // Shape;Aug98, Vol. 17 Issue 12, p28
Reports that according to a study conducted by the United States Department of Defense, revealed that women who are more exposed to sunshine can slow the rate of cancer cell growth. Indication that vitamin D-rich foods can be used by persons who are not exposed to sunlight; Reference to some of...
- Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis. Schempp, Christoph M.; Kirkin, Vladimir; Simon-Haarhaus, Birgit; Kersten, Astrid; Kiss, Judit; Termeer, Christian C.; Gilb, Bernhard; Kaufmann, Thomas; Borner, Christoph; Sleeman, Jonathan P.; Simon, Jan C. // Oncogene;2/14/2002, Vol. 21 Issue 8, p1242
Presents a study that examined the role of hyperforin in inhibiting the growth of tumor cells by induction of apoptosis. Characteristics of apoptosis; Phases in the process of apoptosis; Causes of caspase activation; List of cytotoxic drugs.
- Dipyridamole potentiates the in vitro activity of MTA (LY231514) by inhibition of thymidine transport. Smith, P G; Marshman, E; Newell, D R; Curtin, N J // British Journal of Cancer;2/15/2000, Vol. 82 Issue 4, p924
The novel pyrrolopyrimidine-based antifolate LY231514 (MTA), inhibits multiple folate-requiring enzymes including thymidylate synthase, glycinamide ribonucleotide formyltransferase and dihydrofolate reductase. Both thymidine and hypoxanthine are required to reverse MTA growth inhibition in...
- The Metastatic Process. // Radiation Therapist;Spring2009, Vol. 18 Issue 1, p34
A quiz concerning metastasis is presented.