Genomic Organization of Mouse Gene zfp162
- Of mice and men. Coghlan, Andy; Cohen, Philip // New Scientist;12/7/2002, Vol. 176 Issue 2372, p12
Focuses on a draft sequence of a mouse genome that was published in the periodical 'Nature.' Significance of the draft for the scope of human research; Goal of the mouse genome project; Difference between genes of mice and humans for smell, immunity and reproduction; Number of human genes...
- Shotgun sample sequence comparisons between mouse and human genomes. Bouck, John B.; Metzker, Michael L.; Gibbs, Richard A. // Nature Genetics;May2000, Vol. 25 Issue 1, p31
A mixed 'clone-by-clone' and 'whole-genome shotgun' strategy will be used to determine the genomic sequence of the mouse. This method will allow a phase of rapid annotation of the contemporaneous human sequence draft, through whole-genome 'sample sequence comparisons'.
- Question 11An investigator has identified and cloned a human gene, but no corresponding mouse ortholog has yet been identified. How can a mouse genomic sequence with similarity to the human gene sequence be retrieved? // Nature Genetics;Sep2003 Supplement, Vol. 35, p63
Presents information regarding Web browsers to retrieve a mouse genomic sequence with similarity to the human gene sequence. Location of human gene sequence using University of California in Santa Cruz, California (UCSC) genome browser; Facility of providing hyperlinks to the mouse genomic...
- Mining the mouse genome. Bradley, Allan // Nature;12/5/2002, Vol. 420 Issue 6915, p512
Explores the research significance of mouse genome sequencing. Reasons why the mouse has emerged as the pre-eminent model organism; Existence of non-coding regions of sequence that are identical to their counterparts in the human genome; Potential for mining mutation data, phenotype information...
- the mouse genome. // Nature;12/5/2002, Vol. 420 Issue 6915, p510
Presents a timeline that charts the key events that led to the publication of the mouse genome sequence. Evolution of the mouse; Use of mice for laboratory experiments; Creation of the first computer database for mouse genetics; Production of the first transgenic mice.
- Human biology by proxy. Gunter, Chris; Dhand, Ritu // Nature;12/5/2002, Vol. 420 Issue 6915, p509
Introduces a series of papers on the sequencing of the mouse genome, published in the December 5, 2002 issue of the scientific journal 'Nature.' Overview of the future of mouse genetics and genomics; Transcription units; Comparison of sequences of the human chromosome 21 in mice with their...
- Probabilistic whole-genome alignments reveal high indel rates in the human and mouse genomes. // Bioinformatics;Jul2007, Vol. 23 Issue 13, pi289
Motivation: The two mutation processes that have the largest impact on genome evolution at small scales are substitutions, and sequence insertions and deletions (indels). While the former have been studied extensively, indels have received less attention, and in particular, the problem of...
- With a Click of the Mouse. // Bio-IT World;Feb2003, Vol. 2 Issue 2, p46
Presents an overview of a study on mouse and human genome published in the December 2002 issue of the periodical "Nature." Differences between the genome of the mouse and that of man; Similarities in the gene level.
- New technology for an old favorite: lentiviral transgenesis and RNAi in rats. // Transgenic Research;Oct2007, Vol. 16 Issue 5, p571
AbstractÃ‚Â Ã‚Â The ability to produce targeted deletions in the mouse genome via homologous recombination has been a hallmark of mouse genetics, and has lead to the production of thousands of gene knockouts. New technologies are making it possible to disrupt gene function in many...