Controlled Clinical Trial of Combined Triiodothyronine and Thyroxine in the Treatment of Hypothyroidism

Smith, R. N.; Taylor, S. A.; Massey, J. C.
October 1970
British Medical Journal;10/18/1970, Vol. 4 Issue 4728, p145
Academic Journal
No abstract available.


Related Articles

  • Erratum to: Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for Graves' disease. Bunevicius, Robertas; Jakuboniene, Neli; Jurkevicius, Renaldas; Cernicat, Jurate; Lašas, Liudvikas; Prange, Arthur // Endocrine (1355008X);Feb2014, Vol. 45 Issue 1, p161 

    A correction to the article "Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for Graves' disease" that was published in the March 9, 2013 issue of the journal is presented.

  • Thyroxine treatment in patients with symptoms of hypothyroidism but thyroid function tests within the reference range: randomised double blind placebo controlled crossover trial. Pollock, M Anne; Sturrock, Alison; Marshall, Karen; Davidson, Kate M; Kelly, Christopher J G; McMahon, Alex D; McLaren, E Hamish // BMJ: British Medical Journal (International Edition);10/20/2001, Vol. 323 Issue 7318, p891 

    Objectives: To determine whether thyroxine treatment is effective in patients with symptoms of hypothyroidism but with thyroid function tests within the reference range, and to investigate the effect of thyroxine treatment on psychological and physical wellbeing in healthy participants. Design:...

  • Two thyroid hormones are better than one. Cerrato, Paul L. // RN;May99, Vol. 62 Issue 5, p104 

    Reports on the benefits of administering thyroxine in conjunction with triiodothyronine to treat hypothyroidism. Comparison with the effects of thyroxine when administered alone.

  • Treatment with T4 based on body weight improved hypothyroidism markers.  // Endocrine Today;1/10/2008, Vol. 6 Issue 1, p41 

    This article discusses research being done on the use of thyroxine in the management of central hypothyroidism. It references a study by M. Slawik et al., published in a 2007 issue of the "Journal of Clinical Endocrinology and Metabolism." Twenty-nine patients with hypopituitarism were enrolled...

  • Total and free thyroid hormone concentrations in patients receiving maintenance replacement treatment with thyroxine. Pearce, C.J.; Himsworth, R.L. // British Medical Journal (Clinical Research Edition);3/3/1984, Vol. 288 Issue 6418, p693 

    Examines the total and free serum hormone concentrations in hypothyroidism patients under thyroxine treatment. Correlation between trilodothyroxine concentration and free thyroxine concentrations; Assessment of the adequacy of replacement treatment; Combination of thyroxine treatment with in...

  • Effects of Thyroxine as Compared with Thyroxine plus Triiodothyronine in Patients with Hypothyroidism. Bunevicius, Robertas; Ka�anavicius, Gintautas; �alinkevicius, Rimas; Prange, Arthur J. // New England Journal of Medicine;02/11/99, Vol. 340 Issue 6, p424 

    Background: Patients with hypothyroidism are usually treated with thyroxine (levothyroxine) only, although both thyroxine and triiodothyronine are secreted by the normal thyroid gland. Whether thyroid secretion of triiodothyronine is physiologically important is unknown. Methods: We compared the...

  • Thyroid disease in pregnancy. Belchetz, P.E. // British Medical Journal (Clinical Research Edition);1/31/1987, Vol. 294 Issue 6567, p264 

    Examines the thyroid disease during pregnancy. Cause of hypothyroidism; Disassociation of maternal triiodothyronine concentration from fetal concentrations of thyroxine or triiodothyronine; Risk of fetal or neonatal thyroxicosis.

  • TSH Regulation Dynamics in Central and Extreme Primary Hypothyroidism. Marisa C. Eisenberg; Ferruccio Santini; Alessandro Marsili; Aldo Pinchera; Joseph J. DiStefano // Thyroid;Nov2010, Vol. 20 Issue 11, p1215 

    Background:Thyrotropin (TSH) changes in extreme primary hypothyroidism include increased secretion, slowed degradation, and diminished or absent TSH circadian rhythms. Diminished rhythms are also observed in central hypothyroid patients and have been speculated to be a cause of central...

  • Thyroid Hormone Replacement Therapy in Primary Hypothyroidism: A Randomized Trial Comparing L-Thyroxine plus Liothyronine with L-Thyroxine Alone. Escobar-Morreale, Héctor F.; Botella-Carretero, José I.; Gómez-Bueno, Manuel; Galán, José M.; Barrios, Vivencio; Sancho, José // Annals of Internal Medicine;3/15/2005, Vol. 142 Issue 6, p412 

    Background: Substituting part of the dose of L-thyroxine with small but supraphysiologic doses of liothyronine in hypothyroid patients has yielded conflicting results. Objective: To evaluate combinations of L-thyroxine plus liothyronine in hypothyroid patients that match the proportions present...

  • Thyroid Hormone Replacement – One Hormone or Two? Toft, Anthony D. // New England Journal of Medicine;02/11/99, Vol. 340 Issue 6, p469 

    The article presents the author's views on treatment for hypothyroidism with the thyroid extracts, synthetic triiodothyronine and synthetic thyroxine. Treatment with the latter led to high serum concentrations of triiodothyronine and heart palpitations in some patients. Information is given for...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics