TITLE

Alpha1 antitrypsin deficiency in chronic liver disease, and a report of cirrhosis and emphysema in adult members of a family

AUTHOR(S)
Kumar, P; Lancaster-Smith, M; Cook, P; Stansfeld, A; Clark, M L; Dawson, A M
PUB. DATE
March 1974
SOURCE
British Medical Journal;3/2/1974, Vol. 1 Issue 5904, p366
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
64109702

 

Related Articles

  • Alpha-1 Antirtypsin Deficiency, Emphysema, and Cirrhosis in an Adult. Cohen, Kenneth L.; Rubin, Peter E.; Echevarria, Rene A.; Sharp, Harvey L.; Teague, Perry O. // Annals of Internal Medicine;Feb73, Vol. 78 Issue 2, p227 

    Provides information on a study which described the association of a homozygous deficiency of serum alpha-1 antitrypsin with pulmonary emphysema in children. Details of a case report of a middle-aged man with pulmonary emphysema and homozygous alpha-1 antitrypsin deficiency; Characteristics of...

  • Emphysema, cirrhosis, and heart block in a young patient with partial a [sub1] antitrypsin deficiency (PiMZ phenotype). McDonald, Christine F.; Stewart, Paul M.; Blundell, Gillian; Crompton, Graham K. // British Medical Journal (Clinical Research Edition);12/14/1985, Vol. 291 Issue 6510, p1673 

    Presents a case report on the features of emphysema, cirrhosis and heart block in young patient with partial alpha[sub 1] antitrypsin deficiency (PiMZ phenotype) in Great Britain. Occurrence of PiMZ phenotype in British population; Association of PiMZ phenotype with alpha[sub 1] antitrypsin...

  • Alpha-1 antitrypsin deficiency. Primhak, R. A.; Tanner, M. S. // Archives of Disease in Childhood;Jul2001, Vol. 85 Issue 1, p2 

    α-1 antitrypsin is synthesized in the liver and protects lung alveolar tissues from destruction by neutrophil elastase. &alpha-1 antitrypsin deficiency is a common autosomal recessive condition in which liver disease results from retention of abnormal polymerised α-1 antitrypsin in the...

  • Liver Disease in Alpha 1-Antitrypsin Deficiency: A Review. Fairbanks, Kyrsten D.; Tavill, Anthony S. // American Journal of Gastroenterology;Aug2008, Vol. 103 Issue 8, p2136 

    Alpha 1-antitrypsin deficiency is an inherited metabolic disorder that predisposes the affected individual to chronic pulmonary disease, in addition to chronic liver disease, cirrhosis, and hepatocellular carcinoma. Just over one-third of genetically susceptible adult patients with the most...

  • Alpha-antitrypsin deficiency and liver disease.  // British Medical Journal (Clinical Research Edition);9/26/1981, Vol. 283 Issue 6295, p807 

    Examines the genetics of alpha-antitrypsin deficiency and liver disease in Sweden. Role of alpha-antitrypsin as a serum protease inhibitor; Identification on the autosomal codominant pattern of alleles; Association between alpha-antitrypsin and childhood cirrhosis.

  • Familial hypercholesterolaemai with alpha[1]-antitrypsin deficiency. Victorino, R.; Silveira, J.C.B.; Geada, H.; Moura, M.C. // British Medical Journal;2/18/78, Vol. 1 Issue 6110, p413 

    -Antitrypsin deficiency (PiZZ) has been recorded in association with pulmonary emphysema[1] and juvenile liver cirrhosis[2] but not with genetically determined conditions. We report a patient with familial hypercholesterolemia associated with obstructive lung disease with...

  • Cirrhosis Associated with Partial Deficiency of Alpha-1 Antitrypsin in an Adult. Campra, Jose L.; Craig, John R.; Peters, Robert L.; Reynolds, Telfer B. // Annals of Internal Medicine;Feb73, Vol. 78 Issue 2, p233 

    Presents a study which proposed that a partial deficiency may be related to liver disease in adults. Details of a report of a 63 year-old woman with partial deficiency of alpha-1 antitrypsin and liver cirrhosis of adult onset. Relationship between the deficiency and the liver disease in the...

  • Pathophysiology of hereditary emphysema. Stevens, Paul M.; Hnilica, Violette S.; Johnson, Philip C.; Bell, Robert L.; Stevens, P M; Hnilica, V S; Johnson, P C; Bell, R L // Annals of Internal Medicine;May71, Vol. 74 Issue 5, p672 

    Discusses a study which examined the relationship between alpha[sub 1]-antitrypsin deficiency and the development of emphysema. Materials and methodology; Clinical manifestations of chronic obstructive pulmonary disease; Findings of radioxenon studies on patients with alpha[sub 1]-antitrypsin...

  • DEFICITUL DE ALFA-1 ANTITRIPSINÄ‚ - REPERE PRACTICE PENTRU CLINICIAN. Ulmeanu, Ruxandra; Nebunoiu, Ana-Maria; Mihălţan, Florin Dumitru; Deleanu, Oana Claudia // Internal Medicine / Medicina Interna;2013, Vol. 10 Issue 5, p33 

    Alpha-1 antitrypsin deficiency is one of the most common identifiable genetic disease, mainly responsible for the occurrence of chronic obstructive pulmonary disease (COPD) and emphysema at young age, but also for liver abnormalities such as prolonged jaundice of the newborn or cirrhosis and...

  • Alpha-1 -Antitrypsin Deficiency: A Case of a Two-year Old Boy with Inherited Disease. Petlichkovski, Aleksandar; Peova, Sonja; Trajkov, Dejan; Arsov, Todor; Strezova, Ana; Hristomanova, Slavica; Djulejic, Eli; Petrov, Jordan; Spiroski, Mirko // Macedonian Journal of Medical Sciences;9/15/2008, Vol. 1 Issue 1, p59 

    Alpha-1-antitrypsin (AAT) is a protease inhibitor which plays an important role of protector of the lung tissues against the proteolytic effect of elastase secreted from neutrophils. Its deficiency is associated with liver disease in children and emphysema in adults. So far, more than 75...

Share

Read the Article

Other Topics