HIV-1, NFAT, and Cyclosporin: Immunosuppression for the Immunosuppressed?
- HIV nuclear import: What's the flap? Stevenson, Mario // Nature Medicine;Jun2000, Vol. 6 Issue 6, p626
Focuses on a triple stranded HIV cDNA intermediate of reverse transcription as a component of HIV nuclear import. Flow of genetic information from a retrovirus; Formation of reverse transcription complex; Models of flap-dependent HIV nuclear import.
- What is new in the nucleolus?: Workshop on the Nucleolus: New Perspectives. Matthews, David A.; Olson, Mark O. J. // EMBO Reports;Sep2006, Vol. 7 Issue 9, p870
The article reports on the "EMBO Workshop on the Nucleolus: New Perspectives," held at York, United Kingdom, from March 27-29, 2006. Information on the main focus of the workshop that revealed the involvement of nucleolus in internal functions of cells is presented. An overview of the structure,...
- Viral infection: Interfering with HIV infection. Hofer, Ursula // Nature Reviews Microbiology;Nov2013, Vol. 11 Issue 11, p742
The article reports on studies which identified an HIV restriction factor, the antiviral cytokine interferon (IFNa)-inducible myxovirus resistance 2 (MX2) protein. It refers to the identification of 14 IFN-induced genes that were upregulated in responsive HIV-resistant cells through...
- Decreased HIV Type 1 Transcription in CCR5-Î”32 Heterozygotes During Suppressive Antiretroviral Therapy. Wang, Charlene; Abdel-Mohsen, Mohamed; Strain, Matthew C.; Lada, Steven M.; Yukl, Steven; Cockerham, Leslie R.; Pilcher, Christopher D.; Hecht, Frederick M.; Sinclair, Elizabeth; Liegler, Teri; Richman, Douglas D.; Deeks, Steven G.; Pillai, Satish K. // Journal of Infectious Diseases;Dec2014, Vol. 210 Issue 11, p1838
Individuals who are heterozygous for the CCR5-Î”32 mutation provide a natural model to examine the effects of reduced CCR5 expression on human immunodeficiency virus (HIV) persistence. We evaluated the HIV reservoir in 18 CCR5-Î”32 heterozygotes and 54 CCR5 wild-type individuals during...
- Targeting a deadly scrap of genetic code. Cowley, Geoffrey; Hager, Mary // Bulletin with Newsweek;12/10/96, Vol. 116 Issue 6050, p68
Looks at the genetic aspects of the human immunodeficiency virus (HIV). How HIV invades the body's immune system; Potential treatments; Side-effects of present HIV treatments; A diagram visually depicting how HIV infects the immune system.
- Rare find. // Advocate;12/12/95, Issue 696, p11
Reports on the discovery of a rare strain of HIV that does not cause AIDS by a team of Australian researchers. Implications to research concerning vaccines and drugs for AIDS.
- Specific incorporation of cyclophilin A into HIV-1 virions. Franke, Ettaly Kara; Yuan, Hannah En Hui // Nature;11/24/1994, Vol. 372 Issue 6504, p359
Demonstrates the incorporation of cyclophilin A into HIV-1 virions but not in other primate immunodeficiency viruses. Requirements of cyclophilin A binding; Effect of Gag polyprotein on HIV replication.
- Functional association of cyclophilin A with HIV-1 virions. Thali, Markus; Bukivsky, Anatoly // Nature;11/24/1994, Vol. 372 Issue 6504, p363
Reports on the functional effect the formation of viral particles by p55 that contain cyclophilin A to HIV-1 virions. Effect of cyclospirin to cyclophilin A in vitro binding; Comparison of HIV-1 to other immunodeficiency viruses.
- An African HIV-1 sequence from 1959 and implications for the origin of the epidemic. Zhu, Tuofu; Korber, Bette T.; Nahmias, Andre J.; Hooper, Edward; Sharp, Paul M.; Ho, David D. // Nature;2/5/1998, Vol. 391 Issue 6667, p594
Reports the amplification and characterization of viral sequences from a 1959 African plasma sample that was previously found to be HIV-1 seropositive, thought to be the oldest known case of HIV-1 infection. What genetic analysis showed; Methods; The suggestion, if available, that HIV-1...