TITLE

Association of Prenatal and Postnatal Exposure to Lopinavir-Ritonavir and Adrenal Dysfunction Among Uninfected Infants of HIV-Infected Mothers

AUTHOR(S)
Simon, Albane; Warszawski, Josiane; Kariyawasam, Dulanjalee; Le Chenadec, Jerome; Benhammou, Valerie; Czernichow, Paul; Foissac, Frantz; Laborde, Kathleen; Tréluyer, Jean-Marc; Firtion, Ghislaine; Layouni, Inès; Munzer, Martine; Bavoux, Françoise; Polak, Michel; Blanche, Stéphane
PUB. DATE
July 2011
SOURCE
JAMA: Journal of the American Medical Association;7/6/2011, Vol. 306 Issue 1, p70
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article highlights the use of lopinavir-ritonavir among human immunodeficiency virus- (HIV) newborns not older than 14 days. In France, two newborns were reported to have transient elevation of 17-hydroxyprogesterone (17OHP), which prompted the release of warning for its use in premature newborns. The study conducted by the authors focused on comparing HIV-1-uninfected newborns postnatally treated with lopinavir-ritonavir and those treated with standard zidovudine. They concluded that postnatal treatment of liponavir-ritonavir were highly associated with transient adrenal dysfunction.
ACCESSION #
62965336

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics