TITLE

PATHOPHYSIOLOGY AND CLINICAL SPECTRUM OF FIBROMYALGIA A BRIEF OVERVIEW FOR MEDICAL COMMUNICATORS

AUTHOR(S)
Dhar, Madhurima
PUB. DATE
June 2011
SOURCE
AMWA Journal: American Medical Writers Association Journal;2011, Vol. 26 Issue 2, p50
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Fibromyalgia is a common, complex, rheumatic disorder of unknown etiology characterized by chronic widespread pain as well as other clinical features, such as consistent focal areas of tenderness (ie, tender points), stiffness, nonrestorative sleep, fatigue, frequent psychologic comorbidities (such as, depression and anxiety), and impaired memory and cognition. Fibromyalgia is a major cause of morbidity, poses a substantial economic burden on the health care system, and has a negative impact on patients' quality of life. Fibromyalgia is more common in women than in men and may also affect children. Although the pathophysiology underlying this condition is poorly understood, there is a complex interplay of dysfunctional central pain modulatory and neuroendocrine networks. Some studies have found a correlation between the onset and exacerbation of symptoms and periods of physical or emotional stress. Comorbidities that closely mimic the clinical spectrum of fibromyalgia and the overlap in symptomatology with other rheumatic conditions make diagnosis challenging. The overall management strategy for fibromyalgia involves a multidisciplinary pharmacologie, rehabilitative, and cognitive-behavioral approach. The aim of this article is to provide medical communicators with a brief overview of the epidemiology, pathophysiology, and clinical spectrum of this common multidimensional pain syndrome.
ACCESSION #
62851152

 

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