Dhar, Madhurima
June 2011
AMWA Journal: American Medical Writers Association Journal;2011, Vol. 26 Issue 2, p50
Academic Journal
Fibromyalgia is a common, complex, rheumatic disorder of unknown etiology characterized by chronic widespread pain as well as other clinical features, such as consistent focal areas of tenderness (ie, tender points), stiffness, nonrestorative sleep, fatigue, frequent psychologic comorbidities (such as, depression and anxiety), and impaired memory and cognition. Fibromyalgia is a major cause of morbidity, poses a substantial economic burden on the health care system, and has a negative impact on patients' quality of life. Fibromyalgia is more common in women than in men and may also affect children. Although the pathophysiology underlying this condition is poorly understood, there is a complex interplay of dysfunctional central pain modulatory and neuroendocrine networks. Some studies have found a correlation between the onset and exacerbation of symptoms and periods of physical or emotional stress. Comorbidities that closely mimic the clinical spectrum of fibromyalgia and the overlap in symptomatology with other rheumatic conditions make diagnosis challenging. The overall management strategy for fibromyalgia involves a multidisciplinary pharmacologie, rehabilitative, and cognitive-behavioral approach. The aim of this article is to provide medical communicators with a brief overview of the epidemiology, pathophysiology, and clinical spectrum of this common multidimensional pain syndrome.


Related Articles

  • Fibromyalgia: Improving Diagnostic and Treatment Strategies for Better Patient Outcomes. Goldenberg, Don L. // Journal of Managed Care Medicine;2012, Vol. 15 Issue 2, p14 

    The article focuses on Fibromyalgia (FM), a chronic pain disorder that requires accurate diagnosis and management. FM is an arbitrary label for a syndrome of chronic widespread pain but is the most common chronic widespread pain condition worldwide. FM can be difficult to diagnose because it is...

  • Fibromiyalji Sendromunda Uygulanan Tedavi Yontemleri. SİNDEL, Dilşad; SARAL, İlknur; ESMAEILZADEH, Sina // Turkish Journal of Physical Medicine & Rehabilitation / Turkiye ;Jun2012, Vol. 58 Issue 2, p136 

    Fibromyalgia syndrome (FMS) is a multisystem disorder, characterized by widespread pain that is usually associated with hyperalgesia and allodynia. Comorbidities such as fatigue, stiffness, insomnia, depression and anxiety make its classification and treatment difficult. The confluence of pain...

  • Adolescent Chronic Fatigue and Orthostatic Intolerance: Relationships Between Parental Attributes and Child Functioning. Kluck, Breann N.; Junghans-Rutelonis, Ashley N.; Jones, Amie E.; Fischer, Philip R.; Weiss, Karen E. // Clinical Pediatrics;Jan2017, Vol. 56 Issue 1, p85 

    The article discusses relationships between parental attributes and child functioning, citing its pertinence to chronic fatigue (CF) and orthostatic intolerance (OI) during adolescence. It states relation of CF and OI to postural orthostatic tachycardia syndrome (POTS), and mentions that OI and...

  • Improving the Recognition and Diagnosis of Fibromyalgia. Arnold, Lesley M.; Clauw, Daniel J.; McCarberg, Bill H. // Mayo Clinic Proceedings;May2011, Vol. 86 Issue 5, p457 

    Fibromyalgia (FM) is a chronic widespread pain disorder often seen In primary care practices. Advances in the understanding of FM pathophysiology and clinical presentation have improved the recognition and diagnosis of FM in clinical practice. Fibromyalgia is a clinical diagnosis based on signs...

  • Milnacipran: A serotonin and norepinephrine reuptake inhibitor for the management of fibromyalgia syndrome. Cios, Deborah A.; Kim, Julie E. // Formulary;Jul2009, Vol. 44 Issue 7, p197 

    Fibromyalgia syndrome (FMS) is a condition classified by widespread chronic pain and is associated with fatigue, morning stiffness, and disordered sleep. Milnaipran is a serotonin and norepinephrine reuptake inhibitor (SNRI) that was recently approved by FDA for the management of FMS. In...

  • Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case-control study. Ferini-Strambi, Luigi; Oertel, Wolfgang; Dauvilliers, Yves; Postuma, Ronald; Marelli, Sara; Iranzo, Alex; Arnulf, Isabelle; Birgit, Högl; Manni, Raffaele; Miyamoto, Tomoyuki; Fantini, Maria-Livia; Puligheddu, Monica; Jennum, Poul; Sonka, Karel; Santamaria, Joan; Zucconi, Marco; Rancoita, Paola; Leu-Semenescu, Smeranda; Frauscher, Birgit; Terzaghi, Michele // Journal of Neurology;Jun2014, Vol. 261 Issue 6, p1112 

    Patients with idiopathic REM sleep behavior disorder (iRBD) are at very high risk of developing neurodegenerative synucleinopathies, which are disorders with prominent autonomic dysfunction. Several studies have documented autonomic dysfunction in iRBD, but large-scale assessment of autonomic...

  • Fibromyalgia: evolving concepts over the past 2 decades. Fitzcharles, Mary-Ann; Ste-Marie, Peter A.; Pereira, John X. // CMAJ: Canadian Medical Association Journal;9/17/2013, Vol. 185 Issue 13, pE645 

    The article discusses developments related to the diagnosis and management of fibromyalgia. Symptoms of fibromyalgia include chronic widespread pain, fatigue, nonrestorative sleep and cognitive dysfunction. In diagnosing the condition, physicians are advised to perform a comprehensive clinical...

  • Timing of progesterone and allopregnanolone effects in a serial forced swim test. Contreras, Carlos M.; Francisco Rodríguez-Landa, Juan; Bernal-Morales, Blandina; Gutiérrez-García, Ana G.; Saavedra, Margarita // Salud Mental;jul2011, Vol. 34 Issue 4, p309 

    The forced swim test (FST) is commonly employed to test the potency of drugs to reduce immobility as an indicator of anti-despair. Certainly, antidepressant drugs reduce the total time of immobility and enlarge the latency to the first immobility period. FST is preceded by the open field test...

  • Parkinson's disease: top 10 causes of sudden deterioration. Magennis, Brian; Corry, Margarita // British Journal of Neuroscience Nursing;Oct/Nov2013, Vol. 9 Issue 5, p234 

    Sudden deterioration in Parkinson's disease is frequently encountered in clinical practice. It usually occurs over several days or weeks, and the cause is most likely related to a symptom rather than progression of the condition. It is important that the cause of the deterioration is treated and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics