Family origin and mortality: prospective Finnish cohort study

Saarela, Jan; Finnäs, Fjalar
January 2011
BMC Public Health;2011 Supplement 4, Vol. 11 Issue Suppl 4, p385
Academic Journal
Background: Death rates are notably higher in eastern Finland than in western Finland, and life expectancy of Finnish speakers shorter than that of Swedish speakers. The mortality differences correspond to recent genetic mappings of the population and are prominent for causes of death that are known to be associated with genetic risk factors. Methods: Using intergenerational data, we studied the impact of parental birth area on all-cause mortality risks of middle-aged men in Finland 1985-2003, assuming that geographic family origin reflects genetic predisposition to complex disorders. Relative death risks at ages 30-49 years were estimated by parental birth region and ethnicity, according to Cox regressions standardised for own education, family type at childhood, and year of birth. Results: The death risk of Finnish speakers born in eastern Finland was 1.13 (95% confidence interval 1.01 to 1.26) that of Finnish speakers born in western Finland, whereas that of Swedish speakers was only 0.60 (0.52 to 0.71). In Finnish speakers, the effects of own birth area and area of residence disappeared when parental birth area was accounted for. The death risk of persons with at least one parent born in eastern Finland was 1.23 (1.09 to 1.39) that of people with both parents born in western Finland. Conclusions: Parental birth area is the driving force behind the regional mortality difference in Finland. The findings highlight and give further support for the potentially important role of genetic risk factors in mortality. Close monitoring of persons' geographic and ethnic ancestry may promote public health and avoid many early deaths.


Related Articles

  • Trends in Respiratory System Cancer Mortality in Louisiana: Geographic Distributions in 1950-1969 and 1967-1976 Compared . Rothschild, Henry; Voors, Antonie W.; Weed, Sherrolyn; Vial, Lester J.; Welsh, Ronald A.; Johnson, William D. // American Journal of Public Health;Apr1979, Vol. 69 Issue 4, p380 

    The article discusses the study in the trends in respiratory system cancer (RSC) mortality in Louisiana. The State has became concern with epidemiology because mortality rates due to respiratory system cancers in white males were the highest. Data on deaths resulting from RSC during 1967 to 1976...

  • Multilevel modelling and public health policy. Leyland, Alastair H.; Groenewegen, Peter P. // Scandinavian Journal of Public Health;Sep2003, Vol. 31 Issue 4, p267 

    Background: Multilevel modelling is a statistical technique that extends ordinary regression analysis to the situation where the data are hierarchical. Such data form an increasingly common evidence base for public health policy, and as such it is important that policy makers should be aware of...

  • Comparison of severity of illness scoring systems in the prediction of hospital mortality in severe sepsis and septic shock. Crowe, Colleen A.; Kulstad, Erik B.; Mistry, Chintan D.; Kulstad, Christine E. // Journal of Emergencies, Trauma & Shock;Oct2010, Vol. 3 Issue 4, p342 

    Background: New scoring systems, including the Rapid Emergency Medicine Score (REMS), the Mortality in Emergency Department Sepsis (MEDS) score, and the confusion, urea nitrogen, respiratory rate, blood pressure, 65 years and older (CURB-65) score, have been developed for emergency department...

  • Non-leisure time physical activity is an independent predictor of longevity for a Taiwanese elderly population: an eight-year follow-up study. Yu-Pei Lin; Ying-Hsiang Huang; Feng-Hwa Lu; Jin-Shang Wu; Chih-Jen Chang; Yi-Ching Yang // BMC Public Health;2011 Supplement 4, Vol. 11 Issue Suppl 4, p428 

    Background: The aim of this study is to determine the relationship between leisure time physical activity (LTPA) and non-leisure time physical activity (NLTPA) on mortality among the elderly in Taiwan. Methods: This is a prospective observational cohort study. We analyzed the mortality data from...

  • Cancer risk among Japanese chromium platers, 1976-2003. Hara, Toshiyuki; Hoshuyama, Tsutomu; Takahashi, Ken; Delgermaa, Vanya; Sorahan, Tom // Scandinavian Journal of Work, Environment & Health;May2010, Vol. 36 Issue 3, p216 

    Objective The aim of our prospective cohort study was to assess cancer mortality risks among chromium platers. Methods The cohort comprised 1193 male platers (626 with exposure to chromium, the remainder with no exposure) with a follow-up period of 27 years (1 October 1976 to 31 December 2003)....

  • Thinking about Death Reduces Delay Discounting. Kelley, Nicholas J.; Schmeichel, Brandon J. // PLoS ONE;12/2/2015, Vol. 10 Issue 12, p1 

    The current study tested competing predictions regarding the effect of mortality salience on delay discounting. One prediction, based on evolutionary considerations, was that reminders of death increase the value of the present. Another prediction, based in part on construal level theory, was...

  • Consistency between education reported in health survey and recorded in death certificate. Young-Ho Khang; Hye Ryun Kim; Lynch, John W. // BMC Public Health;2007, Vol. 7 Issue 1, p294 

    Background: Education level is one indicator of socioeconomic position which, in several countries including South Korea, is provided though death certificate data. Its validity determines the usefulness of death certificate data for exploring the association between socioeconomic position and...

  • Indigenous Health and Socioeconomic Status in India. Subramanian, S. V.; Smith, George Davey; Subramanyam, Malavika // PLoS Medicine;Oct2006, Vol. 3 Issue 10, p1794 

    Background Systematic evidence on the patterns of health deprivation among indigenous peoples remains scant in developing countries. We investigate the inequalities in mortality and substance use between indigenous and non-indigenous, and within indigenous, groups in India, with an aim to...

  • MEASUREMENT AND COMPARISON OF AMERICAN COLLEGE STUDENTS' HISTORY INTERESTS. Dan, Yongjun; Lan, William // College Student Journal;Jun2010 Part B, Vol. 44 Issue 2, p424 

    The purpose of this article was to measure American non-history major students' history interests and compare their interest levels based on major, ethnicity, degree (undergraduate and graduate), age, and gender. We developed the history interest inventory for college students to measure their...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics