Testing the association between psychosocial job strain and adverse birth outcomes - design and methods

Larsen, Ann D.; Hannerz, Harald; Obel, Carsten; Thulstrup, Ane M.; Bonde, Jens P.; Hougaard, Karin S.
January 2011
BMC Public Health;2011, Vol. 11 Issue 1, p255
Academic Journal
Background: A number of studies have examined the effects of prenatal exposure to stress on birth outcomes but few have specifically focused on psychosocial job strain. In the present protocol, we aim to examine if work characterised by high demands and low control, during pregnancy, is associated with the risk of giving birth to a child born preterm or small for gestational age. Methods and design: We will use the Danish National Birth Cohort where 100.000 children are included at baseline. In the present study 49,340 pregnancies will be included. Multinomial logistic regression will be applied to estimate odds ratios for the outcomes: preterm; full term but small for gestational age; full term but large for gestational age, as a function of job-strain (high strain, active and passive versus low strain). In the analysis we control for maternal age, Body Mass Index, parity, exercise, smoking, alcohol use, coffee consumption, type of work (manual versus non-manual), maternal serious disease and parents' heights as well as gestational age at interview. Discussion: The prospective nature of the design and the high number of participants strengthen the study. The large statistical power allows for interpretable results regardless of whether or not the hypotheses are confirmed. This is, however, not a controlled study since all kinds of 'natural' interventions takes place throughout pregnancy (e.g. work absence, medical treatment and job-redesign). The analysis will be performed from a public health perspective. From this perspective, we are not primarily interested in the effect of job strain per se but if there is residual effect of job strain after naturally occurring preventive measures have been taken.


Related Articles

  • Work stress, smoking status, and smoking intensity: an observational study of 46 190 employees. Kouvonen, Anne; Kivimäki, Mika; Virtanen, Marianna; Pentti, Jaana; Vahtera, Jussi // Journal of Epidemiology & Community Health;Jan2005, Vol. 59 Issue 1, p63 

    Study objective: To examine the relation between work stress, as indicated by the lob strain model, and the effort-reward imbalance model, and smoking. Setting: Ten municipalities and 21 hospitals in Finland. Design and participants: Binary logistic regression models for the prevalence of...

  • Job Strain and Tobacco Smoking: An Individual-Participant Data Meta-Analysis of 166 130 Adults in 15 European Studies. Heikkila, Katriina; Nyberg, Solja T.; Fransson, Eleonor I.; Alfredsson, Lars; Bacquer, Dirk De; Bjorner, Jakob B.; Bonenfant, Sébastien; Borritz, Marianne; Burr, Hermann; Clays, Els; Casini, Annalisa; Dragano, Nico; Erbel, Raimund; Geuskens, Goedele A.; Goldberg, Marcel; Hooftman, Wendela E.; Houtman, Irene L.; Joensuu, Matti; Jöckel, Karl-Heinz; Kittel, France // PLoS ONE;Jul2012, Vol. 7 Issue 7, p1 

    Background: Tobacco smoking is a major contributor to the public health burden and healthcare costs worldwide, but the determinants of smoking behaviours are poorly understood. We conducted a large individual-participant meta-analysis to examine the extent to which work-related stress,...

  • Psychosocial job strain and risk of adverse birth outcomes: a study within the Danish national birth cohort. Larsen, Ann D.; Hannerz, Harald; Juhl, Mette; Obel, Carsten; Thulstrup, Ane Marie; Bonde, Jens Peter; Hougaard, Karin S. // Occupational & Environmental Medicine;Dec2013, Vol. 70 Issue 12, p845 

    Objective A number of studies examined the effects of prenatal stress on birth outcomes with diverging and inconclusive results. We aimed to examine if working with high job strain during pregnancy measured in week 16 was associated with risk of giving birth to a child born preterm or...

  • Interpregnancy Change in Smoking Habits and Risk of Preeclampsia: A Population-Based Study. Perni, Uma C.; Wikström, Anna-Karin; Cnattingius, Sven; Villamor, Eduardo // American Journal of Hypertension;Mar2012, Vol. 25 Issue 3, p372 

    BackgroundMaternal smoking has been associated with decreased risk of preeclampsia; however, it is uncertain whether this association is causal. An argument for causality would be strengthened if changes in smoking status across consecutive pregnancies were related to the risk of...

  • Characteristics and Factors Associated with the Risk of a Nicotine Exposed Pregnancy: Expanding the CHOICES Preconception Counseling Model to Tobacco. Parrish, Danielle; Sternberg, Kirk; Velasquez, Mary; Cochran, Jerry; Sampson, McClain; Mullen, Patricia // Maternal & Child Health Journal;Aug2012, Vol. 16 Issue 6, p1224 

    The preconception counseling model tested in the CDC funded Project CHOICES efficacy trial to reduce the risk of an alcohol-exposed pregnancy (AEP) could be extended to smokers to prevent a nicotine-exposed pregnancy (NEP), when pharmacotherapy can be provided safely and disclosure of these risk...

  • Pregnancy, maternal tobacco smoking, and early age leukemia in Brazil. Ferreira, Jeniffer Dantas; Couto, Arnaldo Cézar; Pombo-de-Oliveira, Maria S.; Koifman, Sergio // Frontiers in Oncology;Nov2012, Vol. 2, p1 

    Background: Cigarette smoking has been associated with acute myeloid leukemia (AML) but hypothesis on the association between maternal smoking during pregnancy and childhood leukemia remains unclear. Objectives:To investigate the association between maternal exposure to tobacco smoking during...

  • Relationship between occupational stress and burnout among Chinese teachers: a cross-sectional survey in Liaoning, China. Wang, Yang; Ramos, Aaron; Wu, Hui; Liu, Li; Yang, Xiaoshi; Wang, Jiana; Wang, Lie // International Archives of Occupational & Environmental Health;Jul2015, Vol. 88 Issue 5, p589 

    Objectives: Teaching has been reported to be one of the most stressful occupations in the world. Few studies have been conducted to explore the effects of occupational stress on burnout among teachers in developing countries. This study aimed to explore the relationship between occupational...

  • The Association of Alcohol Consumption with Outcome of Pregnancy. Marbury, Marian C.; Linn, Shai; Monson, Richard; Schoenbaum, Stephen; Stubblefield, Phillip G.; Ryan, Kenneth J. // American Journal of Public Health;Oct83, Vol. 73 Issue 10, p1165 

    Patterns of alcohol consumption were assessed in 12,440 pregnant women interviewed at the time of delivery. Only 92 women (0.7 per cent) reported drinking 14 or more drinks per week, with most consuming fewer than 21 drinks per week. In the crude data, alcohol intake of 14 or more drinks per...

  • Combined effect of smoking and occupational exposure to noise on hearing loss in steel factory workers. Mizoue, T.; Miyamoto, T.; Shimizu, T. // Occupational & Environmental Medicine;Jan2003, Vol. 60 Issue 1, p56 

    Analyzes the synergistic effect of smoking and occupational exposure to noise on hearing loss among steel factory workers. Reason for using logistic regression in the analysis; Definition of non-smokers; Calculation of hearing loss.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics