Mahmoudian, M.; Fallahati, M.; Faizi, M.; Bohlooli, S.; Sofian, N. D.
July 2011
International Journal of Pharmacy & Pharmaceutical Sciences;Jul2011, Vol. 3 Issue 3, p204
Academic Journal
Mebudipine and Dibudipine are two new calcium antagosists used in laboratory animals. Toxicological testing were evaluated in cultured mouse cells in-vitro and on growth yeast cells . It is shown that in these two system it is safe and no toxicological effect has been shown. Therefore, it is concluded that considering effect of mebudipne on yeast cells, heptocytes cells in-vitro, and reported effect on salmonella11, it can be said that is drug is safe and can be used in humans.


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