Frequency-shift vs phase-shift characterization of in-liquid quartz crystal microbalance applications

Montagut, Y. J.; García, J. V.; Jiménez, Y.; March, C.; Montoya, A.; Arnau, A.
June 2011
Review of Scientific Instruments;Jun2011, Vol. 82 Issue 6, p064702
Academic Journal
The improvement of sensitivity in quartz crystal microbalance (QCM) applications has been addressed in the last decades by increasing the sensor fundamental frequency, following the increment of the frequency/mass sensitivity with the square of frequency predicted by Sauerbrey. However, this sensitivity improvement has not been completely transferred in terms of resolution. The decrease of frequency stability due to the increase of the phase noise, particularly in oscillators, made impossible to reach the expected resolution. A new concept of sensor characterization at constant frequency has been recently proposed. The validation of the new concept is presented in this work. An immunosensor application for the detection of a low molecular weight contaminant, the insecticide carbaryl, has been chosen for the validation. An, in principle, improved version of a balanced-bridge oscillator is validated for its use in liquids, and applied for the frequency shift characterization of the QCM immunosensor application. The classical frequency shift characterization is compared with the new phase-shift characterization concept and system proposed.


Related Articles

  • Validation of a Phase-Mass Characterization Concept and Interface for Acoustic Biosensors. Montagut, Yeison; García, José V.; Jiménez, Yolanda; March, Carmen; Montoya, Ángel; Arnau, Antonio // Sensors (14248220);2011, Vol. 11 Issue 5, p4702 

    Acoustic wave resonator techniques are widely used in in-liquid biochemical applications. The main challenges remaining are the improvement of sensitivity and limit of detection, as well as multianalysis capabilities and reliability. The sensitivity improvement issue has been addressed by...

  • Oscillation-induced static deflection in scanning force microscopy. Heim, Lars-Oliver; Johannsmann, Diethelm // Review of Scientific Instruments;Jan2007, Vol. 78 Issue 1, p013902 

    Employing an atomic force microscope (AFM) in conjunction with a quartz crystal microbalance, we have investigated how a high-frequency lateral oscillation of the substrate influences the imaging process of the AFM. It was found that the time-averaged deflection of the cantilever (both vertical...

  • Noise Measurement Setup for Quartz Crystal Microbalance. Sedlak, Petr; Majzner, Jiri; Sikula, Josef; Hajek, Karel // Radioengineering;Apr2012, Vol. 21 Issue 1, p207 

    Quartz crystal microbalance (QCM) is a high sensitive chemical sensor which has found widespread spectrum of applications. There are several mechanisms that are related to fluctuation phenomena. Since the aim of our research is oriented to study the sensitivity and influence of different kind of...

  • Active control scheme for improving mass resolution of film bulk acoustic resonators. He, Xue-feng; Liu, Xing; Yin, Xian-fang; Wen, Zhi-yu; Chen, Ke-wan // Applied Mathematics & Mechanics;Jun2011, Vol. 32 Issue 6, p749 

    High mass resolution of sensors based on film bulk acoustic resonators (FBARs) is required for the detection of small molecules with the low concentration. An active control scheme is presented to improve the mass resolution of the FBAR sensors by adding a feedback voltage onto the driving...

  • Note: Sensitivity multiplication module for quartz crystal microbalance applications. Burda, Ioan; Silaghi, Andreea; Tunyagi, Arthur; Simon, Simion; Popescu, Octavian // Review of Scientific Instruments;2014, Vol. 85 Issue 2, p1 

    In this Note, a novel sensitivity multiplication module was added to classical quartz crystal microbalance (QCM). The purpose is to increase QCM frequency shift without changing nominal frequency of the quartz crystal resonator or nominal frequency value delivered to the frequency counter. Allan...

  • New frequency/voltage converters for ac-electrogravimetric measurements based on fast quartz crystal microbalance. Gabrielli, C.; Perrot, H.; Rose, D.; Rubin, A.; Toqué, J. P.; Pham, M. C.; Piro, B. // Review of Scientific Instruments;Jul2007, Vol. 78 Issue 7, p074103 

    A better understanding of the mechanisms located at the solid/electrolyte interface is becoming essential to the development of new applications in the electrochemical fields. The fast quartz crystal microbalance is an attractive and powerful gravimetric sensor which can be used in the dynamic...

  • Determination of flux ionization fraction using a quartz crystal microbalance and a gridded... Green, K.M.; Hayden, D.B.; Juliano, D.R; Ruiz, D.N. // Review of Scientific Instruments;Dec1997, Vol. 68 Issue 12, p4555 

    Reports on the determination of flux ionization fraction using a quartz crystal microbalance (QCM) and a gridded energy analyzer in an ionized magnetron sputtering system. Mounting of the sensor on a linear motion; Introduction of radio-frequency power through a coil; Determination of the metal...

  • Piezoelectric crystals enhance detection of biologicals. Cassidy, Robert // R&D Magazine;Jan95, Vol. 37 Issue 1, p50 

    Features piezoelectric (PZ) quartz crystal microbalance (QCM) systems useful for researchers as a fast, direct and cheaper method for real-time measurement of biomolecular reactions. Uses; Benefits; Developments in the field of PZ crystals. INSET: How PZ Biosensors work..

  • Erratum: Quartz crystal microbalance thin-film dissolution [Rev. Sci. Instrum. 60, 489 (1989)]. Hinsberg, William D.; Kanazawa, Kay K. // Review of Scientific Instruments;Dec1989, Vol. 60 Issue 12, p3835 

    Presents a correction to a research article on quartz crystal microbalance thin-film dissolution published in a 1989 issue of the journal 'Review of Scientific Instruments.'


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics