Comparative Efficiency and Safety of Pharmacological Approaches to the Management of Obesity

May 2011
Diabetes Care;May2011 Supplement 2, Vol. 34, pS349
Academic Journal
The article offers a comparison between the efficiency and safety of pharmacological approaches to obesity management. Several risks associated with excess weight include increased mortality, chronic morbidity and decreased quality of life. The mechanisms through which anti-obesity drug works are listed. One of which is suppression of food intake in the central nervous system (CNS). Sibutramine and orlistat are the only two drugs currently prescribed for treating obesity.


Related Articles

  • Obesity. Speakman, John R. // Biologist;Feb2003, Vol. 50 Issue 1, p11 

    Focuses on several aspects of obesity. Health risks of obesity; Information on the body mass index; Relationship between fatness and mortality; Trends in the prevalence of obesity.

  • Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in...  // American Journal of Clinical Nutrition;Oct98, Vol. 68 Issue 4, p899 

    Presents guidelines for the treatment of overweight and obesity in the United States. Details on the estimated number of overweight or obese adults in the US; Definition of overweight and obesity; Relation of higher body weights with the increase in all-cause mortality; In-depth look at the...

  • Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity. Joharapurkar, Amit A.; Dhanesha, Nirav A.; Jain, Mukul R. // Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy;2014, Vol. 7, p73 

    Worldwide prevalence of obesity has nearly doubled since 1980. Obesity is the result of interactions among the environmental factors, genetic predisposition, and human behavior. Even modest weight reduction in obese patients provides beneficial health outcomes. For effective weight reduction, a...

  • Part 2: Rationale for a Wellness Approach to Obesity. Ernsberger, Paul; Koletsky, Richard J. // Healthy Weight Journal;Mar/Apr2000, Vol. 14 Issue 2, p20 

    Part II. Focuses on the relationship between body weight and mortality. Correlation between smoking, body weight and mortality; Association of age with risks of obesity; Health benefits from obesity; Effectiveness of weight loss programs.

  • Letters. Morley, Nick; Brummitt, Charles F.; Willi, Sadie; White, Bill; Wolff, Heinz; Bebbington, Perry; Sinnott, Nigel; Budd, Leo; Sanderson, Neil; Crave, Ben; Champion, Paul; Millington, Peter; Darlington, Roger; Prentice, Rosie; Anthony, Simon; King, Brian; Thomkins, Peter; Szymczyk, Karen // New Scientist;5/29/2004, Vol. 182 Issue 2449, p30 

    Presents letters to the editor as published in the May 29, 2004 issue of the periodical "New Scientist." Discussion on whether chlorinated C [sub50] buckyballs be produced in large quantities to test their possible properties; Description of negative aspects of obesity; Infant mortality is much...

  • Body mass index and the risk of mortality in type II diabetic patients from Verona. Zoppini, G; Verlato, G; Leuzinger, C; Zamboni, C; Brun, E; Bonora, E; Muggeo, M // International Journal of Obesity & Related Metabolic Disorders;Feb2003, Vol. 27 Issue 2, p281 

    OBJECTIVE:: The relation between body weight and mortality in type II diabetic patients has not been fully elucidated. The aim of the present study was to evaluate the impact of body weight on mortality in a well-characterized type II diabetic cohort. RESEARCH DESIGN AND METHODS:: We examined a...

  • 2007 - The combination of low midarm muscle circumference and high waist circumference predicted higher mortality in older men. Peeters, Anna // ACP Journal Club;5/20/2008, Vol. 148 Issue 3, p10 

    The article presents information on a case study that was conducted to assess whether measures of adiposity and muscle mass are better tools to predict mortality in older men. About 4107 men in the age group of 60 to 79 were included in the study. During the course of the study, it was found...

  • T4:PL Management: Intervention studies in obesity. Torgerson, J.S. // International Journal of Obesity & Related Metabolic Disorders;May2003 Supplement, Vol. 27, pS19 

    International Journal of Obesity (2003) 27, S19. doi:10.1038/sj.ijo.0802341

  • Comparison of Body Mass Index and Waist Circumference as Predictors of All-Cause Mortality in a Male Insured Lives Population. Cumming, Marianne E.; Pinkham, C. Allen // Journal of Insurance Medicine;2008, Vol. 40 Issue 1, p26 

    Obesity assessed by body mass index (BMI) is associated with increased mortality risk, but there is uncertainty about whether BMI is the best way to measure obesity. Waist circumference (WC) has been proposed as a better measure. The Swiss Re BMI/WC Study was conducted to determine whether BMI...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics