Endothelial Factors and Diabetic Nephropathy

May 2011
Diabetes Care;May2011 Supplement 2, Vol. 34, pS291
Academic Journal
The article examines the link between endothelial dysfunction and diabetic nephropathy. Since 1996, the annual incidence rate of diabetes-related end-stage renal disease (ESRD) has been declining which suggested the condition as secondary to the documented pandemic of type 2 diabetes. A diagram is presented illustrating the principal mechanisms of diabetic glomerulopathy. Several pathways like the polyol and hexosamine pathway have been associated with the dysregulation of various vascular/endothelial growth factors.


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