TITLE

Endothelial Factors and Diabetic Nephropathy

AUTHOR(S)
KARALLIEDDE, JANAKA; GNUDI, LUIGI
PUB. DATE
May 2011
SOURCE
Diabetes Care;May2011 Supplement 2, Vol. 34, pS291
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article examines the link between endothelial dysfunction and diabetic nephropathy. Since 1996, the annual incidence rate of diabetes-related end-stage renal disease (ESRD) has been declining which suggested the condition as secondary to the documented pandemic of type 2 diabetes. A diagram is presented illustrating the principal mechanisms of diabetic glomerulopathy. Several pathways like the polyol and hexosamine pathway have been associated with the dysregulation of various vascular/endothelial growth factors.
ACCESSION #
61968027

 

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