Long-Acting Glucagon-Like Peptide 1 Receptor Agonists

May 2011
Diabetes Care;May2011 Supplement 2, Vol. 34, pS279
Academic Journal
The article examines the efficacy and tolerability of long-acting glucagon-like peptide 1 receptor agonists. The two classes of drugs for treating type 2 diabetes are glucagon-like peptide (GLP)-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors. A definition of incretin effect is presented, referring to the difference in insulin secretory response from an oral glucose load compared with intravenous glucose administration. Glucose-dependent insulinotropic polypeptide and GLP-1 are two incretin hormones used in glycemic control.


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