Incretin Effects on β-Cell Function, Replication, and Mass

May 2011
Diabetes Care;May2011 Supplement 2, Vol. 34, pS258
Academic Journal
The article examines the effects of incretin on the function, replication and mass of β-cell. Released from the gastrointestinal tract after a meal, incretin hormones enhance glucose-dependent insulin secretion from the pancreas and help in the overall regulation of glucose homeostasis. The two phases in which insulin secretion with meals occurs include the reduction of basal glucagon secretion and commencement for 10 minutes or after glucose exposure which is sustained until normoglycemia.


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