Profile of retinal vasculitis in a tertiary eye care center in Eastern India

Saurabh, Kumar; Das, Radha R.; Biswas, Jyotirmay; Kumar, Amitabh
July 2011
Indian Journal of Ophthalmology;Jul2011, Vol. 59 Issue 4, p297
Academic Journal
To provide a fact file on the etiology, clinical presentations and management of retinal vasculitis in Eastern India. Materials and Methods: Retrospective, record based analysis of retinal vasculitis cases in a tertiary care center in Eastern India from January 2007 to December 2009. Results: One hundred and thirteen eyes of 70 patients of retinal vasculitis were included in this study. Sixty (85.7%) patients were male (mean age 33+11.1 years) and 10 (14.3%) were female (mean age 32.4+13.6 years). Vasculitis was bilateral in 43 (61.4%) and unilateral in 27 (38.6%) patients. Commonest symptoms were dimness of vision (73; 64.6%) and floaters (36; 31.9%). Vascular sheathing (82; 72.6%) and vitritis (51; 45.1%) were commonest signs. Mantoux test was positive in 21 (30%) patients but tuberculosis was confirmed in only four (5.71%) patients. Raised serum angiotensin-converting enzyme level and positive antinuclear antibody level were reported in four (5.71%) patients each. Human leukocyte antigen B5 (HLA B5) marker was present in one (1.4%) patient. However, none of the total 70 patients were found to have a conclusively proven systemic disease attributable as the cause of retinal vasculitis. Oral corticosteroid (60; 85.7%) was the mainstay of treatment. Forty-eight (42.5%) eyes maintained their initial visual acuity and 43 (38%) gained one or more line at mean follow-up of 16.6+6.3 months. Conclusion: Retinal vasculitis cases had similar clinical presentations and common treatment plan. There was no systemic disease association with vasculitis warranting a careful approach in prescribing investigations.


Related Articles

  • Tuberculosis presenting as retinal vasculitis. Shah, S. M.; Howard, R. S.; Sarkies, N. J. C.; Graham, E. M. // Journal of the Royal Society of Medicine;Apr1988, Vol. 81 Issue 4, p232 

    The article presents medical cases involving tuberculosis presenting as retinal vasculitis in a 35-year-old Indian man. Previous studies have suggested a relationship between retinal vasculitis and tuberculosis, based on the occurrence of focal reactions in the retina after injection of...

  • Latente Tuberkulose. Bonomo, Carla; Brändli, Otto; Rampini, Silvana K. // Praxis (16618157);2/2/2011, Vol. 100 Issue 3, p125 

    No abstract available.

  • How should I interpret an interferon gamma release assay result for tuberculosis infection? Abubakar, Ibrahim; Stagg, Helen Ruth; Whitworth, Hilary; Lalvani, Ajit // Thorax;Mar2013, Vol. 68 Issue 3, p298 

    Background Interferon gamma release assays (IGRAs) are the first new diagnostic tests for latent tuberculosis (TB) infection (LTBI) since the century-old tuberculin skin test (TST). They are cell-mediated immune-based blood tests that have revolutionised LTBI diagnosis and are increasingly...

  • T-Cell Assays for Tuberculosis Infection: Deriving Cut-Offs for Conversions Using Reproducibility Data. Veerapathran, Anandharaman; Joshi, Rajnish; Goswami, Kalyan; Dogra, Sandeep; Moodie, Erica E. M.; Reddy, M. V. R.; Kalantri, Shriprakash; Schwartzman, Kevin; Behr, Marcel A.; Menzies, Dick; Pai, Madhukar // PLoS ONE;2008, Vol. 3 Issue 3, p1 

    Background: Although interferon-gamma release assays (IGRA) are promising alternatives to the tuberculin skin test, interpretation of repeated testing results is hampered by lack of evidence on optimal cut-offs for conversions and reversions. A logical start is to determine the within-person...

  • Tuberculosis in Neonates and Infants. Chrysanthi L. Skevaki; Dimitrios A. Kafetzis // Pediatric Drugs;2005, Vol. 7 Issue 4, p219 

    Tuberculosis is one of the leading infectious causes of death and as such represents a major global health problem. Infants may develop congenital tuberculosis from an infectious mother or, most commonly, they may acquire postnatal disease by contact with an infectious adult source. Important...

  • Abuse of over-the-counter drops sparks conjunctivitis. Scerra, Chet // Ophthalmology Times;06/01/97, Vol. 22 Issue 11, p25 

    Reports that nonprescription decongestant eyedrops have the potential to cause acute and chronic forms of conjunctivitis by pharmacologic, toxic and allergic mechanisms. Effects of abuse of eyedrops; Adverse systemic reactions to topical vasoconstrictor; Local effects of eyedrop abuse.

  • Tuberculosis, tenements and the epistemology of neglect: San Francisco in the nineteenth century. Craddock, S. // ECUMENE;Jan1998, Vol. 5 Issue 1, p53 

    A history of tuberculosis in the nineteenth-century American West is a difficult one to trace. Although the disease took a significant toll on urban populations in terms of death and disability, it was given relatively little attention by medical, public health and lay constituencies. First of...

  • Abdominal tuberculosis in Britain.  // British Medical Journal;6/18/1977, Vol. 1 Issue 6076, p1557 

    Examines the nature and etiology of abdominal tuberculosis in Great Britain. Signs and symptoms of the disease; Treatment of the disease; Complications of the disease.

  • Problems in the Serodiagnosis of Tuberculosis. Diena, B. B. // Annals of Internal Medicine;Jul71, Vol. 75 Issue 1, p132 

    Comments on a study regarding the problems in the serodiagnosis of tuberculosis (TB). Laboratory test for TB; Etiology of TB; Procedures of serodiagnosis.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics