TITLE

Assessment of anti-sperm antibodies in couples after testicular sperm extraction

AUTHOR(S)
Ozturk, Ufuk; Ozdemir, Erkan; Dede, Onur; Sagnak, Levent; Goksel Goktug, H. N.; Gurbuz, Oguz A.; Cagatay, Mustafa; Abdurrahim İmamoglu, M.
PUB. DATE
June 2011
SOURCE
Clinical & Investigative Medicine;Jun2011, Vol. 34 Issue 3, pE179
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: Testicular spermatozoa can be retrieved successfully by the testicular sperm extraction (TESE) procedure and used for intracytoplasmic sperm injection. Disruption in the blood-testis barrier can lead to the production of antisperm antibodies (ASA). The aim of this prospective study was to investigate the frequency of ASA formation in couples after TESE procedure. Methods: Thirty-seven couples were included in the study at the Urology Clinic of the Dr. Zekai Tahir Burak Women's Health Training and Research Hospital. History, physical examination, spermiogram, and endocrine profiles were obtained for all male patients. All the male patients in this study had been diagnosed with nonobstructive azoospermia (NOA) and underwent microdissection TESE. Secondary and tertiary cases were also included in the study. Serum samples were obtained from all 74 patients before TESE, and at three and 12 months after TESE. Serum ASA levels were determined. ANOVA was performed for statistical analysis for serum Follicle-Stimulating Hormone (FSH), testosterone and testicular volume. P < 0.05 was considered significant. Results: There were no differences in the testicular volumes, serum FSH and testosterone levels before and after TESE. None of the patients or their partners developed significant levels of ASA as a result of the TESE procedure. Conclusion: TESE procedure does not cause ASA production in either males or their female partners.
ACCESSION #
61263480

 

Related Articles

  • Double-blind prospective study comparing two automated sperm analyzers versus manual semen assessment. Lammers, J.; Splingart, C.; Barrière, P.; Jean, M.; Fréour, T. // Journal of Assisted Reproduction & Genetics;Jan2014, Vol. 31 Issue 1, p35 

    Purpose: Despite controversy regarding its clinical value, male fertility investigation mainly relies on semen analysis. Even though reference guidelines are available, manual sperm analysis still suffers from analytical variability, thus questioning the interest of automated sperm analysis...

  • Heterogeneous distribution of histone methylation in mature human sperm. Spina, Florenza; Romanato, Marina; Brugo-Olmedo, Santiago; Vincentiis, Sabrina; Julianelli, Vanina; Rivera, Rocio; Buffone, Mariano // Journal of Assisted Reproduction & Genetics;Jan2014, Vol. 31 Issue 1, p45 

    Purpose: To analyze the presence of various histone modifications in ejaculated human spermatozoa Methods: In this prospective study, seminal ejaculates from 39 normozoospermic individuals were evaluated for semen analysis and the presence of histone modifications in isolated nuclei. Results: We...

  • EFECTO DE LA ADICIÓN DE PLAS MA SEMINAL SOBRE LA ELIMINACIÓN DE GOTAS CITO PLÁSMICAS EN SEMEN DE SUS SCROFA LINNAEUS, 1758. Henao Uribe, Francisco Javier; Valencia Giraldo, Julián Alonso; Franco, Orlando Díaz; Rangel Sierra, Marcos Yesid // Boletín Científico Centro de Museos de Historia Natural;jul-dic2011, Vol. 15 Issue 2, p94 

    The cytoplasmic droplets (CDs) are remnants of the cytoplasm that are attached to the sperm after spermatogenesis. CDs constitute the most frequent sperm abnormality in pigs and are clearly related to low fertility. There are serious indications that fructose and the seminal plasma AMPc are...

  • Sperm Abnormalities in Post-thawed Semen of Tunisian Arab Stallions. Najjar, A.; Said, S. Ben; Benaoun, B.; Chetoui, C.; Ezzaouia, M.; Mrad, M. Ben // Pakistan Journal of Biological Sciences;2013, Vol. 16 Issue 19, p1069 

    The study was undertaken in order to evaluate sperm morphology features of post-thawed semen of Tunisian Arab stallions. Forty two ejaculates was collected and frozen, during years 2009 and 2010, from 9 stallions aged between 9 to 24 years. After thawing, sperm morphology was studied after...

  • Exploratory analysis of differences in sperm morphology in Nelore and Gir ( Bos indicus) bulls. Lucio, Aline; Ferraudo, Antonio; Oliveira, Leticia; Carmo, Adriana; Alves, Benner; Alves, Kele; Almeida, Solange; Deragon, Luis; Pereira, William; Carneiro, Luisa; Lima, Vera // Tropical Animal Health & Production;Jun2014, Vol. 46 Issue 5, p765 

    The aim of this study was to evaluate the effects of breed and season on semen quality parameters of zebu bulls. Data (1,632 registers) of semen production from Gir ( n = 4) and Nelore ( n = 15) bulls were collected between October 2005 and November 2009. The ejaculates were collected twice a...

  • Evaluating success of no-scalpel vasectomy by ligation and excision with fascial interposition in a large prospective study in Islamic Republic of Iran. Farrokh-Eslamlou, H.R.; Eslami, M.; Abdi-Rad, I.; Eilkhanizadeh, B. // Eastern Mediterranean Health Journal;Jun2011, Vol. 17 Issue 6, p517 

    The aims of this prospective, non-comparative study were to determine time to azoospermia and vasectomy success rate based on the results of semen analysis. A total of 334 men seeking vasectomy at a clinic in Urmia city, Islamic Republic of Iran were followed bi-weekly up to 24 weeks after...

  • Protective Effects of Antioxidants on Sperm Parameters and Seminiferous Tubules Epithelium in High Fat-fed Rats. Mortazavi, Motahareh; Salehi, Iraj; Alizadeh, Zohreh; Vahabian, Mehrangiz; Mohammadi Roushandeh, Amaneh // Journal of Reproduction & Infertility;Jan-Mar2014, Vol. 15 Issue 1, p22 

    Background: Prescription of antioxidants might increase the quality of sperm parameters and improve the rate of pregnancy in obese people who suffer from infertility. Therefore, the present study investigated protective effects of vitamin A, E and astaxanthin on sperm parameters and seminiferous...

  • Timing of removal of neck drains following head and neck surgery. Harris, Tashneem; Doolarkhan, Zubair; Fagan, Johannes J. // ENT: Ear, Nose & Throat Journal;Apr2011, Vol. 90 Issue 4, p186 

    Studies of the volume of drainage over a 24-hour period that is sufficient to allow for the removal of a neck drain after head and neck surgery have not been reported, and thus the timing of drain removal varies among surgeons and institutions. We conducted a prospective study of 47 patients who...

  • Y chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology. Bellver, J.; Meseguer, M.; Muriel, L.; García-Herrero, S.; Barreto, M. A. M.; Garda, A. L.; Remohí, J.; Pellicer, A.; Garrido, N.; García-Herrero, S; Remohí, J // Human Reproduction;Jul2010, Vol. 25 Issue 7, p1713 

    Background: The aim of the present study was to evaluate the implication of male factor, in terms of sperm DNA oxidation and fragmentation, and Y chromosome microdeletions in recurrent spontaneous abortion (RSA) of unknown origin in a strictly selected cohort.Methods: A...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics