TITLE

Vitamin D and hypertension in pregnancy

AUTHOR(S)
Ringrose, Jennifer S.; PausJenssen, Anne M.; Wilson, Merne; Blanco, Lara; Ward, Heather; Wilson, Thomas W.
PUB. DATE
June 2011
SOURCE
Clinical & Investigative Medicine;Jun2011, Vol. 34 Issue 3, pE147
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: Vitamin D Deficiency is common, particularly in northern latitudes. We examined the association between vitamin D status and hypertension in late pregnancy. Methods: A case-control study was conducted during two time periods: September-October, 2008, and January-March, 2009, in women near term. A case was defined as having two or more documented blood pressure readings above 140/90 (either/or) at any time during pregnancy (n=78). Controls had at least two blood pressure readings, with none above 140/90 during pregnancy (n=109). Serum 25-hydroxyvitamin D (25(OH)D) was measured in all participants. Results: In the summer, 13% of controls and 29% of the cases had 25(OH) D levels < 50 nmol/L. During the winter, these numbers rose to 44% and 49% respectively. Both cases and controls were more likely to be vitamin D deficient in the winter (p=0.002). There was a negative correlation between BMI and 25(OH)D (r=-0.202, p=0.002). In univariate analysis, cases had lower 25(OH)D (p=0.046), but also higher body mass index, so that in multivariate analysis 25(OH)D status was no longer significant. There was no difference in mean oral daily vitamin D intake (dietary intake and supplements, 746 and 785 IU respectively). Controls gained less weight in pregnancy. There was a negative correlation between the highest blood pressure measured in pregnancy and 25(OH)D levels (r= -0.118; p=0.012). Conclusion: There is a high prevalence of vitamin D deficiency in pregnant women recruited in Saskatoon, Saskatchewan. Women with low circulating vitamin D concentrations are more likely to have hypertension.
ACCESSION #
61263476

 

Related Articles

  • Relationship between preeclampsia and vitamin D deficiency: a case control study. Singla, Rimpi; Gurung, Padma; Aggarwal, Neelam; Dutta, Usha; Kochhar, Rakesh // Archives of Gynecology & Obstetrics;Jun2015, Vol. 291 Issue 6, p1247 

    Purpose: There is paucity of literature pertaining to association between vitamin D deficiency and preeclampsia from sunshine-rich countries like India. Further none of the studies have reported on relation with severity of preeclampsia. This study was carried out with a purpose of studying...

  • Serum 25-Hydroxyvitamin D Deficiency in Chinese Patients with Vitiligo: A Case-Control Study. Xin Xu; Wen-Wen Fu; Wen-Yu Wu // PLoS ONE;Dec2012, Vol. 7 Issue 12, p1 

    Background: Low vitamin D levels have been noted in patients with a variety of autoimmune diseases. A recent study showed that low vitamin D levels may be associated with vitiligo. Objectives: To assess 25-hydroxyvitamin D (25(OH)D) status in Chinese patients with vitiligo in comparison of...

  • Factores asociados con hipertensión gestacional y preeclampsia. Guzmán.-Juárez, Wendy; Ávila.-Esparza, Marina; Contreras.-Solís, Rosa Emma; Levario.-Carrillo, Margarita // Ginecologia y Obstetricia de Mexico;Jul2012, Vol. 80 Issue 7, p461 

    Background: Hypertensive complications in pregnancy are a cause of morbidity and mortality. Previous studies have identified similarities and differences in risk factors of hypertensive complications during pregnancy. Objective: Determine factors associated with gestational hypertension (HTG)...

  • PREGNANCY INDUCED HYPERTENSION; ASSESSMENT OF PROGNOSTIC VALUE OF PLATELET COUNT IN WOMEN WITH VARYING DEGREE. Khan, Asghar; Fahim, Amin; Qureshi, Aneela; Nizamani, Ghulam Shah; Azmi, Mohammad Ahmed // Professional Medical Journal;2014, Vol. 21 Issue 3, p436 

    Objective: To assess the early detection of thrombocytopenia in women presenting with varying degree of pregnancy induced hypertension (PIH). Study Design: A case control study. Place of Study: Hematology laboratory Isra University Hospital Hyderabad. Duration of Study: From July 2009 to...

  • The association between inherited thrombophilias and pregnancy-related hypertension recurrence. Mendilcioglu, Inanc; Bilgen, Turker; Arikan, Yunus; Keser, Ibrahim; Simsek, Mehmet; Timuragaoglu, Aysen // Archives of Gynecology & Obstetrics;Oct2011, Vol. 284 Issue 4, p837 

    Purpose: The aim of this study was to determine the association between inherited thrombophilias and pregnancy-related hypertension recurrence. Methods: In this case-control study, blood samples were obtained from patients who had at least two pregnancies complicated with pregnancy-related...

  • Estrogen synthesis genes CYP19A1, HSD3B1, and HSD3B2 in hypertensive disorders of pregnancy. Shimodaira, Masanori; Nakayama, Tomohiro; Sato, Ichiro; Sato, Naoyuki; Izawa, Noriko; Mizutani, Yoshihiro; Furuya, Kiyohide; Yamamoto, Tatsuo // Endocrine (1355008X);Dec2012, Vol. 42 Issue 3, p700 

    Hypertension in pregnancy is a multifactorial disorder caused by a complex combination of environmental factors and several predisposing genes. Since estrogen modulates placental vascular development, estrogen synthases are considered plausible candidate genes. The aim of this haplotype-based...

  • Clinical digest. Vitamin D deficiency can lead to adverse pregnancy outcomes in women.  // Nursing Standard;5/1/2013, Vol. 27 Issue 35, p15 

    The article discusses research which was reported in the article "Association Between Maternal Serum 25-Hydroxyvitamin D level and Pregnancy and Neonatal Outcomes: Systematic Review and Meta-Analysis of Observational Studies" by F. Aghajafari et al, was published in the "British Medical Journal"...

  • Exploring the concept of functional vitamin D deficiency in pregnancy: impact of the interaction between 25-hydroxyvitamin D and parathyroid hormone on perinatal outcomes. Hemmingway, Andrea; Kenny, Louise C; Malvisi, Lucio; Kiely, Mairead E // American Journal of Clinical Nutrition;Oct2018, Vol. 108 Issue 4, p821 

    Background: Associations of vitamin D with perinatal outcomes are inconsistent and few studies have considered the wider calcium metabolic system. Objectives: We aimed to explore functional vitamin D deficiency in pregnancy by investigating associations between vitamin D status, parathyroid...

  • Risk Factors for Toxoplasma gondii Infection in Pregnancy. Kapperud, Georg; Jenum, Pal A.; Stray-Pedersen, Babill; Melby, Kjetil K.; Eskild, Anne; Eng, Jan // American Journal of Epidemiology;1996, Vol. 144 Issue 4, p405 

    From 1992 to 1994, a prospective case-control study designed to identify preventable risk factors for Toxoplasma gondii infection in pregnancy was conducted in Norway. Case-patients were identified through a serologic screening program encompassing 37, 000 pregnant women and through sporadic...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics