TITLE

Evaluation of temperature-pulse centile charts in identifying serious bacterial illness: observational cohort study

AUTHOR(S)
Brent, Andrew J.; Lakhanpaul, Monica; Ninis, Nelly; Levin, Michael; MacFaul, Roddy; Thompson, Matthew
PUB. DATE
April 2011
SOURCE
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Apr2011, Vol. 96 Issue 4, p368
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background Distinguishing serious bacterial infection (SBI) from milder/self-limiting infections is often difficult. Interpretation of vital signs is confounded by the effect of temperature on pulse and respiratory rate. Temperature-pulse centile charts have been proposed to improve the predictive value of pulse rate in the clinical assessment of children with suspected SBI. Objectives To assess the utility of proposed temperature-pulse centile charts in the clinical assessment of children with suspected SBI. Study design and participants The predictive value for SBI of temperature-pulse centile categories, pulse centile categories and Advanced Paediatric Life Support (APLS) defined tachycardia were compared among 1360 children aged 3 months to 10 years presenting with suspected infection to a hospital emergency department (ED) in England; and among 325 children who presented to hospitals in the UK with meningococcal disease. Main outcome measure SBI. Results Among children presenting to the ED, 55 (4.0%) had SBI. Pulse centile category, but not temperature-pulse centile category, was strongly associated with risk of SBI (p=0.0005 and 0.288, respectively). APLS defined tachycardia was also strongly associated with SBI (OR 2.90 (95% CI 1.60 to 5.26), p=0.0002). Among children with meningococcal disease, higher pulse and temperature-pulse centile categories were both associated with more severe disease (p=0.004 and 0.041, respectively). Conclusions Increased pulse rate is an important predictor of SBI, supporting National Institute for Health and Clinical Excellence recommendations that pulse rate be routinely measured in the assessment of febrile children. Temperature-pulse centile charts performed more poorly than pulse alone in this study. Further studies are required to evaluate their utility in monitoring the clinical progress of sick children over time.
ACCESSION #
61211339

 

Related Articles

  • Identifying serious bacterial infection in children with fever.  // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;5/8/2010, Vol. 340 Issue 7754, p1013 

    The article discusses a study which investigated the identification of serious bacterial infection in children with fever by an emergency department doctor.

  • Risk score to stratify children with suspected serious bacterial infection: observational cohort study. Brent, Andrew J.; Lakhanpaul, Monica; Thompson, Matthew; Collier, Jacqueline; Ray, Samiran; Ninis, Nelly; Levin, Michael; MacFaul, Roddy // Archives of Disease in Childhood -- Fetal & Neonatal Edition;Apr2011, Vol. 96 Issue 4, p361 

    Objectives To derive and validate a clinical score to risk stratify children presenting with acute infection. Study design and participants Observational cohort study of children presenting with suspected infection to an emergency department in England. Detailed data were collected prospectively...

  • Safety netting in healthcare settings: what it means, and for whom? Roland, Damian; Jones, Caroline; Neill, Sarah; Thompson, Matthew; Lakhanpaul, Monica // Archives of Disease in Childhood -- Education & Practice Edition;Apr2014, Vol. 99 Issue 2, p48 

    Everyday thousands of children are presented to health care practitioners by concerned parents with the vast majority being simple self-limiting illness. However serious bacterial illness, chronic inflammatory conditions and mental health problems are repeatedly missed with significant...

  • Etiology and Clinical Manifestations of Fever in Infants Younger than 3 Months Old: A Single Institution Study, 2008-2010. Joon Young Seok; Ji Eun Kang; Eun Young Cho; Eun Hwa Choi; Hoan Jong Lee // Korean Journal of Pediatric Infectious Diseases;2012, Vol. 19 Issue 3, p121 

    Purpose: The purpose of this study is to investigate clinical features and causative organisms in febrile infants younger than three months, to help identification of high risk patients for serious bacterial infection (SBI). Methods: A total of 313 febrile infants younger than three months, who...

  • Emergency (clonal spread) of methicillin-resistant Staphylococcus aureus (MRSA), extended spectrum (ESBL) - and AmpC beta-lactamase-producing Gram-negative bacteria infections at Pediatric Department, Bosnia and Herzegovina. Uzunović, Selma; Bedenić, Branka; Budimir, Ana; Kamberović, Farah; Ibrahimagić, Amir; Delić-Bikić, Sabina; Sivec, Sara; Meštrović, Tomislav; Varda Brkić, Dijana; Rijnders, Michelle I. A.; Stobberingh, Ellen E. // Wiener Klinische Wochenschrift;Dec2014, Vol. 126 Issue 23/24, p747 

    Purpose: Aim of this study was to investigate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum (ESBL) and plasmid-mediated AmpC beta-lactamase producing Gram-negative bacteria in children. Methods: Antibiotic susceptibility of MRSA and beta-lactamase...

  • Evidence Guiding the Treatment of Children with Mycobacterial Diseases. Nicol, Mark P.; Wilkinson, Robert J. // Clinical Infectious Diseases;4/15/2007, Vol. 44 Issue 8, p1065 

    The article presents the author's views regarding the treatment of children with mycobacterial diseases. Mycobacterial diseases are widely prevalent in the world. However, the diagnosis and treatment of these diseases in children is a neglected research area. The choice of antibiotic therapy was...

  • Causes for hospitalization in Pediatric Ward in Prince Zaid Hospital. Salaita, Ghazi Al; Masri, Hazem Al; Amro, Khaled; Farah, Mahdi; Jaafreh, Majdi Al // Middle East Journal of Family Medicine;Oct2013, Vol. 11 Issue 8, p8 

    Objective: To identify the causes for hospitalization to the pediatric ward in Prince Zaid Hospital, and to analyze the types of illness and the outcome that resulted in hospital admission. Method: This is a one year retrospective study conducted in Prince Zaid hospital in south of Jordan. All...

  • Physical therapy improves positional preference-related skull deformation.  // Contemporary Pediatrics;Oct2008, Vol. 25 Issue 10, p96 

    The article discusses research being done on the effectiveness of physical therapy in reducing the prevalence of severe skull deformation in children with side preferences. It references a study by L. A. van Vlimmeren et al published in a 2008 issue of "Archives of Pediatrics & Adolescent...

  • Specificity and Sensitivity of Hemosiderin-Laden Macrophages in Routine Bronchoalveolar Lavage in Children. Salih, Zeynep N.; Akhter, Afreen; Akhter, Javeed // Archives of Pathology & Laboratory Medicine;Nov2006, Vol. 130 Issue 11, p1684 

    Context.—The presence of iron or hemosiderin in macrophages obtained in routine bronchoalveolar lavage is considered crucial in the diagnosis of the clinical syndrome of hemosiderosis. However, there do not appear to be any data on the sensitivity and specificity of the finding of...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics