TITLE

Trans-apical and trans-axillary percutaneous aortic valve implantation as alternatives to the femoral route: short- and middle-term results

AUTHOR(S)
Taramasso, Maurizio; Maisano, Francesco; Cioni, Micaela; Denti, Paolo; Godino, Cosmo; Montorfano, Matteo; Colombo, Antonio; Alfieri, Ottavio
PUB. DATE
July 2011
SOURCE
European Journal of Cardio-Thoracic Surgery;Jul2011, Vol. 40 Issue 1, p49
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Abstract: Objective: Trans-catheter aortic valve implantation (TAVI) is an alternative for patients not eligible for surgical aortic valve replacement. When peripheral access is not amenable by the transfemoral route (TF-TAVI), the most-used approaches are the trans-apical (TAp-TAVI) and the trans-axillary (TAx-TAVI). The aim of this study is to report the outcomes in a single-center series of consecutive patients treated by TAVI using the different approaches. Methods: From November 2007 to June 2010, 177 patients underwent TAVI by the same multispeciality valve team. TAp-TAVI was performed in the operative room, while TF-TAVI and TAx-TAVI were done in the catheterization laboratory. Follow-up was 100% complete (mean 6.0±6.8 months). Results: TF-TAVI, TAx-TAVI, and TAp-TAVI were performed in 140 (79.1%), 19 (10.7%), and 16 patients (9.1%), respectively. The groups were not different in terms of age (p =0.6), left ventricular ejection fraction (LVEF) (p =0.6), Log-EuroSCORE (European System for Cardiac Operative Risk Evaluation) (p =0.3), and Society of Thoracic Surgeons (STS) score (p =0.7), while peripheral artery disease was higher in the TAp-TAVI and TAx-TAVI groups compared with the TF-TAVI group (p <0.0001). The Charlson score was 10.7±14.9, 5.8±1.2, and 5.9±1.8 for TAp-TAVI, TAx-TAVI, and TF-TAVI, respectively (p =0.02). In-hospital (30-day) mortality was 1.4% (2/140), 12.5% (2/16), and 5.3% (1/19) for TF, Tap, and TAx, respectively (p =0.03). At follow-up, 6 months’ actuarial survival was 72.2±12.0%, 67.4±17.4%, and 88.4±3.1% for TAp-TAVI, TAx-TAVI, and TF-TAVI, respectively (p =0.3). Conclusions: Similar to findings from recent, larger trials, patients undergoing TF-TAVI in high-risk patients had excellent 6-month results. Although TAx-TAVI was associated with lower hospital mortality, it shared the same 6-month outcomes of TAp-TAVI, probably due to a similar selection bias.
ACCESSION #
61175270

 

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