Pulmonary sequestration: a retrospective analysis of 2625 cases in China

Wei, Yong; Li, Fan
July 2011
European Journal of Cardio-Thoracic Surgery;Jul2011, Vol. 40 Issue 1, pe39
Academic Journal
Abstract: Objective: Pulmonary sequestration is a congenital lung malformation, which is often misdiagnosed as lung cancer, pulmonary cysts, mediastinal tumors, etc. Therefore, more research on the clinical characteristics of pulmonary sequestration should be carried out to improve the preoperative diagnosis rate. Methods: The study used was a retrospective analysis of 2625 cases of pulmonary sequestration well documented in the Chinese National Knowledge Infrastructure from 1998 to 2008. Analysis was performed on the patients’ age, gender, symptom, chest computed tomography (CT) scan, chest radiograph, lesion localization, arterial supply, venous drainage, and incorrect preoperative diagnosis. Results: A total of 2625 cases of pulmonary sequestration was reported in the Chinese National Knowledge Infrastructure from 1998 to 2008, and the male:female ratio was 1.58:1. The symptoms of pulmonary sequestration were cough, sputum, fever, hemoptysis, and chest pain, with 13.36% of patients being asymptomatic. Chest CT scan showed mass lesions (49.01%), cystic lesions (28.57%), cavitary lesions (11.57%), and pneumonic lesions (7.96%). The sequestration was mainly located in the lower lobe, primarily in the left posterior basal segment (66.43%) and in the right posterior basal segment (20.16%). Pulmonary sequestrations were divided into two types, intralobar sequestration (83.95%) and extralobar sequestration (16.05%). Bilateral sequestrations were rare – only three cases had been reported. The arterial supply was mainly provided by branches of thoracic aorta (76.55%) and abdominal aorta (18.47%). The mean incorrect preoperative diagnosis rate was as high as 58.63%. A comparison between pediatric and adult patients indicated that the subtype ratio (intralobar/extralobar) was higher in the adult group than that in the pediatric group (P <0.001). Conclusions: Clinical manifestations of pulmonary sequestration varied and preoperative diagnosis was often incorrect. To improve the preoperative diagnosis rate, we should take full advantage of symptoms, image performance, and localization characteristics. A certain early-onset age, recurrent pneumonias, mass or cyst lesion located in the lower lobe, and aberrant arterial supply are indicators for the diagnosis.


Related Articles

  • Congenital Heterotopic Gastrointestinal Cyst of the Oral Cavity: Case Report and Review of the Literature. Safar, Ali; Carpenter, Blair; Vaccani, Jean-Philippe // Journal of Otolaryngology -- Head & Neck Surgery;Jun2008, Vol. 37 Issue 3, pE100 

    The article presents a case study of a three month old boy who presented to physicians with soft tongue swelling. A discussion of diagnostic testing which was conducted on the boy and resulted in him receiving a diagnosis of congenital heterotopic gastrointestinal cyst of the oral cavity is...

  • OUTCOMES OF CONGENITAL CYSTIC LUNG MALFORMATIONS IN CHILDREN AND THEIR MANAGEMENT ACCORDING TO CLINICAL PROGRESSION. Galyagina, N. A.; Khaletskaya, O. V. // Medical Technologies in Medicine / Sovremennye Tehnologii v Medi;2014, Vol. 6 Issue 2, p77 

    The aim of the investigation was to analyze the outcomes of congenital cystic lung malformations in children in accordance with clinical manifestations in pre- and postnatal period, and justify the management of patients. Materials and Methods. We analyzed retrospectively 45 cases of congenital...

  • Congenital lung lesions: classification and concordance of radiological appearance and surgical pathology. Farrugia, M. K.; Raza, S. A.; Gould, S.; Lakhoo, K. // Pediatric Surgery International;Sep2008, Vol. 24 Issue 9, p987 

    Congenital lung lesions are diagnosed antenatally in the majority of cases. Postnatal management includes chest radiography and CT-scanning, followed by either surgical resection or CT surveillance. Pre-operatively, lesions are often "labelled" as CCAM (and the Stocker classification incorrectly...

  • Epidermoid cyst in intrapancreatic accessory spleen: computed tomography findings and clinical manifestation. Hu, Shudong; zhu, Linxiao; song, Qi; Chen, Kemin // Abdominal Imaging;Oct2012, Vol. 37 Issue 5, p828 

    Objective: This study aims to assess retrospectively the imaging features of computed tomography (CT) and clinical characteristics of epidermoid cyst in intrapancreatic accessory spleen (ECIPAS). Methods: Seven consecutive patients with pathologically confirmed ECIPAS were included. CT images...

  • Linfangioma abdominal. Caso clínico. TORREALBA A., IGNACIA; DE BARBIERI M., FLORENCIA // Revista Chilena de Pediatría;ene/Feb2012, Vol. 83 Issue 1, p68 

    Abdominal lymphangioma is a rare benign congenital malformation of the mesenteric and/or retroperitoneal lymphatics, more frequent in pediatrics. Objective: To report a case with unusual clinical presentation oflymphangioma. Clinical Case: A two-year old boy previously health who presented with...

  • Thyroglossal Duct Cyst-More Than Just an Embryological Remnant. Narayana Moorthy, Sujatha; Arcot, Rekha // Indian Journal of Surgery;Jan2011, Vol. 73 Issue 1, p28 

    Thyroglossal duct cyst is a congenital malformation that occurs due to incomplete closure of the thyroglossal duct. Apart from being a quiescent embryological remnant, it presents itself clinically at any age and often requires surgical excision. Twenty four patients were encountered at Sri...

  • Pathologic Review of Cystic and Cavitary Lung Diseases. Na Rae Kim; Joungho Han // Korean Journal of Pathology;Oct2012, Vol. 46 Issue 5, p407 

    Pulmonary cystic and cavitary lesions caused by diverse etiologies are commonly encountered in chest imaging. The terms "cyst"and "cavity"are used to describe air-filled regions in the center of a nodule or consolidation of the lung. To date, only radiologic aspects of these lesions have been...

  • Congenital Orbital Cysts Arising from the Common Sheath of Levator Palpebra and Superior Rectus Muscles. Kiratli, Hayyam; Tarlan, Berçin; Söylemezoğlu, Fiğen // Pediatric & Developmental Pathology;Mar/Apr2012, Vol. 15 Issue 2, p170 

    The article presents separate case studies of two patients who suffer from congenital cysts which result in the development of the upper eyelids' blepharoptosis in early adulthood. In the first case, a cystic lesion between rectus and palpebra muscles has been found in the left upper eyelid of a...

  • Fibropolycystic liver disease in children. Veigel, Myka Call; Prescott-Focht, Julia; Rodriguez, Michae G.l; Zinati, Reza; Lei Shao; Moore, Charlotte A. W.; Lowe, Lisa H. // Pediatric Radiology;Apr2009, Vol. 39 Issue 4, p317 

    Fibropolycystic liver diseases are a group of associated congenital disorders that present most often in childhood. These disorders include congenital hepatic fibrosis, biliary hamartomas, autosomal dominant polycystic liver disease, choledochal cysts and Caroli disease. We present a discussion...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics