The influence of gender on mortality in patients after thoracic endovascular aortic repair

Czerny, Martin; Hoebartner, Michael; Sodeck, Gottfried; Funovics, Martin; Juraszek, Andrzej; Dziodzio, Tomasz; Grimm, Michael; Ehrlich, Marek
July 2011
European Journal of Cardio-Thoracic Surgery;Jul2011, Vol. 40 Issue 1, pe1
Academic Journal
Abstract: Objectives: The aim of this study was to determine if gender affects mortality in patients after thoracic endovascular aortic repair (TEVAR). Methods: We retrospectively analyzed 286 consecutive patients undergoing TEVAR at our institution during a 12-year period (female 29%, median age 69 years). Chronic health conditions, risk factors, as well as early and long-term outcome were assessed. Follow-up data were available in all patients. Results: For female gender, 1-year survival and 5-year survival was 84% and 56% versus 83% and 60% for male gender. No significant gender influence was observed (odds ratio (OR) 0.96, 95% confidence interval (CI) 0.59–1.56). Furthermore, no significant gender influence could be observed according to the individual indication – atherosclerotic aneurysms (OR 0.78 95%CI 0.41–1.47), acute type B dissections (OR 0.78 95%CI 0.21–2.83), penetrating atherosclerotic ulcers/intramural hematoma (OR 1.48 95%CI 0.53–4.19), and traumatic aortic lesions (OR 1.48 95%CI 0.53–4.19). Age (OR 3.6 95%CI 1.24–10.45) and chronic obstructive pulmonary disease (COPD; OR 3.09 95%CI 0.98–9.73) were independent predictors of mortality in females. Conclusions: Gender does not affect mortality in patients after TEVAR irrespective of the underlying indication, atherosclerotic aneurysms, acute type B dissections, penetrating ulcers/intramural hematoma, and traumatic aortic lesions. Classical risk factors such as age and the presence of COPD at the time of TEVAR remain the most important risk factors in females.


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