TITLE

The analgesic and antiemetic efficacy of gabapentin or ergotamine/caffeine for the treatment of postdural puncture headache

AUTHOR(S)
Erol, D. D.
PUB. DATE
June 2011
SOURCE
Advances in Medical Sciences (De Gruyter Open);2011, Vol. 56 Issue 1, p25
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: We investigated the analgesic and antiemetic efficacy of gabapentin or ergotamine/caffeine (Cafergot), in addition to conservative treatment consisting of bed rest and adequate fluid intake, for the treatment of postdural puncture headache (PDPH).Methods: In this randomized, prospective, controlled study, gabapentin or Cafergot was administered to 42 adult patients suffering from PDPH. Patients were asked to record the severity of their headache and the number of vomiting episodes on a visual analogue scale (VAS) on days 1, 2, 3 and 4. The pain scale consisted of a 10 cm horizontal line marked from 0 (denoting no pain) to 10 (denoting worst possible imaginable pain) Emesis was scored as 0 = no emetic symptoms, 1 = nausea or 2 = vomiting.Results: Demographic and anesthetic variables were similar between the groups. Gabapentin group had less pain, nausea and vomiting compared to the Cafergot group. No patients withdrew, gabapentin and Cafergot were well tolerated, and adverse events (somnolence, dizziness, tremor, and ataxia) did not occur.Conclusions: Gabapentin significantly reduced pain, nausea and vomiting compared to Cafergot in patients with PDPH. Lastly, we hypothesize that the gabaergic action of gabapentin, perhaps combined with other mechanisms, such as calcium channel blockade, may be responsible for its remarkable effects on PDPH.
ACCESSION #
61031862

 

Related Articles

  • Growing pains. BRAY, KARINA // Choice;Sep2010, p26 

    The article discusses the use of painkillers to treat headache. Primary headaches and secondary headaches are the two categories of headaches. Over-the-counter (CTC) pain relievers such paracetamol and aspirin can temporarily treat most tension-type headaches. While mild migraines can be treated...

  • Zolmitriptan is effective in relieving post-dural puncture headache in young parturients. Riaz, Azmat; Khan, Rao Ali Shan; Sharif, Asjad // Anaesthesia, Pain & Intensive Care;Apr-Jun2014, Vol. 18 Issue 2, p147 

    Objective: This comparative study was designed to assess the efficacy of zolmitriptan, a triptan widely employed as first-line therapy for migraine, in relieving post-dural puncture headache in parturients who were operated for cesarian section under spinal anesthesia. Methodology: The study was...

  • Post Dural Puncture Headache - A case report. Karkada, Eva Chris // International Journal of Nursing Education;Jul-Dec2011, Vol. 3 Issue 2, p29 

    Postpartum women are at risk for developing a headache after they undergo caesarean section with spinal anaesthesia. These headaches are likely due to leakage of cerebrospinal fluid at the puncture site. While usually mild and self-limited, some headaches may be persistent and severe, adding to...

  • Non invasive Management of Post Dural Puncture Headache -A Comparison. Sen, J.; Sen, B. // Bangladesh Journal of Medical Science;Apr2014, Vol. 13 Issue 2, p114 

    Aim: To evaluate the efficacy of oral Theophylline for the management of post dural puncture headache (PDPH). Material and Method: Forty patients with PDPH, whose surgeries were done under spinal anaesthesia, were selected randomly and divided into two groups of 20 each. One group to receive...

  • POSTDURAL PUNCTURE HEADACHE; COMPARISON BETWEEN LUMBAR PUNCTURE NEEDLE NO 25 G AND 27 G. Sohail, Behzad; Sharif, Asjad; Adnan, Ahmed; Iqbal, Rashid; Zahoor, Umer // Professional Medical Journal;Jan2011, Vol. 18 Issue 1, p51 

    Objective: To evaluate the role of needle diameter in causing postdural puncture headache (PDPH) in patients undergoing elective caesarian section. Study Design: Comparative cross-sectional study. Place and Duration of Study: This study was conducted in Department of Anaesthesia and Intensive...

  • Comparing the effect of pregabalin, gabapentin, and acetaminophen on post-dural puncture headache. Mahoori, Alireza; Noroozinia, Heydar; Hasani, Ebrahim; Saghaleini, Hadi // Saudi Journal of Anaesthesia;Jul-Sep2014, Vol. 8 Issue 3, p374 

    Introduction: Post-dural puncture headache (PDPH) is a common complication of lumbar puncture for any purpose. To avoid the need for invasive methods of treating PDPH such as blood patch, the search for novel pharmacological agents to manage PDPH continues. The aim of this study was to compare...

  • Painkillers may make headaches worse.  // USA Today Magazine;Oct93, Vol. 122 Issue 2581, p6 

    Reports on evidence suggesting that people with chronic headaches are doing themselves more harm than good by taking too many prescription or over-the-counter painkillers. Effects of overuse of painkillers; Contribution of regular use of analgesics to the transformation of an occasional...

  • Do you really need that aspirin? Day, Michael // New Scientist;6/08/96, Vol. 150 Issue 2033, p10 

    Reports on the aggravating effects of painkillers such as aspirin and paracetamol. Opinion of the European Headache Federation; Call on the European Union and national governments to commission research to discover the extent of the problem; Worsening of headaches with the use of painkillers.

  • Diagnose your headache. Geraci, Ron // Men's Health;Dec97, Vol. 12 Issue 10, p38 

    Presents ways for diagnosing headache. Kinds of headache and its symptoms; Medicine for various kinds of headaches.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics