TITLE

Langerhans cell/indeterminate cell histiocytoma

AUTHOR(S)
Bonifazi, E.; Milano, A.
PUB. DATE
October 2010
SOURCE
European Journal of Pediatric Dermatology;Oct2010, Vol. 20 Issue 4, p262
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We present a case of Langerhans cell histiocytoma and review the relevant literature. A diagnosis of this type should be suspected when facing a congenital nodule, 1-2 cm in size, especially when there is involvement of the epidermis with blisters, erosions or crusts. In case of such a suspicion it is sufficient to perform a biopsy or excision to confirm the diagnosis. Once diagnosed, given the spontaneous regression and the lack of on site or remote recurrences in all the cases reported, you do not need radical surgery and clinical monitoring is sufficient without making any examination potentially harmful to the baby.
ACCESSION #
61029763

 

Related Articles

  • Functional Human Epidermal Langerhans Cells that Lack Birbeck Granules. Mommaas, Mieke; Mulder, Aat; Vermeer, Bert Jan; Koning, Frits // Journal of Investigative Dermatology;Dec94, Vol. 103 Issue 6, p807 

    Birbeck granules (BG) are cytoplasmic organelles that are only found in Langerhans cells (LC). The function of BG is still unclear, although it has been claimed that they are actively involved in receptor-mediated endocytosis and participate in the antigen-processing/presenting function of LC....

  • HIV-Infected Langerhans Cells Constitute a Significant Proportion of the Epidermal Langerhans Cell Population Throughout the Course of HIV Disease. Compton, Carolyn C.; Kupper, Thomas S.; Nadire, Kathleen B. // Journal of Investigative Dermatology;Dec96, Vol. 107 Issue 6, p822 

    Human immunodeficiency virus (HIV) is known to infect Langerhans cells, but controversy still exists about the occurrence of HIV-infected Langerhans cells in the skin of HIV-infected individuals and about the density of epidermal Langerhans cells during the course of HIV disease. In this study,...

  • Effect of Chronologic Aging and Ultraviolet Irradiation on Langerhans Cells in Human Epidermis. Gilchrest, Barbara A.; Murphy, George F.; Soter, Nicholas A. // Journal of Investigative Dermatology;Aug82, Vol. 79 Issue 2, p85 

    The effect of aging on epidermal Langerhans cells (LC) and on their response to a single ultraviolet (UV) exposure was studied in skin biopsy specimens of healthy adults, 4 aged 22-26 yr and 7 aged 62-86 yr. In unirradiated skin, old adults had fewer LC than young adults, 5.8 ± 1.1 versus...

  • Reduced Epidermal Langerhans Cell Densities in Patients with Pulmonary Malignancies Do Not Correlate with Anergy or Nutritional Status. Fox, J. L.; Berman, B.; Goodman, R. // Journal of Dermatologic Surgery & Oncology;Nov85, Vol. 11 Issue 11, p1087 

    Epidermal Langerhans cell (ELC) densities are markedly reduced in a number of clinical situations including anergic sarcoidosis patients. To help determine whether this reduction is related to the anergic or nutritional status of the patient, we examined the non-sun-exposed epidermis of 23...

  • Quantitation of Cutaneous Langerhans Cells of Sarcoidosis Patients. Fox, Joshua L.; Berman, Brian; Teirstein, Alvin S.; France, Dennis S.; Reed, Michael L. // Journal of Investigative Dermatology;Jun83, Vol. 80 Issue 6, p472 

    Langerhans cells play a role in cell-mediated immune reactions which are often depressed in sarcoidosis. We examined the epidermis of 17 anergic patients with sarcoidosis (Kveim-reactive and/or biopsy-proved) for the number of Langerhans cells in noninvolved skin and in any cutaneous sarcoidal...

  • Langerhans Cell Histiocytosis of Maxilla and Mandible in 6 Years Old Child: A Case Report. Jindal, M. K.; Sharma, Vivek Kumar; Ahmed, Ibyne; Agrawal, Ashish // International Journal of Clinical Pediatric Dentistry;May-Aug2009, Vol. 2 Issue 2, p45 

    Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the proliferation of specialized bone marrow-derived Langerhans cells (LCs) and mature eosinophils. Its etiology is unknown but it could be due to antigenic stimulus of an infectious, genetic abnormality,...

  • ORIGINAL ARTICLE Thalidomide Inhibits Tumor Necrosis Factor-α Production and Antigen Presentation by Langerhans Cells. Liang Deng, Geoffrey; Wanhong Ding, Geoffrey; Granstein, Richard D. // Journal of Investigative Dermatology;Nov2003, Vol. 121 Issue 5, p1060 

    Thalidomide is an effective treatment for several inflammatory and autoimmune disorders including erythema nodosum leprosum, Behcet's syndrome, discoid lupus erythematosus, and Crohn's disease. Thalidomide is believed to exert its anti-inflammatory effects, at least in part, by inhibiting tumor...

  • Comparison of S-100 and OKT6 Antisera in Human Skin. Modlin, Robert L.; Rowden, Geoffrey; Taylor, Clive R.; Rea, Thomas H. // Journal of Investigative Dermatology;Sep84, Vol. 83 Issue 3, p206 

    The monoclonal antibody OKT6 and antisera against S-100 protein have both been advocated as immunologic markers of Langerhans cells in the skin. S-100 antiserum has an advantage in its ability to stain Langerhans cells in paraffin tissues. In order to evaluate whether these antibodies stain...

  • DERMATOLOGIC LOOK-ALIKES: Are you able to tell which is which?  // Cortlandt Forum;Jan2007, Vol. 20 Issue 1, p44 

    The article discusses two cases of skin diseases including palmoplantar keratoderma (PPK) and hand dermatitis (HD) or hand eczema. It presents the findings of the biopsy tests made to PPK and HD to differentiate one from the other. It also discusses the nature of each disease and their...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics