TITLE

Commentary: Gabapentin-Lactam and Gamma-Aminobutyric Acid/Lactam Analogs: The Enigma of Their Mechanism of Action

AUTHOR(S)
Feuerstein, Thomas J.
PUB. DATE
April 2011
SOURCE
Oral & Craniofacial Tissue Engineering;2011, Vol. 1 Issue 1, p29
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article offers information on gabapentin-lactam and gamma-aminobutyric acid/lactam analogs and the enigma of their mechanism of action. According to the author, the first publication on the possible mechanism of the action of gabapentin-lactam was released in 2000 which described the reduction by this drug of the oxygen glucose deprivation-induced neuronal glutamate release from rat hippocampal slices and its neuro-protective effect on ganglion cells in a model of acute retinal ischemia.
ACCESSION #
61029745

 

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