TITLE

Association between licence status and medication errors

AUTHOR(S)
Conroy, Sharon
PUB. DATE
March 2011
SOURCE
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Mar2011, Vol. 96 Issue 3, p305
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background and aims Unlicensed and off label drug use in children is common and leads to well-recognised problems. This study aimed to determine whether a relationship exists between medication errors and licence status. Methods Reports of errors in a UK children's hospital from 2004 to 2006 were analysed in terms of licence status and degree of harm and compared to the incidence of unlicensed and off label drug use in the hospital. Results 20 of 158 (13%) errors were considered to have caused moderate harm and 12 of these involved unlicensed/off label drugs. 138 (87%) caused no or low harm. None caused severe harm. Unlicensed drug usage was significantly more likely to be associated with errors than licensed use in both children and neonates. Conclusion Unlicensed drug use appears to be associated with medication errors in neonates and children. Medication errors causing moderate harm were significantly more likely to be associated with both unlicensed and off label than licensed drugs.
ACCESSION #
60944702

 

Related Articles

  • Off-label drug use among hospitalized children: identifying extent and nature. Slažneva, J.; Kovács, L.; Kuželová, M. // Acta Facultatis Pharmaceuticae Universitatis Comenianae;2012, Vol. 59 Issue 1, p48 

    Objective of the study was to determine the extent and nature of medicinal products used off-label in hospitalized children and to highlight the therapeutic areas with the highest need. Over a 4 week period, data about prescribed drugs to patients under 18 years of age at two paediatric wards in...

  • Používání léků mimo schválené indikace v pediatrii. Langerová, P.; Urbánek, K. // Czecho-Slovak Pediatrics / Cesko-Slovenska Pediatrie;Dec2011, Vol. 66 Issue 6, p380 

    No abstract available.

  • Off-label and unlicensed drug use high in Croatian children.  // PharmacoEconomics & Outcomes News;2/18/2012, Issue 647, p9 

    The article discusses research on the use of nonlicensed and off-label drugs in hospitalized children in Croatia, referencing a study by G. Palcevski and colleagues published in the "European Journal of Clinical Pharmacology."

  • AAP updates off-label drug use policy.  // Infectious Disease News;Apr2014, Vol. 27 Issue 4, p65 

    The article discusses a policy statement from the American Academy of Pediatrics, published online on February 24, 2014 by the journal "Pediatrics," regarding the prescribing of off-label drugs for children.

  • The Many Sides of Off-Label Prescribing. Epstein, R S; Huang, S-M // Clinical Pharmacology & Therapeutics;May2012, Vol. 91 Issue 5, p755 

    An introduction is presented in which the editor discusses various reports within the issue on topics including off-label prescribing of drugs, postmarketing surveillance and analysis tools for assessment of the adverse effects of labeled drugs and evaluation of drugs for pediatrics.

  • Prescription Errors in Psychiatry. Nair, Ashish; Srivastava, Mona // Internet Journal of Medical Update;Jul2013, Vol. 8 Issue 2, p70 

    Prescribing errors are common in mental health settings and a significant number of these errors may result in a serious outcome. In the majority of cases, simple steps such as reduced junior doctor workload, improved training in psychopharmacology and more direct supervision of prescribing may...

  • The impact of legislation on drug substances used off-label in paediatric wards-a nationwide study. Haslund-Krog, Sissel; Mathiasen, René; Christensen, Hanne; Holst, Helle // European Journal of Clinical Pharmacology;Apr2014, Vol. 70 Issue 4, p445 

    Purpose: This nationwide study is aimed at describing to what extent the European Paediatric Regulation has met therapeutic needs in children. Methods: Data for each drug substance in defined daily doses (DDD) were extracted from the national Danish data base. We evaluated if drug substances...

  • Off label use von Notfallmedikamenten im Kindesalter. Erker, C.G.; Möllmann, M. // Anaesthesist;Feb2013, Vol. 62 Issue 2, p130 

    In the medical treatment of children drugs are frequently used outside the boundaries of the approved licensing and use under the terms of off-label use is possible. However, this requires critical reasoning and experience with the drug involved. With help of a traffic light colored spreadsheet...

  • Better medicines for children: challenges and unmet needs. Slažneva, J.; Kákošová, V.; Kuželová, M. // Acta Facultatis Pharmaceuticae Universitatis Comenianae;2012 Supplement 6, Vol. 59, p21 

    This review deals with the use of medicinal products in children. Many medicinal products administered routinely to paediatric patients have been either not licensed for use in children (unlicensed use) or have been prescribed outside the terms of their product license (off-label prescribing). A...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics