Disclosure of Positive BRCA1/2-Mutation Status in Young Couples: The Journey From Uncertainty to Bonding Through Partner Support

September 2008
Families, Systems & Health: The Journal of Collaborative Family ;Sep2008, Vol. 26 Issue 3, p296
Academic Journal
BRCA1/2-positive women who learn their mutation status early in the life-course face unique challenges related to navigating the tasks of young adulthood. Using qualitative methods and grounded theory, the authors analyzed in-depth interviews with 11 women aged 26 to 35 who learned their mutation status before marriage. Their narratives illustrate the complexity of relationship formation, and highlight the potential for relationship-bonding and intimacy-building in the course of sharing mutation information. Disclosing BRCA mutation status to dating partners is often preceded by feelings of fear and anxiety, yet many participants reported that doing so has positive effects on relationships. Partners' abilities to respond with interest, empathy, and affection are associated with increased future intimacy, consistent with generally accepted principles within the family/couple systems field. Individual cancer risk perception and familial cancer experiences may affect the disclosure experience, which can be understood via Attachment Theory. Our findings provide clinical insight, identify new areas for research, and suggest ways to assist this unique population in their adjustment to being BRCA mutation-positive.


Related Articles

  • Women carrying BRCA mutations tied to breast and ovarian cancer may hit menopause a few years earlier than other women, according to a new study.  // MondayMorning;2/ 4/2013, Vol. 21 Issue 4, p1 

    The article focuses on a study which reveals that women suffering with BRCA mutation in BRCA1 and BRCA2 genes with breast and ovarian cancer have menopause earlier in comparison to other women. According to the U.S. National Cancer Institute, chance of breast cancer increases from 12 percent to...

  • Results of an Online Community Needs Assessment for Psychoeducational Interventions Among Partners of Hereditary Breast Cancer Previvors and Survivors. Tercyak, Kenneth P.; Mays, Darren; DeMarco, Tiffani A.; Sharff, McKane E.; Friedman, Susan // Journal of Medical Internet Research;Jan/Feb2012, Vol. 14 Issue 1, p24 

    Background: Spouses and partners ("partners") of women at-risk for ("previvors") and surviving with hereditary breast/ovarian cancer are a primary source of support within their families. Yet, little is known about partners' needs for psychoeducational intervention to enhance their cancer risk...

  • Assessing the Genetic Risk for BRCA-Related Breast or Ovarian Cancer in Women: Recommendations From the U.S. Preventive Services Task Force.  // Annals of Internal Medicine;2/18/2014, Vol. 160 Issue 4, pI-16 

    The article presents findings of a study titled "Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women: U.S. Preventive Services Task Force Recommendation Statement" by V. A. Moyer, that has been published within the issue. Topics discussed include analysis of...

  • Breast Cancer Risk After Salpingo-Oophorectomy in Healthy BRCA1/2 Mutation Carriers: Revisiting the Evidence for Risk Reduction. Heemskerk-Gerritsen, B. A. M.; Seynaeve, C.; van Asperen, C. J.; Ausems, M. G. E. M.; Collée, J. M.; van Doorn, H. C.; Gomez Garcia, E. B.; Kets, C. M.; van Leeuwen, F. E.; Meijers-Heijboer, H. E. J.; Mourits, M. J. E.; van Os, T. A. M.; Vasen, H. F. A.; Verhoef, S.; Rookus, M. A.; Hooning, M. J. // JNCI: Journal of the National Cancer Institute;5/13/2015, Vol. 107 Issue 5, p1 

    Background: Previous studies have reported a breast cancer (BC) risk reduction of approximately 50% after risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 mutation carriers, but may have been subject to several types of bias. The purpose of this nationwide cohort study was to assess...

  • Reevaluation of the BRCA2 truncating allele c.9976A >T (p.Lys3326Ter) in a familial breast cancer context. Thompson, Ella R.; Gorringe, Kylie L.; Rowley, Simone M.; Na Li; McInerny, Simone; Wong-Brown, Michelle W.; Devereux, Lisa; Li, Jason; Trainer, Alison H.; Mitchell, Gillian; Scott, Rodney J.; James, Paul A.; Campbell, Ian G. // Scientific Reports;10/9/2015, p1 

    The breast cancer predisposition gene, BRCA2, has a large number of genetic variants of unknown effect. The variant rs11571833, an A > T transversion in the final exon of the gene that leads to the creation of a stop codon 93 amino acids early (K3326*), is reported as a neutral polymorphism but...

  • Double heterozygosity in the BRCA1 and BRCA2 genes in the Jewish population. Lavie, O.; Narod, S.; Lejbkowicz, F.; Dishon, S.; Goldberg, Y.; Gemer, O.; Rennert, G. // Annals of Oncology;Apr2011, Vol. 22 Issue 4, p964 

    Background: The frequency and characteristics of disease in individuals who concomitantly harbor pathogenic mutations in both BRCA1 and BRCA2 genes are not established.Materials and methods: Data were collected from the database of Clalit Health Services National Familial Cancer Consultation...

  • Heeding genetic red flags for breast-cancer risk. Scott, Chey // Journal of Business (10756124);1/13/2011, Vol. 26 Issue 2, p11 

    The article focuses on the breast and ovarian cancer (BRCA) gene tests BRCA1 and BRCA2 offered at breast cancer health centers to its women patients which can tell the risk of developing cancer based on her heredity in Spokane, Washington. According to breast surgeon Deborah Martinez, some...

  • 17P THE BRCA CANCER GENE AS A USEFUL PREDICTOR FOR DOUBLE PRIMARY BREAST AND OVARIAN CANCER: A META-ANALYSIS. Sattaratnamai, A.; Eslick, G.D. // Annals of Oncology;May2014 Supplement 1, Vol. 25 Issue suppl_1, pi5 

    No abstract available.

  • Do I need a mastectomy? Phelps, Kerryn // Australian Women's Weekly;Aug2013, Vol. 83 Issue 8, p149 

    The article shares guide to women on how to determine who should consider mastectomy. It discusses the association between cancer risk and BReast CAncer (BRCA) susceptibility genes, the importance of seeking genetic counseling and testing, the scope of preventive mastectomy, and the risk of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics