Impact on antibiotic prescription of rapid antigen detection testing in acute pharyngitis in adults. a randomised clinical trial

Llor, Carl; Madurell, Jordi; Balagué-Corbella, Montse; Gómez, Mónica; Cots, Josep Maria
May 2011
British Journal of General Practice;May2011, Vol. 61 Issue 586, p335
Academic Journal
The article discusses a randomized clinical trial which examined the impact of rapid antigen detection testing (RADT) on antibiotic prescription in acute pharyngitis in adults. Findings revealed the greater likelihood of general practitioners (GP) without access to RADT to prescribe antibiotics compared with those who performed RADT. Based on the results, culture in 88 cases was found positive for group A beta haemolytic streptococcus (GABHS), while RADT was positive in 60 cases. Observation showed 226 cases of inappropriate antibiotic prescription.


Related Articles

  • Antibiotics for otitis media.  // Caribbean Health;Oct2000, Vol. 3 Issue 3, p29 

    The article focuses on a trial in the Netherlands which shows that even in young children, antibiotic treatment has little effect. The trial involved 240 children aging between 6 months and 2 years and attending 53 general practices for otitis media were randomised to oral amoxicillin 40...

  • Cluster randomized trials in general (family) practice research. Campbell, M.; Campbell, M J // Statistical Methods in Medical Research;Apr2000, Vol. 9 Issue 2, p81 

    Cluster randomized trials are increasingly common in general practice (family medicine). This paper will consider the design and analysis of such trials and emphasize the similarities and differences with trials in education, heath promotion and public health. Issues discussed are the estimation...

  • Roles of Clinician, Patient, and Community Characteristics in the Management of Pediatric Upper Respiratory Tract Infections. Yaeger, Jeffrey P.; Temte, Jonathan L.; Hanrahan, Lawrence P.; Martinez-Donate, Ana P.; Martinez-Donate, P // Annals of Family Medicine;Nov/Dec2015, Vol. 13 Issue 6, p529 

    Purpose: Prior studies have evaluated factors predictive of inappropriate antibiotic prescription for upper respiratory tract infections (URIs). Community factors, however, have not been examined. The aim of this study was to evaluate the roles of patient, clinician, and community...

  • Effect of two interventions on reducing antibiotic prescription in pharyngitis in primary care. Llor, Carl; Cots, Josep María; López-Valcárcel, Beatriz González; Alcántara, Juan de Dios; García, Guillermo; Arranz, Javier; Monedero, María José; Ortega, Jesús; Pineda, Vicenta; Guerra, Gloria; Gómez, Manuel; Hernández, Silvia; Paredes, José; Cid, Marina; Pérez, Carolina // Journal of Antimicrobial Chemotherapy (JAC);Jan2011, Vol. 66 Issue 1, p210 

    Objectives To evaluate the effect of two interventions on reducing antibiotic prescription in pharyngitis. Methods A prospective, non-randomized, before–after controlled study was carried out in primary care centres throughout Spain. General practitioners (GPs) registered all cases of...

  • Validnost primjene „Sore Throat Score” u praksi porodičnog ljekara. Milan, Mioković; Maja, Račić; Izet, Mašić // Materia Socio Medica;2008, Vol. 20 Issue 2, p101 

    Purpose: Decrease of antibiotic prescribing for the frequent respiratory infections which are characterized by sore throat is recommended as a way of prevention of antibiotic resistance. The study assesses the validity of existing score in the management of acute pharyngitis, in the family...

  • Representativeness of samples from general practice lists in epidemiological studies:case-control study. Smith, Alexandra G.; Fear, Nicola T.; Law, Graham R.; Roman, Eve // BMJ: British Medical Journal (International Edition);4/17/2004, Vol. 328 Issue 7445, p932 

    Presents a study of acute leukaemia in England and the issues that can compromise the validity and generalizability of a study. Description of the study and its results; Conclusion that sampling from a general practice register is a popular and convenient way of finding subjects, though...

  • Clinical trials in general practice. Greenberg, Gillian // BMJ: British Medical Journal (International Edition);10/19/91, Vol. 303 Issue 6808, p940 

    Focuses on the clinical trials in the general practice. Failures in the study of the role of treatment of the aged with isolate systolic hypertension in a general practice setting; Costs of conducting studies in general practice; Exploitation of the established research mechanism.

  • Randomised controlled trials in general practice. Pringle, Mike // BMJ: British Medical Journal (International Edition);11/25/95, Vol. 311 Issue 7017, p1382 

    Editorial. Focuses on problems related to the use of randomized trials as means of applying experimental methods in the general practice of medicine. Recruitment to randomized controlled trials; Problem concerning general practitioners' willingness to participate in experimental studies;...

  • Community-based recruitment of patients with COPD into clinical research. Brill, Simon E.; El-Emir, Ethaar; Allinson, James P.; Donaldson, Gavin C.; Nazareth, Irwin; Wedzicha, Jadwiga A. // Thorax;Oct2014, Vol. 69 Issue 10, p951 

    Identifying subjects for clinical trials is difficult and the evidence base for recruitment strategies is limited, particularly in the field of COPD. We compared the efficiency and patient characteristics of different community-based recruitment strategies during a non-commercial COPD trial in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics