Diagnostic value of symptoms for colorectal cancer in primary care: a systematic review

Hamilton, William; Astin, Margaret; Griffin, Tom; Neal, Richard D.; Rose, Peter
May 2011
British Journal of General Practice;May2011, Vol. 61 Issue 586, p333
Academic Journal
The article discusses a study which identified the risk of colorectal cancer in patients reporting a symptom to primary care. Based on the results of the study, the positive predictive values for rectal bleeding ranged from 2.2. percent to 15.8 percent. Symptoms with positive likelihood ratios were rectal bleeding, weight loss, abdominal pain, diarrhea and constipation. Analysis revealed paired symptoms with increased likelihood of colorectal cancer, including rectal bleeding with weight loss, and rectal bleeding with a change in bowel habit.


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