Blowing up reversibility in biomolecular self-assembly

Manno, Mauro; Emanuele, Antonio
April 2000
AIP Conference Proceedings;2000, Vol. 513 Issue 1, p158
Academic Journal
The self-assembly of hydrogels involves the interplay of many processes: thermodynamic demixing, molecular crosslinking and molecular conformational changes. Interactions among these processes lead to complex structures encompassing many length-scales. Here, we monitor experimentally changes of the structure of biomolecular aggregates during the melting of an agarose gel, that is during the inverse process of gelation, which exhibits a large hysteresis. Observations on different lengthscales clarify the role of the processes involved in sustaining irreversibility. © 2000 American Institute of Physics.


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