Epitope-grafted and Antigenized Antibodies Can Be Used For Versatile Vaccination Strategies to Induce Epitope-specific Immune Responses

Kumagai, Yoshihiro
April 2011
Journal of Nippon Medical School;2011, Vol. 78 Issue 2, p66
Academic Journal
The article focuses on the use of epitope-grafted and antigenized antibodies as idiotypic vaccines to induce Epitope-specific Immune Responses. It states that the V3 sequences of human immunodeficiency virus (HIV) are highly neutralizing the determinants of HIV-1 infection in vitro and the sites to determine tropism. A diagram showing the bind to Fc receptors on antigen-presenting cells and a chart showing the localization of antigenized antibodies are presented.


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