TITLE

Current Concepts in Antimicrobial Therapy Against Resistant Gram-Negative Organisms: Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae, Carbapenem-Resistant Enterobacteriaceae, and Multidrug-Resistant Pseudomonas aeruginosa

AUTHOR(S)
KANJ, SOUHA S.; KANAFANI, ZEINA A.
PUB. DATE
March 2011
SOURCE
Mayo Clinic Proceedings;Mar2011, Vol. 86 Issue 3, p250
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The development of antimicrobial resistance among gram-negative pathogens has been progressive and relentless. Pathogens of particular concern include extended-spectrum β-lactamase-producing Enterobacterlaceae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa. Classic agents used to treat these pathogens have become out-dated. Of the few new drugs available, many have already become targets for bacterial mechanisms of resistance. This review describes the current approach to infections due to these resistant organisms and elaborates on the available treatment options. Mayo Clin Proc. 2011;86(3):250-259
ACCESSION #
60010655

 

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